Staff Profile

Dr Alison Yarnall completed her PhD in 2013 at Newcastle University looking at biomarkers of cognitive impairment in Parkinson’s disease. She is now an NIHR BRC Clinical Senior Lecturer at the Translational and Clinical Research Institute, Newcastle University; Deputy Director of the Clinical Ageing Research Unit; and Honorary Consultant in Older People’s Medicine at Newcastle upon Tyne Hospitals (NuTH) NHS Foundation Trust. She has a particular interest in cognitive decline, gait and falls in people with Parkinson’s and other neurodegenerative diseases and has published more than 100 articles in this topic area.  She runs a specialist clinic for older adults with Parkinson’s and complex health needs in NuTH, in addition to a general medical memory clinic.

Areas of expertise

• Parkinson's disease
• Biomarkers
• Gait and mobility
• Dementia
• Ageing syndromes

SCOPUS: Click here.

• Minett T, Su L, Mak E, Williams G, Firbank M, Lawson RA, Yarnall AJ, Duncan GW, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn D, O'Brien JT. Longitudinal diffusion tensor imaging changes in early Parkinson’s disease: ICICLE-PD study. Journal of Neurology 2018, 265(7), 1528-1539.
• Ross A, Yarnall AJ, Rochester L, Lord S. A novel approach to falls classification in Parkinson’s disease: Development of the Fall-Related Activity Classification (FRAC). Physiotherapy 2017, 103(4), 459-464.
• Dissanayaka NNW, Lawson RA, Yarnall AJ, Duncan GW, Breen DP, Khoo TK, Barker RA, Burn DJ. Anxiety is associated with cognitive impairment in newly-diagnosed Parkinson’s disease. Parkinsonism & Related Disorders 2017, 36, 63–68.
• Firbank MJ, Yarnall AJ, Lawson RA, Duncan GW, Khoo TK, Petrides GS, O'Brien JT, Barker RA, Maxwell RJ, Brooks DJ, Burn DJ. Cerebral glucose metabolism and cognition in newly diagnosed Parkinson’s disease: ICICLE-PD study. Journal of Neurology, Neurosurgery, and Psychiatry 2017, 88(4), 310-316.
• Lawson RA, Yarnall AJ, Johnston F, Duncan GW, Khoo TK, Collerton D, Taylor JP, Burn DJ, on behalf of the ICICLE-PD study group. Cognitive impairment in Parkinson's disease: impact on quality of life carers. International Journal of Geriatric Psychiatry 2017, 32(12), 1362-1370.
• Rochester L, Galna B, Lord S, Yarnall AJ, Morris R, Duncan G, Khoo TK, Mollenhauer B, Burn DJ. Decrease in Aβ42 predicts dopa-resistant gait progression in early Parkinson’s disease. Neurology 2017, 88(16), 1501-1511.
• Morris R, Lord S, Lawson RA, Coleman S, Galna B, Duncan GW, Khoo TK, Yarnall AJ, Burn DJ, Rochester L. Gait Rather Than Cognition Predicts Decline in Specific Cognitive Domains in Early Parkinson’s Disease. Journal of Gerontology: Series A 2017, 72(12), 1656-1662.
• Lord S, Galna B, Yarnall AJ, Coleman S, Burn D, Rochester L. Have we been overestimating fall rates in Parkinson's disease?. Movement Disorders 2017, 32(5), 803-804.
• Peraza LR, Nesbitt D, Lawson RA, Duncan GW, Yarnall AJ, Khoo TK, Kaiser M, Firbank MJ, O'Brien JT, Barker RA, Brooks DJ, Burn DJ, Taylor JP. Intra- and inter-network functional alterations in Parkinson's disease with mild cognitive impairment. Human Brain Mapping 2017, 38(3), 1702-1715.
• Mak E, Su L, Williams GB, Firbank MJ, Lawson RA, Yarnall AJ, Duncan GW, Mollenhauer B, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn DJ, O'Brien JT. Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease. Neurobiology of Aging 2017, 55, 78-90.
• Burte F, Houghton D, Lowes H, Pyle A, Nesbitt S, Yarnall A, Yu-Wai-Man P, Burn DJ, Santibanez-Koref M, Hudson G. Metabolic profiling of Parkinson's disease and mild cognitive impairment. Movement Disorders 2017, 32(6), 927–932.
• Lord S, Galna B, Yarnall AJ, Morris R, Coleman S, Burn D, Rochester L. Natural history of falls in an incident cohort of Parkinson’s disease: early evolution, risk and protective features. Journal of Neurology 2017, 264(11), 2268-2276.
• Yarnall AJ, Sayer AA, Clegg A, Rockwood K, Parker S, Hindle JV. New Horizons in Multimorbidity in Older Adults. Age and Ageing 2017, 46(6), 882-888.
• O'Dowd S, Galna B, Morris R, Lawson RA, McDonald C, Yarnall AJ, Burn DJ, Rochester L, Anderson KN. Poor Sleep Quality and Progression of Gait Impairment in an Incident Parkinson’s Disease Cohort. Journal of Parkinson's Disease 2017, 7(3), 465-470.
• Stuart S, Alcock L, Nell J, Lawson RA, Morris R, Yarnall AJ, Burn D, Rochester L. Pro-saccades predict decline in attention over 18 months in newly diagnosed Parkinson’s disease. In: 21st International Congress of Parkinson's Disease and Movement Disorders. 2017, Vancouver, BC, Canada: John Wiley & Sons, Inc.
• Lawson RA, Yarnall AJ, Duncan GW, Breen DP, Khoo TK, Williams-Gray CH, Barker RA, Burn DJ. Stability of mild cognitive impairment in newly diagnosed Parkinson’s disease. Journal of Neurology, Neurosurgery & Psychiatry 2017, 88, 648-652.
• Sleeman I, Aspray T, Lawson RA, Coleman S, Duncan GW, Khoo TK, Schoenmakers I, Barker R, Rochester R, Burn DJ, Yarnall AJ. The Role of Vitamin D in Disease Progression in Early Parkinson’s Disease. Journal of Parkinson's Disease 2017, 7(4), 669-675.
• Yarnall AJ, Lashley T, Ling H, Lees AJ, Coleman SY, O'Sullivan SS, Compta Y, Revesz T, Burn DJ. Apomorphine: A potential modifier of amyloid deposition in Parkinson's disease?. Movement Disorders 2016, 31(5), 668-675.
• Lawson RA, Yarnall AJ, Duncan GW, Khoo TK, Breen DP, Williams-Gray CH, Barker RA, Collerton D, Taylor JP, Burn DJ. Cognitive decline and quality of life in incident Parkinson’s disease: the role of attention. Parkinsonism and Related Disorders 2016, 27, 47-53.
• Duncan GW, Firbank MJ, Yarnall AJ, Khoo TK, Brooks DJ, Barker RA, Burn DJ, O'Brien JT. Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease?. Movement Disorders 2016, 31(1), 103-110.
• Lord S, Galna B, Yarnall AY, Coleman S, Burn D, Rochester L. Predicting first fall in newly diagnosed Parkinson's disease: Insights from a fall-naïve cohort. Movement Disorders 2016, 31(12), 1829-1836.
• Peraza LR, Lawson RA, Firbank JM, Yarnall A, Duncan GW, Khoo TK, Brooks D, O'Brien JT, Barker RA, Burn D, Taylor JP. Principal component discriminant analysis of mild cognitive impairment in Parkinson’s disease reveals early functional changes in the resting state. In: Neuroinformatics 2016 INCF Conference. 2016, Reading, UK: Frontiers Media S.A.
• Pyle A, Anugrha H, Kurzawa-Akanbi M, Yarnall A, Burn D, Hudson G. Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease. Neurobiology of Aging 2016, 38, 216.e7–216.e10.
• Pyle A, Lowes H, Brennan R, Kurzawa-Akanbi M, Yarnall A, Burn D, Hudson G. Reduced Mitochondrial DNA Is Not a Biomarker of Depression in Parkinson's Disease. Movement Disorders 2016, 31(12), 1923-1924.
• Williams-Gray CH, Wijeyekoon R, Yarnall AJ, Lawson RA, Breen DP, Evans JR, Cummings GA, Duncan GW, Khoo TK, Burn DJ, Barker RA, on behalf of the ICICLE-PD study group. Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD). Movement Disorders 2016, 31(7), 995-1003.
• Yarnall AJ, Ho BSW, Eshun E, David R, Rochester L, Burn DJ, Baker MR. Short latency afferent inhibition: Effects of ageing. Clinical Neurophysiology 2016, 127(6), 2410-2413.
• McDonald C, Lawson RA, Duncan GW, O'Dowd ST, Khoo TK, Yarnall AJ, Burn DJ. The Frequency and Progression of Genitourinary and Gastrointestinal Symptoms in Parkinson’s disease and Healthy Controls Over 36 months Follow-up in the ICICLE-PD Study. In: Parkinson’s UK Research Conference. 2016, Leeds.
• Yarnall AJ, Lawson RA, Duncan GW, Breen DP, Khoo TK, Brooks D, Barker RA, Taylor JP, Burn DJ. Anticholinergic Load: Is there a Cognitive Cost in Early Parkinson's Disease?. Journal of Parkinson's Disease 2015, 5(4), 743-743.
• Mak E, Su L, Williams GB, Firbank MJ, Lawson RA, Yarnall AJ, Duncan GW, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn DJ, O'Brien JT. Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain 2015, 138, 2974-2986.
• Mak E, Su L, Williams G, Lawson R, Yarnall A, Gordon D, Adrian O, Tien K, Brooks D, Rowe J, Barker R, Burn D, O'Brien J. Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study. In: 17th IPA International. 2015, Berlin, Germany: Cambridge University Press.
• Critchley RJ, Khan SK, Yarnall AJ, Parker MJ, Deehan DJ. Occurrence, management and outcomes of hip fractures in patients with Parkinson's disease. British Medical Bulletin 2015, 115(1), 135-142.
• Pyle A, Brennan R, Kurzawa-Akanbi M, Yarnall A, Thouin A, Mollenhauer B, Burn D, Chinnery PF, Hudson G. Reduced CSF mitochondrial DNA is a biomarker for early-stage Parkinson's disease. Annals of Neurology 2015, 78(6), 1000-1004.
• Vardy ERLC, Teodorczuk A, Yarnall AJ. Review of delirium in patients with Parkinson's disease. Journal of Neurology 2015, 262(11), 2401-2410.
• Carbutt S, Duff J, Yarnall A, Burn DJ, Hudson G. Variation in complement protein C1q is not a major contributor to cognitive impairment in Parkinson's disease. Neuroscience Letters 2015, 594, 66-69.
• Yarnall AJ, Breen DP, Duncan GW, Khoo TK, Coleman SY, Firbank MJ, Nombela C, Winder-Rhodes S, Evans JR, Rowe JB, Mollenhauer B, Kruse N, Hudson G, Chinnery PF, O'Brien JT, Robbins TW, Wesnes K, Brooks DJ, Barker RA, Burn DJ, ICICLE-PD Study Group. Characterizing mild cognitive impairment in incident Parkinson disease The ICICLE-PD Study. Neurology 2014, 82(4), 308-316.
• Lord S, Galna B, Coleman S, Yarnall A, Burn D, Rochester L. Cognition and gait show a selective pattern of association dominated by phenotype in incident Parkinson's disease. Frontiers in Aging Neuroscience 2014, 6, 249.
• Rochester L, Lord S, Yarnall AJ, Burn DJ. Falls in patients with dementia. In: Movement Disorders in Dementias. London: Springer, 2014, pp.45-60.
• Nesbitt D, Peraza LR, Lawson R, Yarnall A, Firbank M, Taylor J-P, Burn D. fMRI resting state connectivity in Parkinson's with mild cognitive impairment. In: Parkinson's UK Research Conference. 2014, York, UK.
• Nombela C, Rowe JB, Winder-Rhodes SE, Hampshire A, Owen AM, Breen DP, Duncan GW, Khoo TK, Yarnall AJ, Firbank MJ, Chinnery PF, Robbins TW, O'Brien JT, Brooks DJ, Burn DJ, Barker RA, ICICLE-PD Study Grp. Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain 2014, 137, 2743-2758.
• Duncan GW, Khoo TK, Yarnall AJ, O'Brien JT, Coleman SY, Brooks DJ, Barker RA, Burn DJ. Health-related quality of life in early Parkinson's disease: The impact of nonmotor symptoms. Movement Disorders 2014, 29(2), 195-202.
• Burn DJ, Yarnall AJ. Motor symptoms and phenotype in patients with Parkinson’s disease dementia. In: Murat Emre, ed. Cognitive Impairment and Dementia in Parkinson's Disease. 2014.
• Yarnall AJ, Del Din S, David R, Galna B, Baker MR, Burn DJ, Rochester L. Postural control stabilises over the first 30 seconds of quiet standing in Parkinson’s disease: time series analysis. In: International Parkinson and Movement Disorder Society's 18th International Congress of Parkinson's Disease and Movement Disorders. 2014, Stockholm, Sweden.
• Prudon B, Duncan GW, Khoo TK, Yarnall AJ, Burn DJ, Anderson KN. Primary sleep disorder prevalence in patients with newly diagnosed Parkinson's Disease. Movement Disorders 2014, 29(2), 259-262.
• Lawson RA, Yarnall AJ, Duncan GW, Khoo TK, Breen DP, Barker RA, Collerton D, Taylor JP, Burn DJ. Quality of Life and Mild Cognitive Impairment in Early Parkinson's Disease: Does Subtype Matter?. Journal of Parkinson's Disease 2014, 4(3), 331-336.
• Lawson RA, Yarnall AJ, Duncan GW, Khoo TK, Breen DP, Barker RA, Collerton D, Taylor JP, Burn DJ. Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life. Parkinsonism & Related Disorders 2014, 20(10), 1071-1075.
• Duncan GW, Khoo TK, Coleman SY, Brayne CE, Yarnall AJ, O'Brien JT, Barker RA, Burn DJ. The Incidence of Parkinson's Disease in the North East of England. Age and Ageing 2014, 43(2), 257-263.
• Yarnall AJ. What are the priorities in Parkinson’s disease clinical research? A focus on motor complications, gait and cognition. Neurodegenerative Disease Management 2014, 4(2), 127-136.
• Dobson R, Yarnall AJ, Noyce A, Giovannoni G. Bone health in chronic neurological diseases: a focus on multiple sclerosis and parkinsonian syndromes. Practical Neurology 2013, 13(2), 70-79.
• Burn DJ, Yarnall AJ. Dementia in Parkinson’s Disease. In: Chaudhuti, K.R., Tolosa, E., Schapira, A., Poewe, W, ed. Non-Motor Symptoms of Parkinson's Disease. Oxford, UK: Oxford University Press, 2013.
• Duncan GW, Yarnall AJ, Firbank MJ, Barker RA, O'Brien JT, Burn DJ. Grey matter and CSF amyloid in early non-demented Parkinson's disease: the incidence of cognitive impairment in cohorts with longitudinal evaluation - Parkinson's disease (ICICLE-PD) study. In: Association of British Neurologists Annual Meeting 2013. 2013, Glasgow, UK: Association of British Neurologists.
• Duncan GW, Firbank MJ, Yarnall AJ, Barker RA, O'Brien JT, Burn DJ. Grey matter correlations of cognitive impairment in early Parkinson's disease: the incidence of cognitive impairment in cohorts with longitudinal evaluation - Parkinson's disease (ICICLE-PD) study. In: British Geriatrics Society Spring Meeting. 2013, Belfast: British Geriatrics Society.
• Duncan GW, Firbank MJ, Yarnall AJ, Barker RA, Burn DJ. Grey matter correlations of cognitive impairment in early Parkinson's disease: the incidence of cognitive impairment in cohorts with longitudinal evaluation - Parkinson's disease (ICICLE-PD) study. In: Association of British Neurologists Annual Meeting 2013. 2013, Glasgow: Association of British Neurologists.
• Duncan GW, Firbank MJ, Yarnall AJ, Khoo TK, O'Brien JT, Barker RA, Burn DJ. Grey Matter Correlations of Cognitive Impairment in Early Parkinson's Disease: The Incidence of Cognitive Impairment In Cohorts with Longitudinal Evaluation: Parkinson's Disease (ICICLE-PD) Study. In: Age and Ageing. 2013, Oxford: Oxford University Press.
• Duncan GW, Firbank MJ, Yarnall AJ, Barker RA, O'Brien JT, Burn DJ. Grey Matter Correlations of Cognitive Impairment in Early Parkinson's Disease: The Incidence of Cognitive Impairment in Cohorts with Longitudinal Evaluation-Parkinson's Disease (ICICLE-PD) Study. In: Association of British Neurologists (ABN) Joint Meeting with the Royal College of Physicians (RCP). 2013, London, UK: BMJ Group.
• Yarnall AJ, Rochester L, Burn DJ. Mild cognitive impairment in Parkinson's disease. Age and Ageing 2013, 42(5), 567-576.
• Duncan GW, Yarnall AJ, Marrinan S, Burn DJ. New horizons in the pathogenesis, assessment and management of movement disorders. Age and Ageing 2013, 42(1), 2-10.
• Prudon B, Duncan GW, Yarnall AJ, Burn DJ, Anderson K. Primary sleep disorder prevalence in patients with newly diagnosed Parkinson's disease. In: American Thoracic Society International Conference. 2013, Philadelphia: American Thoracic Society.
• Ford AH, Duncan GW, Firbank MJ, Yarnall AJ, Khoo TK, Burn DJ, O'Brien JT. Rapid eye movement sleep behavior disorder in Parkinson's disease: Magnetic resonance imaging study. Movement Disorders 2013, 28(6), 832-836.
• Yarnall AJ, Rochester L, Baker MR, David R, Khoo TK, Duncan GW, Galna B, Burn DJ. Short latency afferent inhibition: A biomarker for mild cognitive impairment in Parkinson's disease?. Movement Disorders 2013, 28(9), 1285-1288.
• Boucher JJ, Duncan GW, Yarnall AJ, Martin Ruiz C, Barker RA, O'Brien JT, Von Zglinicki T, Burn DJ. Telomere length and cognitive impairment in early Parkinson's disease. In: 49th Annual Meeting of the Irish Neurological Association. 2013, Dublin: Irish Neurological Association.
• Duncan GW, Khoo TK, Yarnall AJ, O'Brien JT, Barker RA, Burn DJ. The impact of motor and non-motor symptoms upon health-related quality of life in early Parkinson's disease: the incidence of cognitive impairment in cohorts with longitudinal evaluation: Parkinson's Disease (ICICLE-PD) Study. In: British Geriatrics Society Spring Meeting. 2013, Belfast, Ireland: Oxford University Press.
• Khoo TK, Yarnall AJ, Duncan GW, Coleman S, O'Brien JT, Brooks DJ, Barker RA, Burn DJ. The spectrum of nonmotor symptoms in early Parkinson disease. Neurology 2013, 80(3), 276-281.
• Schoenmakers I, Francis RM, McColl E, Chadwick T, Goldberg GR, Harle C, Yarnall A, Wilkinson J, Parker J, Prentice A, Aspray T. Vitamin D supplementation in older people (VDOP): Study protocol for a randomised controlled intervention trial with monthly oral dosing with 12,000 IU, 24,000 IU or 48,000 IU of vitamin D₃. Trials 2013, 14, 299.
• Yarnall AJ, Burn DJ. Amantadine-induced myoclonus in a patient with progressive supranuclear palsy. Age and Ageing 2012, 41(5), 695-696.
• Yarnall AJ, Khoo TK, Duncan GW, Barker RA, Brooks DJ, Burn DJ. Anti-cholinergic load: Is there a cognitive cost in early Parkinson’s disease?. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Khoo TK, Duncan GW, Yarnall AJ, Brooks DJ, Barker RA, O'Brien JT, Burn DJ. Apathy in incident Parkinson’s disease. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Rochester L, Yarnall A, Baker MR, David R, Lord S, Galna B, Burn DJ. Cholinergic dysfunction contributes to gait disturbance in early Parkinson’s disease. Brain 2012, 135(9), 2778-2787.
• Yarnall AJ, Rochester L, David R, Duncan GW, Khoo TK, Barker RA, Brooks DJ, Baker MR, Burn DJ. Cholinergic dysfunction in Parkinson’s disease with mild cognitive impairment: a short latency afferent inhibition study. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Khoo TK, Duncan GW, Yarnall AJ, Brooks DJ, Barker RA, O'Brien JT, Burn DJ. Depression and anxiety in incident Parkinson’s disease. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Yarnall AJ, Hayes L, Hawthorne GC, Candlish CA, Aspray TJ. Diabetes in care homes: current care standards and residents' experience. Diabetic Medicine 2012, 29(1), 132-135.
• Duncan GW, Khoo TK, Yarnall AJ, O'Brien JT, Brooks DJ, Barker RA, Burn DJ. Elevated homocysteine levels and cognitive dysfunction in an incident cohort of non-demented Parkinson’s disease patients. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Yarnall AJ, Duncan GW, Khoo TK, Burn DJ. Falling short: Underestimation of fracture risk in atypical parkinsonian syndromes. Parkinsonism and Related Disorders 2012, 18(5), 692-693.
• Nombela C, Rowe J, Hampshire A, Owen A, Breen D, Winder-Rhodes S, Khoo T, Firbank M, Yarnall A, Duncan G, O'Brien J, Burn D, Brooks D, Barker R. Inefficiency of fronto-parietal networks in incident Parkinson’s disease. In: 8th Forum of Neuroscience. 2012, Barcelona, Spain.
• Yarnall AJ, Archibald N, Burn DJ. Parkinson’s disease. Medicine 2012, 40 (10).
• Nombela C, Rowe J, Hampshire A, Owen A, Breen D, Khoo T, Firbank M, Yarnall A, Duncan G, O'Brien J, Burn D, Brooks D, Barker R. Spatial planning ability in early stage Parkinson’s disease patients (ICICLE-PD). In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Khoo TK, Duncan GW, Yarnall AJ, Brooks DJ, Barker RA, O'Brien JT, Burn DJ. The incidence of Parkinson’s disease in North East England. In: The Movement Disorders Society 16th International Congress of Parkinson’s Disease and Movement Disorders. 2012, Dublin, Ireland.
• Hawthorne GC, Yarnall AJ. Cardiovascular risk, Glucose and Targets for Management of Diabetes in Older People. In: Springer, ed. Diabetes for the Older Person: A Practical Handbook. 2011.
• Yarnall AJ, Hayes L, Hawthorne GC, Candlish C, Aspray TJ. Diabetes in care homes: Residents' experience of care. In: Age and Ageing: Communications to the British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
• Yarnall AJ. Low CSF alpha-Synuclein Levels May Facilitate the Prediction of Synucleinopathies. Movement Disorders 2011, 26(7), 1194-1194.
• Yarnall A, Rochester L, Burn DJ. The interplay of cholinergic function, attention, and falls in Parkinson's disease. Movement Disorders 2011, 26(14), 2496-2503.
• Yarnall AJ, Hawthorne GC. Recent clinical trials in diabetes- implications for managing older patients. Reviews in Clinical Gerontology 2009, 19(1), 25-33.
• Furness JC, Hampton F, Barwick C, Howarth D, Innes L, Yarnall A, Harvey H, Spencer DA. Tolerance of spacers with masks is frequently poor in young children. In: Thorax. 2001, BMJ Group.
• Naisby J, Amjad A, Ratcliffe N, Yarnall AJ, Rochester L, Walker R, Baker K. A Survey of People With Parkinson’s and Their Carers: The Management of Pain in Parkinson’s . Journal of Geriatric Psychiatry and Neurology 2021, 35(4), 613-621.
• Del Din S, Kirk C, Yarnall AJ, Rochester L, Hausdorff JM. Body-Worn Sensors for Remote Monitoring of Parkinson’s Disease Motor Symptoms: Vision, State of the Art, and Challenges Ahead. Journal of Parkinson's Disease 2021, 11(S1), S35-S47.
• Wilson J, Yarnall AJ, Craig CE, Galna B, Lord S, Morris R, Lawson RA, Alcock L, Duncan GW, Khoo TK, O'Brien JT, Burn DJ, Taylor JP, Ray NJ, Rochester L. Cholinergic Basal Forebrain Volumes Predict Gait Decline in Parkinson's Disease. Movement Disorders 2021, 36(3), 611-621.
• Lawson RA, Richardson SJ, Kershaw D, Davis D, Stephan B, Robinson L, Brayn C, Barnes L, Yarnall AJ, Taylor JP, Burn DJ, Parker S, Allan LM. Evaluation of bedside tests of attention and arousal assessing delirium in Parkinson’s disease, dementia and older adults. Journal of Parkinson's Disease 2021, (ePub ahead of Print).
• Vijiaratnam N, Girges C, Auld G, Chau M, MacLagan K, King A, Skene SS, Chowdhury K, Hibbert S, Morris H, Limousin P, Athauda D, Carroll C, Hu MT, Silverdale M, Duncan GW, Chaudhuri R, Lo C, Del Din S, Yarnall AJ, Rochester L, Gibson R, Dickson J, Hunter R, Libri V, Foltynie T. Exenatide once weekly over 2 years as a potential disease modifying treatment for Parkinson's disease: protocol for a multi-centre, randomised, double blind, parallel group, placebo controlled, Phase 3 trial, The 'Exenatide-PD3' study. BMJ Open 2021, 11(5), e047993.
• Mc Ardle R, Del Din S, Yarnall A. Gait analysis as a clinical tool for dementia: current perspectives and future challenges. Advances in Clinical Neuroscience and Rehabilitation (ACNR) 2021. In Press.
• Sigurdsson HP, Raw R, Hunter H, Baker MR, Taylor J-P, Rochester L, Yarnall AJ. Noninvasive vagus nerve stimulation in Parkinson’s disease: current status and future prospects. Expert Review of Medical Devices 2021, Epub ahead of print.
• Rehman RZU, Rochester L, Yarnall AJ, Del Din S. Predicting the Progression of Parkinson’s Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning. In: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). 2021, Mexico: IEEE.
• Waite SJ, Maitland S, Thomas A, Yarnall AJ. Sarcopenia and frailty in individuals with dementia: A systematic review. Archives of Gerontology and Geriatrics 2021, 92, 104268.
• Colloby SJ, Nathan P, Bakker G, Lawson RA, Yarnall AJ, Burn DJ, OBrien JT, Taylor JP. Spatial covariance of cholinergic muscarinic M₁/M₄ receptors in Parkinson’s disease. Movement Disorders 2021, 36(8), 1879-1888.
• Mazzà C, Alcock L, Aminian K, Becker C, Bertuletti S, Bonci T, Brown P, Brozgol M, Buckley E, Carsin A, Caruso M, Caulfield B, Cereatti A, Chiari L, Chynkiamis N, Ciravegna F, Del Din S, Eskofier B, Evers J, Garcia-Aymerich J, Gazit E, Hansen C, Hausdorff J, Helbostad J, Hiden H, Hume E, Paraschiv-Ionescu A, Ireson N, Keogh A, Kirk C, Kluge F, Koch S, Küderle A, Lanfranchi V, Maetzler W, Micó-Amigo EM, Mueller A, Neatrour I, Niessen M, P Luca, P L, Reggi L, Salis F, Schwickert L, Scott K, Sharrack B, Sillen H, Singleton D, Soltani A, Taraldsen K, Ullrich M, Van Gelder L, Vereijken B, Vogiatzis I, Warmerdam E, Yarnall A, Rochester L. Technical validation of real-world monitoring of gait: a multicentric observational study. BMJ Open 2021, 11(12), e050785.
• Naisby J, Lawson RA, Galna B, Alcock L, Burn DJ, Rochester L, Yarnall AJ. Trajectories of pain over six years in early Parkinson’s disease: ICICLE-PD. Journal of Neurology 2021, 268, 4759-4767.
• Polhemus A, Delgado Ortiz L, Brittain G, Chynkiamis N, Salis F, Habner H, Gross M, Kirk C, Rossanigo R, Taraldsen K, Balta D, Bruels S, Buttery S, Cardenas G, Endress C, Gugenham J, Keogh A, Kluge F, Kock S, Mico-Amigo E, Nerz C, Sieber C, Williams P, Bergquist R, Bosch de Basea M, Buckley E, Hansen C, Mikolaizak A, Schwickert L, Scott K, Stallforth S, van Uem J, Vereijken B, Cereatti A, Demeyer H, Hopkinsons N, Maeltzler W, Troosters T, Vogiatzis I, Yarnall A, Becker C, Garcia-Aymerich J, Leocani L, Mazza C, Rochester L, Sharrack B, Frei A, Puhan M. Walking on common ground: A cross-disciplinary scoping review on the clinical utility of digital mobility outcomes. npj digital medicine 2021, 4, 149.
• Lawson RA, Williams-Gray CH, Camacho M, Duncan GW, Khoo TK, Breen DP, Barker RA, Rochester L, Burn DJ, Yarnall AJ. Which neuropsychological tests? Predicting cognitive decline and dementia in Parkinson’s disease in the ICICLE-PD cohort. Journal of Parkinson's Disease 2021, 11(3), 1297-1308.
• Del Din S, Yarnall AJ, Barber TR, Lo C, Crabbe M, Rolinski M, Baig F, Hu MT, Rochester L. Continuous Real-World Gait Monitoring in Idiopathic REM Sleep Behavior Disorder. Journal of Parkinson's Disease 2020, 10(1), 283-299.
• Wilson J, Alcock L, Yarnall AJ, Lord S, Lawson RA, Morris R, Taylor J-P, Burn DJ, Rochester L, Galna B. Gait Progression Over 6 Years in Parkinson’s Disease: Effects of Age, Medication, and Pathology. Frontiers in Aging Neuroscience 2020, 12, 577435.
• Lawson RA, Richardson SJ, Yarnall AJ, Burn DJ, Allan LM. Identifying delirium in Parkinson’s disease: a pilot study. International Journal of Geriatric Psychiatry 2020, 35(5), 547-552.
• Durcan R, Donaghy PC, Barnett NA, Olsen K, Yarnall AJ, Taylor J-P, McKeith I, O'Brien JT, Thomas AJ. Prevalence and severity of symptoms suggestive of gastroparesis in prodromal dementia with Lewy bodies. International Journal of Geriatric Psychiatry 2020, 34(7), 990-998.
• Dlay JK, Duncan GW, Khoo TK, Williams-Gray CH, Breen DP, Barker RA, Burn DJ, Lawson RA, Yarnall AJ. Progression of Neuropsychiatric Symptoms over Time in an Incident Parkinson’s Disease Cohort (ICICLE-PD). Brain Sciences 2020, 10(2), 78.
• Martin-Ruiz C, Williams-Gray CH, Yarnall AJ, Boucher JJ, Lawson RA, Wijeyekoon RS, Barker RA, Kolenda C, Parker C, Burn DJ, Von Zglinicki T, Saretzki G. Senescence and inflammatory markers for predicting clinical progression in Parkinson's disease-the ICICLE-PD study. Journal of Parkinson's Disease 2020, 10(1), 193-206.
• Yarnall AJ, Granic A, Waite S, Hollingsworth KG, Warren C, Vincent AE, Turnbull DM, Taylor RW, Dodds RM, Sayer AA. The feasibility of muscle mitochondrial respiratory chain phenotyping across the cognitive spectrum in Parkinson’s disease. Experimental Gerontology 2020, 138, 110997.
• Lowes H, Robertson F, Pyle A, Hussain R, Coxhead J, Yarnall AJ, Burn D, Payne BAI, Santibanez-Koref M, Hudson G. The Human Coronavirus Receptor ANPEP (CD13) Is Overexpressed in Parkinson's Disease. Movement Disorders 2020, 35(12), 2134-2136.
• Law ZK, Todd C, Mehraram R, Schumacher J, Baker MR, LeBeau FEN, Yarnall A, Onofrj M, Bonanni L, Thomas A, Taylor J-P. The role of EEG in the diagnosis, prognosis and clinical correlations of Dementia with Lewy Bodies—a systematic review. Diagnostics 2020, 10(9), 616.
• Ramsay N, Macleod AD, Alves G, Camacho M, Forsgren L, Lawson RA, Maple-Grødem J, Tysnes OB, Williams-Gray CH, Yarnall AJ, Counsell CE. Validation of a UPDRS-/MDS-UPDRS-based definition of functional dependency for Parkinson’s disease. Parkinsonism and Related Disorders 2020, 76, 49-53.
• Polhemus AM, Bergquist R, Bosch de Basea M, Brittain G, Buttery S, Chynkiamis N, dalla Costa G, Delgado Ortiz L, Demeyer H, Emmert K, Garcia-Aymerich J, Gassner H, Hansen C, Hopkinson NS, Klucken J, Kluge F, Koch S, Leocani L, Maetzler W, Micó-Amigo ME, Mikolaizak AS, Piraino P, Salis F, Schlenstedt C, Schwickert L, Scott K, Sharrack B, Taraldsen K, Troosters T, Vereijken B, Vogiatzis I, Yarnall AJ, Mazza C, Becker C, Rochester L, Puhan MA, Frei A. Walking-related digital mobility outcomes as clinical trial endpoint measures: Protocol for a scoping review. BMJ Open 2020, 10, e038704.
• Rehman RZU, Del Din S, Shi JQ, Galna B, Lord S, Yarnall AJ, Guan Y, Rochester L. Comparison of walking protocols and gait assessment systems for machine learning based classification of Parkinson’s disease. Sensors 2019, 19(24), 5363.
• King E, O'Brien J, Donaghy P, Williams-Gray CH, Lawson RA, Morris CM, Barnett N, Olsen K, Martin-Ruiz C, Burn DJ, Yarnall AJ, Taylor JP, Duncan GW, Khoo TK, Thomas A. Inflammation in Mild Cognitive Impairment due to Parkinson’s disease, Lewy Body disease and Alzheimer’s disease. International Journal of Geriatric Psychiatry 2019, 34(8), 1244-1250.
• Morris R, Yarnall AJ, Hunter H, Taylor JP, Baker MR, Rochester L. Noninvasive vagus nerve stimulation to target gait impairment in Parkinson's disease. Movement Disorders 2019, 34(6), 918-919.
• Durcan R, Wiblin L, Lawson RA, Khoo TK, Yarnall AJ, Duncan GW, Brooks DJ, Pavese N, Burn DJ. Prevalence and duration of non‐motor symptoms in prodromal Parkinson's disease. European Journal of Neurology 2019, 26(7), 979-985.
• Stuart S, Lawson RA, Yarnall YA, Nell J, Alcock L, Duncan DW, Khoo TK, Barker RA, Rochester L, Burn DJ. Pro‐Saccades Predict Cognitive Decline in Parkinson's Disease: ICICLE‐PD . Movement Disorders 2019, 34(11), 1690-1698.
• Rehman RZU, Del Din S, Guan Y, Yarnall AJ, Shi JQ, Rochester L. Selecting Clinically Relevant Gait Characteristics for Classification of Early Parkinson’s Disease: A Comprehensive Machine Learning Approach. Scientific Reports 2019, 9, 17269.
• Buckley C, Alcock L, Mc Ardle R, Rehman RZU, Del Din S, Mazzà C, Yarnall A, Rochester L. The role of movement analysis in diagnosing and monitoring neurodegenerative conditions: Insights from gait and postural control. Brain Sciences 2019, 9(2), 34.
• Sleeman I, Lawson RA, Yarnall AJ, Duncan GW, Johnston F, Khoo TK, Burn DJ. Urate and homocysteine: predicting motor and cognitive changes in newly diagnosed Parkinson’s disease. Journal of Parkinson's Disease 2019, 9(2), 351-359.
• Clegg BJ, Duncan GW, Khoo TK, Barker RA, Burn DJ, Yarnall AJ, Lawson RA. Categorising visual hallucinations in early Parkinson's disease. Journal of Parkinson's Disease 2018, 8(3), 447-453.
• Gravell R, Duncan GW, Khoo TK, Burn DJ, Sayer AA, Barker RA, Lawson RA, Yarnall AJ. Multimorbidity predicts quality of life but not motor severity in early Parkinson's disease. Journal of Parkinson's Disease 2018, 8(4), 511-515.
• Pantall A, Suresparan P, Kapa L, Morris R, Yarnall A, Del Din S, Rochester L. Postural dynamics are associated with cognitive decline in Parkinson's disease. Frontiers in Neurology 2018, 9, 1044.
• Bohnen NI, Yarnall AJ. Emerging non-invasive therapeutic approaches targeting hypocholinergic neural systems in Parkinson's disease. Neural Regeneration Research 2023, 18(4), 809-810.
• Hamilton CA, Frith J, Donaghy PC, Barker SAH, Durcan R, Lawley S, Barnett NA, Firbank M, Roberts G, Taylor JP, Allan LM, O'Brien JT, Yarnall AJ, Thomas AJ. Assessment of autonomic symptoms may assist with early identification of mild cognitive impairment with Lewy bodies. International Journal of Geriatric Psychiatry 2022, 37(4).
• Hamilton CA, Frith J, Donaghy PC, Barker SAH, Durcan R, Lawley S, Barnett NA, Firbank M, Roberts G, Taylor JP, Allan LM, O'Brien J, Yarnall AJ, Thomas AJ. Blood pressure and heart rate responses to orthostatic challenge and Valsalva manoeuvre in mild cognitive impairment with Lewy bodies. International Journal of Geriatric Psychiatry 2022, 37(5).
• Bohnen NI, Yarnall AJ, Weil RS, Moro E, Moehle MS, Borghammer P, Bedard M-A, Albin RL. Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches. The Lancet Neurology 2022, 21(4), 381-392.
• Mikolaizak AS, Rochester L, Maetzler W, Sharrack B, Demeyer H, Mazza C, Caulfield B, Garcia-Aymerich J, Vereijken B, Arnera V, Miller R, Piraino P, Ammour N, Gordon MF, Troosters T, Yarnall AJ, Alcock L, Gassner H, Winkler J, Klucken J, Schlenstedt C, Watz H, Kirsten A-M, Vogiatzis I, Chynkiamis N, Hume E, Megaritis D, Nieuwboer A, Ginis P, Buckley E, Brittain G, Comi G, Leocani L, Helbostad JL, Johnsen LG, Taraldsen K, Blain H, Driss V, Frei A, Puhan MA, Polhemus A, de Basea MB, Gimeno E, Hopkinson NS, Buttery SC, Hausdorff JM, Mirelman A, Evers J, Neatrour I, Singleton D, Schwickert L, Becker C, Jansen C-P. Connecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement–the Mobilise-D study protocol. PLoS ONE 2022, 17(10), e0269615.
• Cullinan RJ, Richardson SJ, Yarnall AJ, Burn DJ, Allan LM, Lawson RA. Documentation and Diagnosis of Delirium in Parkinson’s Disease. Acta Psychiatrica Scandinavica 2022, (ePub ahead of Print).
• Mc Ardle R, Del Din S, Morris R, Alcock L, Yarnall AJ, Burn DJ, Rochester L, Lawson RA. Factors Influencing Habitual Physical Activity in Parkinson’s Disease: Considering the Psychosocial State and Wellbeing of People with Parkinson’s and Their Carers. Sensors 2022, 22(3), 871.
• Gibbon JR, Parry SW, Witham MD, Yarnall A, Frith J. Feasibility, reliability and safety of self-assessed orthostatic blood pressure at home. Age and Ageing 2022, 51(7).
• Ray NH, Lawson RA, Martin SL, Sigurdsson HP, Wilson J, Galna B, Lord S, Alcock L, Duncan GW, Khoo TK, O'Brien JT, Burn DJ, Taylor JP, Rea R, Bergamino M, Rochester L, Yarnall AJ. Free-water imaging of the cholinergic basal forebrain and pedunculopontine nucleus in Parkinson’s disease. Brain 2022, 146(3), 1053–1064.
• Sigurdsson HP, Yarnall AJ, Galna B, Lord S, Alcock L, Lawson RA, Colloby SJ, Firbank MJ, Taylor JP, Pavese N, Brooks DJ, O'Brien JT, Burn DJ, Rochester L. Gait-related metabolic covariance networks at rest in Parkinson’s disease. Movement Disorders 2022, Epub ahead of print.
• Szwedo AA, Dalen I, Pedersen KF, Camacho M, Bäckström D, Forsgren L, Tzoulis C, Winder-Rhodes S, Hudson G, Liu G, Scherzer C, Lawson RA, Yarnall AJ, Williams-Gray CH, Macleod AD, Counsell CE, Tysnes OB, Alves G, Maple-Grødem J. GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study. Movement Disorders 2022, 37(5), 1016-1027.
• Rehman RZU, Guan Y, Shi JQ, Alcock L, Yarnall AJ, Rochester L, Del Din S. Investigating the Impact of Environment and Data Aggregation by Walking Bout Duration on Parkinson’s Disease Classification Using Machine Learning. Frontiers in Aging Neuroscience 2022, 14, 808518.