Staff Profile
Dr Amanda Robe
Research Project Manager
- Email: amanda.robe@ncl.ac.uk
- Personal Website: Translational and Clinical Research Institute
- Address: Faculty of Medical Sciences,
Wolfson Building , G20
Medical School
Framlington Place
Newcastle upon Tyne
NE2 4HH
My role as a Project Manager within the Faculty of Medical Sciences is varied, ranging from planning to ensure milestones are met, communication to all stakeholders, supporting clinical trials, financial management, co-ordinating outreach activities such as PPI activities, Sandpit events and ECR events.
As the projects are largely translational, a significant part of the role is liaising between the Trust, University, External parties, and the funder.
I currently support translational grants from MRC, NIHR i4i, BBSRC and have previously supported a CRUK grant.
I have a PhD in Immunobiology, and BSc in Applied Biology. I have gained relevant experience from working in drug development and clinical trials within the Pharmaceutical Industry, UK and US government led projects, and also various Project Management roles within academia.
- Jones DEJ, Robe A, Palmer J, Kirby JA. Adoptive transfer of self-PDC reactive T-cells into naive mice induces portal tract and bile duct changes characteristic of primary biliary cirrhosis (PBC). In: 41st Annual Meeting of the European Association for the Study of the Liver. 2006, Vienna, Austria: ELSEVIER SCIENCE BV.
- McHugh A, Robe AJ, Palmer JM, Jones DEJ. PDC-E3BP is not a dominant T-cell autoantigen in primary biliary cirrhosis. Liver International 2006, 26(4), 406-413.
- Robe AJ, Kirby JA, Jones DEJ, Palmer JM. A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 2005, 41(5), 1106-1112.
- Robe AJ, Kirby JA, Jones DEJ, Palmer JM. A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 2005, 41(5), 1106-1112.
- Robe AJ, Palmer JM, Kirby JA, Jones DEJ. Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process. In: Gut: Annual Meeting of the British Society of Gastroenterology. 2004, Glasgow, UK: BMJ Group.
- Robe AJ, Palmer J, Kirby J, Jones D. Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process. In: Hepatology: 55th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). 2004, Boston, Massachusetts, USA: John Wiley & Sons, Inc.
- Palmer JM, Robe AJ, Burt AD, Kirby JA, Jones DEJ. Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 2004, 39(6), 1583-1592.
- Robe AJ, Palmer JM, Kirby JA, Bassendine MF, Jones DEJ. [abstract] Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC). Gut 2002, 50(s2), A116 abstract no. 428.
- Robe A, Palmer J, Kirby J, Jones D. Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC). In: Journal of Hepatology. 2002, Elsevier BV.
- Jones DEJ, Palmer JM, Robe A, Kirby JA. Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis. Autoimmunity 2002, 35(8), 537-544.
- Jones DE, Robe AJ, Palmer JM, Kirby JA. Exploration of the immunogenicity of the primary biliary cirrhosis autoantigen pyuvate dehydrogenase complex. Hepatology 2001, 34, 730.
- Robe AJ, Palmer JM, Kirby JA, Jones DE. No role for autoreactive antibody in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex, the autoantigen in primary biliary cirrhosis. In: Hepatology. 2001, John Wiley & Sons, Inc.
- Robe A, Palmer JM, Yeaman SJ, Jones DEJ. The E3BP (protein X) component of pyruvate dehydrogenase complex (PDC) is not a T-cell autoantigen in primary biliary cirrhosis (PBC). In: JOURNAL OF HEPATOLOGY. 2000.
- Jones DE, Robe AJ, Palmer JM, Yeaman SJ, Kirby JA. The role played by gender in breakdown of immune tolerance in experimental autoimmune cholangitis: A mouse model of primary biliary cirrhosis. In: HEPATOLOGY. 2000.
- Jones DEJ, Palmer JM, Bennett K, Robe AJ, Yeaman SJ, Robertson H, Bassendine MF, Burt AD, Kirby JA. Investigation of a mechanism for accelerated breakdown of immune tolerance to the primary biliary cirrhosis-associated autoantigen, pyruvate dehydrogenase complex. Laboratory Investigation 2002, 82(2), 211-219.
- Jones DEJ, Palmer JM, Burt AD, Walker C, Robe AJ, Kirby JA. Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex. Hepatology 2002, 36(3), 679-686.