Staff Profile

Introduction

I completed my PhD at Imperial College London identifying host genetic loci responsible for the outcome of Helicobacter pylori infection. After my PhD I remained at Imperial College and worked as a Research Assistant studying seasonal changes in the suppressive capacity of Tregs in hayfever sufferers. I moved to Newcastle University in 2006 as a Research Associate and have been working on the pathogenesis of rheumatoid arthritis ever since. In 2016 I became a Senior Research Associate.

Area of expertise

• Tolerance induction
• Biomarker development and disease pathogenesis in rheumatoid arthritis

Projects

Since coming to Newcastle I have been involved in a number of projects focusing on the development of biomarkers for the diagnosis of rheumatoid arthritis, in addition to development of novel immunotherapies for rheumatoid arthritis, with a particular interest in therapeutic tolerance induction.

Biomarker development

In collaboration with Professor John Isaacs and Dr Arthur Pratt, we have identified a potential transcriptional biomarker for the early diagnosis of seronegative rheumatoid arthritis. We have demonstrated that interleukin-6 and downstream STAT3 signalling are potential therapeutic targets in the early stages of clinical disease. We are currently investigating several biomarkers linked to this pathway to determine their diagnostic and theragnostic value in rheumatoid arthritis. In addition, we are investigating several proteins linked to the transcriptional biomarker to further understand the pathogenesis of rheumatoid arthritis.

Tolerogenic dendritic cells (AuToDeCRA)

The main project I having been working on, in collaboration with Professor John Isaacs and Dr Catharien Hilkens, is the development of autologous tolerogenic dendritic cells for the treatment of rheumatoid arthritis. This project culminated in a phase I clinical trial (AuToDeCRA study, funded by Arthritis Research UK). We are now embarking on a second clinical trial using autologous tolerogenic dendritic cells, which is focused on determining the best route of administration.

Rheumatoid arthritis pathogenesis (BIO-FLARE)

I am currently involved in a MRC funded Experimental Medicine Challenge grant investigating factors that are involved in disease flare in rheumatoid arthritis. This is a multi-centre grant held between Newcastle University, Glasgow University and the University of Birmingham. At Newcastle, in collaboration with Professor John Isaacs, Dr Arthur Pratt and Dr Catharien Hilkens, we are investigating the immune system contribution to disease flare.

Postgraduate teaching

• I currently supervise/co-supervise 7 PhD students
• I co-supervise MRes students on an annual basis

Undergraduate teaching

• I currently lead a number of seminar sessions for Biomedical Science and Dentistry undergraduate students
• I co-supervise BSc students on an annual basis

• Articles

  • Baker KF, McDonald D, Hulme G, Hussain R, Coxhead J, Swan D, Schulz AR, Mei HE, MacDonald L, Pratt AG, Filby A, Anderson AE, Isaacs JD. Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature Communications 2024, 15, 1063.
  • Brown PM, Anderson AE, Naamane N, Lendrem DW, Morgan AW, Isaacs JD, Pratt AG. Adenosine metabolic signature in circulating CD4+ T cells predicts remission in rheumatoid arthritis. RMD Open 2024, 10(1), e003858.
  • Isaacs JD, Brockbank S, Pedersen AW, Hilkens C, Anderson A, Stocks P, Lendrem D, Tarn J, Smith GR, Allen B, Casement J, Diboll J, Harry R, Cooles FAH, Cope AP, Simpson G, Toward R, Noble H, Parke A, Wu W, Clarke F, Scott D, Scott IC, Galloway J, Lempp H, Ibrahim F, Schwank S, Molyneux G, Lazarov T, Geissmann F, Goodyear CS, McInnes IB, Donnelly I, Gilmour A, Virlan AT, Porter D, Ponchel F, Emery P, El-Jawhari J, Parmar R, McDermott MF, Fisher BA, Young SP, Jones P, Raza K, Filer A, Pitzalis C, Barnes MR, Watson DS, Henkin R, Thorborn G, Fossati-Jimack L, Kelly S, Humby F, Bombardieri M, Rana S, Jia Z, Goldmann K, Lewis M, Ng S, Barbosa-Silva A, Tzanis E, Gallagher-Syed A, John CR, Ehrenstein MR, Altobelli G, Martins S, Nguyen D, Ali H, Ciurtin C, Buch M, Symmons D, Worthington J, Bruce IN, Sergeant JC, Verstappen SMM, Stirling F, Hughes-Morley A, Tom B, Farewell V, Zhong Y, Taylor PC, Buckley CD, Keidel S, Cuff C, Levesque M, Long A, Liu Z, Lipsky S, Harvey B, Macoritto M, Hong F, Kaymakcalan S, Tsuji W, Sabin T, Ward N, Talbot S, Padhji D, Sleeman M, Finch D, Herath A, Lindholm C, Jenkins M, Ho M, Hollis S, Marshall C, Parker G, Page M, Edwards H, Cuza A, Gozzard N, Pandis I, Rowe A, Capdevila FB, Loza MJ, Curran M, Verbeeck D, Dan Baker, Mela CM, Vranic I, Mela CT, Wright S, Rowell L, Vernon E, Joseph N, Payne N, Rao R, Binks M, Belson A, Ludbrook V, Hicks K, Tipney H, Ellis J, Hasan S, Didierlaurent A, Burny W, Haynes A, Larminie C, Harris R, Dastros-Pitei D, Carini C, Kola B, Jelinsky S, Hodge M, Maciejewski M, Ziemek D, Schulz-Knappe P, Zucht H-D, Budde P, Coles M, Butler JA, Read S. RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients. Scientific Data 2022, 9(1), 196.
  • Cooles FAH, Tarn J, Lendrem DW, Naamane N, Lin CMA, Millar B, Maney NJ, Anderson AE, Thalayasingam N, Diboll J, Bondet V, Duffy D, Barnes MR, Smith GR, Ng S, Watson D, Henkin R, Cope AP, Reynard LN, Pratt AG, Isaacs JD. Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming. Annals of the Rheumatic Diseases 2022, 81(9), 1214-1223.
  • Cooke F, Neal M, Wood MJ, de Vries IJM, Anderson AE, Diboll J, Pratt AG, Stanway J, Nicorescu I, Moyse N, Hiles D, Caulfield D, Dickinson AM, Blamire AM, Thelwall P, Isaacs JD, Hilkens CM. Fluorine labelling of therapeutic human tolerogenic dendritic cells for 19F-magnetic resonance imaging. Frontiers in Immunology 2022, 13(2022), 988667.
  • Vidal-Pedrola G, Naamane N, Cameron JA, Pratt AG, Mellor AL, Isaacs JD, Scheel-Toellner D, Anderson AE. Characterization of age-associated B cells in early drug-naïve rheumatoid arthritis patients. Immunology 2023, 168(4), 640-653.
  • Maney NJ, Lemos H, Barron-Millar B, Carey C, Herron I, Anderson AE, Mellor AL, Isaacs JD, Pratt AG. Pim Kinases as Therapeutic Targets in Early Rheumatoid Arthritis. Arthritis and Rheumatology 2021, 73(10), 1820-1830.
  • Rayner F, Anderson AE, Baker KF, Buckley CD, Dyke B, Fenton S, Filer A, Goodyear CS, Hilkens CMU, Hiu S, Kerrigan S, Kurowska-Stolarska M, Matthews F, McInnes I, Ng W-F, Pratt AG, Prichard J, Raza K, Siebert S, Stocken D, Teare MD, Young S, Isaacs JD. BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study. BMC Rheumatology 2021, 5, 22.
  • Clark AD, Nair N, Anderson AE, Thalayasingam N, Naamane N, Skelton AJ, Diboll J, Barton A, Eyre S, Isaacs JD, Pratt AG, Reynard LN. Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci. Journal of Allergy and Clinical Immunology 2020, 145(5), 1438-1451.
  • Spiering R, Jansen MAA, Wood MJ, Fath AA, Eltherington O, Anderson AE, Pratt AG, van Eden W, Isaacs JD, Broere F, Hilkens CMU. Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis. Journal of Translational Medicine 2019, 17, 375.
  • Ridgley LA, Anderson AE, Maney NJ, Naamane N, Skelton AJ, Lawson CA, Emery P, Isaacs JD, Carmody RJ, Pratt AG. IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function. Frontiers in Immunology 2019, 10, 1535.
  • Anderson AE, Maney NJ, Nair N, Lendrem DW, Skelton AJ, Diboll J, Brown PM, Smith GR, Carmody RJ, Barton A, Isaacs JD, Pratt AG. Expression of STAT3-regulated genes in circulating CD4+ T cells discriminates rheumatoid arthritis independently of clinical parameters in early arthritis. Rheumatology 2019, 58(7), 1250-1258.
  • Ridgley LA, Anderson AE, Pratt AG. What are the dominant cytokines in early rheumatoid arthritis?. Current Opinion in Rheumatology 2018, 30(2), 207-214.
  • Cooles FAH, Anderson AE, Skelton A, Pratt AG, Kurowska-Stolarska MS, McInnes I, Hilkens CMU, Isaacs JD. Phenotypic and transcriptomic analysis of peripheral blood plasmacytoid and conventional dendritic cells in early drug naïve rheumatoid arthritis. Frontiers in Immunology 2018, 9, 755.
  • Thalayasingam N, Nair N, Skelton AJ, Massey J, Anderson AE, Clark AD, Diboll J, Lendrem DW, Reynard LN, Cordell HJ, Eyre S, Isaacs JD, Barton A, Pratt AG. CD4+ and B lymphocyte expression quantitative traits at rheumatoid arthritis risk loci in untreated early arthritis: implications for causal gene identification. Arthritis and Rheumatology 2018, 70(3), 361-370.
  • Anderson AE, Swan DJ, Wong OY, Buck M, Eltherington O, Harry RA, Patterson AM, Pratt AG, Reynolds G, Doran JP, Kirby JA, Isaacs JD, Hilkens CM. Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4⁺ T-cells partly via TGF-β1. Clinical & Experimental Immunology 2017, 187(1), 113-123.
  • Khamri W, Abeles RD, Hou TZ, Anderson AE, El-Masry A, Triantafyllou E, Bernsmeier C, Larsen FS, Singanayagam A, Kudo N, Possamai LA, Lebosse F, Auzinger G, Bernal W, Willars C, Weston CJ, Lombardi G, Wendon J, Thursz M, Antoniades CG. Increased Expression of Cytotoxic T-Lymphocyte−Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure. Gastroenterology 2017, 153(1), 263-276.e8.
  • Bell GM, Anderson AE, Diboll J, Reece R, Eltherington O, Harry RA, Fouweather T, MacDonald C, Chadwick T, McColl EM, Dunn J, Dickinson AM, Hilkens CMU, Isaacs JD. Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis. Annals of the Rheumatic Diseases 2017, 76(1), 227-234.
  • Lord P, Spiering R, Aguillón JC, Anderson AE, Appel S, Benitez-Ribas D, ten-Brinke A, Broere F, Cools N, Cuturi MC, Diboll J, Geissler EK, Giannoukakis N, Gregori S, van-Ham SM, Lattimer S, Marshall L, Harry RA, Hutchinson JA, Isaacs JD, Joosten I, van-Kooten C, López-Díaz-de-Cerio A, Nikolic T, Barbaros-Oral H, Sofronic-Milosavljevic L, Ritter T, Riquelme P, Thomson AW, Trucco M, Vives-Pi M, Martinez-Caceres E, Hilkens CM. Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies. PeerJ 2016, 4, 1-14.
  • Cooles FAH, Anderson AE, Drayton T, Harry RA, Diboll J, Munro L, Thalayasingham N, Ostor AJK, Isaacs JD. Immune reconstitution 20 years after treatment with alemtuzumab in a rheumatoid arthritis cohort: implications for lymphocyte depleting therapies. Arthritis Research & Therapy 2016, 18, 302.
  • Anderson AE, Pratt AG, Sedhom MA, Doran JP, Routledge C, Hargreaves B, Brown PB, LeCao KA, Isaacs JD, Thomas R. IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis. Annals of the Rheumatic Diseases 2016, 75, 466-473.
  • McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G. Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23. Genome Biology 2016, 17, 212.
  • Masca NGD, Hensor EMA, Cornelius VR, Buffa FM, Marriott HM, Eales JM, Messenger MP, Anderson AE, Boot C, Bunce C, Goldin RD, Harris J, Hinchliffe RF, Junaid H, Kingston S, Martin-Ruiz C, Nelson CP, Peacock J, Seed PT, Shinkins B, Staples KJ, Toombs J, Wright AKA, Dawn Teare M. RIPOSTE: a framework for improving the design and analysis of laboratory-based research. eLife 2015, 4(MAY), 1-45.
  • Purvis HA, Anderson AE, Young DA, Isaacs JD, Hilkens CMU. A Negative Feedback Loop Mediated by STAT3 Limits Human Th17 Responses. Journal of Immunology 2014, 193(3), 1142-1150.
  • Anderson AE, Lorenzi AR, Pratt A, Wooldridge T, Diboll J, Hilkens CM, Isaacs JD. Immunity 12 years after alemtuzumab in RA: CD5+ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses. Rheumatology 2012, 51(8), 1397-1406.
  • Brodlie M, McKean MC, Johnson GE, Anderson AE, Hilkens CM, Fisher AJ, Corris PA, Lordan JL, Ward C. Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease. European Respiratory Journal 2011, 37(6), 1378-1385.
  • Purvis HA, Stoop JN, Mann J, Woods S, Kozijn AE, Hambleton S, Robinson JH, Isaacs JD, Anderson AE, Hilkens CMU. Low-strength T-cell activation promotes Th17 responses. Blood 2010, 116(23), 4829-4837.
  • Harry RA, Anderson AE, Isaacs JD, Hilkens CM. Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis. Annals of the Rheumatic Diseases 2010, 69(11), 2042-2050.
  • Lorenzi A, Morgan TA, Anderson A, Catterall J, Patterson AM, Foster HE, Isaacs JD. Thymic function in juvenile idiopathic arthritis. Annals of the Rheumatic Diseases 2009, 68(6), 983-900.
  • Anderson AE, Mackerness KJ, Aizen M, Carr VA, Nguyen D, Du Pre F, Durham SR, Robinson DS. Seasonal changes in suppressive capacity of CD4 CD25 T cells from patients with hayfever are allergen-specific and may result in part from expansion of effector T cells among the CD25 population. Clinical & Experimental Allergy 2009, 39(11), 1693-1699.
  • Vila J, Isaacs JD, Anderson AE. Regulatory T cells and autoimmunity. Current Opinion in Hematology 2009, 16(4), 274-279.
  • Anderson AE, Swan DJ, Sayers BL, Harry RA, Patterson AM, von Delwig A, Robinson JH, Isaacs JD, Hilkens CM. LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells. Journal of Leukocyte Biology 2009, 85(2), 243-250.
  • Anderson AE, Isaacs JD. Tregs and rheumatoid arthritis. Acta Reumatológica Portuguesa 2008, 33(1), 17-33.
  • Anderson AE, Sayers BL, Haniffa MA, Swan DJ, Diboll J, Wang XN, Isaacs JD, Hilkens CMU. Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells. Journal of Leukocyte Biology 2008, 84(1), 124-133.
  • Khamri W, Worku ML, Anderson AE, Walker MM, Hawgood S, Reid KBM, Clark HW, Thursz MR. Helicobacter infection in the surfactant protein D-deficient mouse. Helicobacter 2007, 12(2), 112-123.
  • Anderson AE, Worku ML, Khamri W, Bamford KB, Walker MM, Thursz MR. TLR9 polymorphisms determine murine lymphocyte responses to Helicobacter: Results from a genome-wide scan. European Journal of Immunology 2007, 37(6), 1548-1561.

• Authored Book

  • Hilkens CMU, Diboll J, Cooke F, Anderson AE. In vitro generation of human tolerogenic monocyte-derived dendritic cells. New York, NY: Humana/Springer, 2023.

• Conference Proceedings (inc. Abstracts)

  • Pratt AG, Massey J, Anderson AE, Nair N, Diboll J, Skelton A, Lendrem DW, Reynard LN, Cordell HJ, Eyre S, Barton A, Isaacs JD. Identification of novel expression quantitative trait loci in CD4+ T cells of untreated early arthritis patients. In: 36th European Workshop for Rheumatology Research. 2016, York: BMJ Group.
  • Cooles FAH, Anderson AE, Hilkens C, Isaacs JD. The Interferon Gene Signature in Early Rheumatoid Arthritis Demonstrates No Significant Association with Disease Activity. In: 2015 ACR/ARHP Annual Meeting. 2015, San Francisco, CA, USA: Wiley.
  • Pratt AG, Anderson AE, Nair N, Massey J, Diboll J, Skelton A, Hargreaves B, Routledge C, Lendrem D, Brown P, Barton A, Isaacs JD. The Importance of IL-6-STAT₃ Mediated Activation of Circulating CD4⁺ T Cells in the Pathogenesis of Early Seronegative Rheumatoid Arthritis: A Validation Study. In: Rheumatology 2015. 2015, Manchester, UK: Oxford University Press.
  • Pratt AG, Anderson AE, Lendrem DW, Skelton A, Massey J, Nair N, Diboll J, Hargreaves B, Brown PM, Barton A, Isaacs JD. STAT3-regulated gene expression in circulating CD4+ T cells discriminates RA patients independently of clinical parameters in early arthritis: a validation study. In: 2015 ACR/ARHP Annual Meeting. 2015, San Francisco, CA.
  • Khamri W, Anderson AE, Abeles RD, Auzinger G, Bernal W, Willars C, Robinson JH, Lombardi G, Thursz MR, Wendon J, Antoniades CG. Adaptive Immune Reponses in ALF. In: 2nd Digestive Disorders Federation Conference. 2015, London, UK: BMJ Publishing Group.
  • Anderson AE, Pratt AG, Sedhom M, Nair N, Massey J, Routledge C, Hargreaves B, Brown P, Barton A, Isaacs JD, Thomas R. Phospho-STAT1/3 measurement in circulating CD4+T-cells as a diagnostic tool in early autoantibody-negative rheumatoid arthritis. In: British Society for Immunology Annual Congress. 2014, Brighton, UK: Wiley-Blackwell Publishing.
  • Anderson AE, Pratt AG, Sedhom M, Nair N, Massey J, Routledge C, Hargreaves B, Brown P, Barton A, Isaacs JD, Thomas R. Phospho-STAT1/3 and Gene Expression Measurement in Circulating CD4⁺ T Cells As Diagnostic Tools in Early Autoantibody-Negative Rheumatoid Arthritis. In: ACR/ARHP Annual Meeting. 2014, Boston, MA, USA: John Wiley & Sons, Inc.
  • Anderson A, Routledge C, Isaacs J, Pratt A. Investigation of interleukin-6-driven STAT3 signalling in circulating lymphocytes of patients with early rheumatoid arthritis as a route to biomarker discovery. In: Spring Meeting for Clinician Scientists in Training. 2014, London, UK: Elsevier.
  • Anderson AE, Pratt AG, Hargreaves B, Routledge C, Doran JP, Mawson P, Isaacs JD. IL-6 Driven Stat3 Phophorylation in Circulating Lymphocytes is Specifiv for CD4⁺ T Cells in Early Rheumatoid Arthritis. In: European Workshop for Rheumatology Research. 2014, Lisbon, Portugal: BMJ Publishing Group.
  • Bell G, Anderson A, Harry R, Diboll J, McColl E, Dickinson A, Hilkens C, Isaacs JD. Autologous tolerogenic dendritic cells in rheumatoid and inflammatory arthritis. In: European Workshop for Rheumatology Research. 2014, Lisbon, Portugal: BMJ Publishing Group Ltd.
  • Bell G, Anderson AE, Diboll J, Harry R, McColl E, Dickinson A, Hilkens C, Isaracs JD. Autologous Tolerogenic Dendritic Cells for Rheumatoid and Inflammatory Arthritis. In: ACR/ARHP Annual Meeting. 2014, Boston, MA, USA: Wiley-Blackwell Publishing Ltd.
  • Patsalidou M, Anderson A, Krippner-Heidenreich A. An unconventional anti-inflammatory role for TNF recpetor (TNFR)1 in tregs: TNFR1 and 2 differetnialy modulate FOXP3+ TREG function. In: European Workshop for Rheumatology Research. 2014, Lisbon, Portugal: BMJ Publishing Group.
  • Anderson AE, Routledge C, Mawson P, Isaacs JD, Pratt AG. Interleukin-6 Driven STAT3 Phosphorylation In Circulating Lymphocytes Is Specific For CD4⁺ T Cells In Early Rheumatoid Arthritis. In: Arthritis & Rheumatism 2013 Annual Meeting. 2013, San Diego, CA, USA: John Wiley & Sons, Inc.
  • Anderson AE, Routledge C, Mawson P, Isaacs JD, Pratt AG. Interleukin-6 driven STAT3 phosphorylation in circulating lymphocytes is specific for CD4 T cells in early rheumatoid arthritis. In: American College of Rheumatology. 2013, San Diego, California, USA. In Press.
  • Bell G, Anderson A, Diboll J, Harry R, McColl E, Dickinson A, Hilkens C, Isaacs J. Autologous Tolerogenic Dendritic Cells In Rheumatoid and Inflammatory Arthritis. In: Arthritis & Rheumatism 2013 Annual Meeting. 2013, San Diego, CA, USA: John Wiley & Sons, Inc.
  • Purvis H, Anderson AE, Hilkens CMU. Human T helper 17 responses: the effect of T-cell density. In: European Congress of Immunology. 2012, Glasgow, UK: Wiley-Blackwell.
  • Bell GM, Anderson AE, Harry RA, Stoop JN, Hilkens CM, Isaacs J, Dickinson A, McColl E. Autologous tolerogenic dendritic cells in rheumatoid arthritis. In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
  • Purvis HA, Anderson AE, Hilkens CMU. Human Th17 responses: the effect of T-cell density. In: Immunology: Annual Congress of the British Society for Immunology. 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
  • Purvis HA, Stoop JN, Mann J, Woods S, Kozijn AE, Hambleton S, Robinson JH, Isaacs JD, Anderson AE, Hilkens CMU. Low strength T-cell activation promotes Th17 responses. In: IImmunology: Annual Congress of the British Society for Immunology. 2010, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
  • Anderson AE, Sayers BL, Swan DJ, Isaacs JD, Hilkens CM. Tolerogenic dendritic cell therapy for rheumatoid arthritis. In: BSR Annual Meeting and BHPR Spring Meeting. 2008, Liverpool: Oxford University Press.
  • Morgan TA, Lorenzi A, Anderson A, Catteral J, Patterson AM, Foster HE, Isaacs J. Thymic function in juvenile idiopathic arthritis. In: Rheumatology: Annual Meeting of the British Society Rheumatology/Spring Meeting of British Health Professional in Rheumatology. 2008, Liverpool, UK: Oxford University Press.
  • Harry RA, Anderson AE, Raftery G, Wooldridge T, Isaacs JD, Hilkens CM. Development of clinical-grade tolerogenic dendritic cells for the treatment of rheumatoid arthritis. In: BSR Annual Meeting and BHPR Spring Meeting. 2008, Liverpool: Oxford University Press.
  • Anderson AE, Sayers B, Diboll J, Isaacs JD, Hilkens CM. Tolerogenic dendritic cells differentially modulate naïve and memory CD4⁺ T cells. In: 6th Global Arthritis Research Network (GARN) Meeting. 2007, Zurich, Switzerland: Arthritis Research & Therapy: BioMed Central Ltd.

• Letters

  • Cooles FAH, Anderson AE, Lendrem DW, Norris J, Pratt AG, Hilkens CMU, Isaacs JD. The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy. Journal of Allergy and Clinical Immunology 2017, 141(1), 445-448.e4.
  • Pratt AG, Anderson AE, Carmody RJ, Isaacs JD. Bcl-3 in CD4+ T Cell–Mediated Rheumatoid Arthritis Pathogenesis: Comment on the Article by Meguro et al. Arthritis and Rheumatology 2016, 68(3), 770-771.

• Reviews

  • Williams KC, Gault A, Anderson AE, Stewart CJ, Lamb CA, Speight RA, Rajan N, Plummer R, Pratt AG. Immune-related adverse events in checkpoint blockade: Observations from human tissue and therapeutic considerations. Frontiers in Immunology 2023, 14, 1122430.
  • Cooles FA, Isaacs JD, Anderson AE. Treg Cells in Rheumatoid Arthritis: An Update. Current Rheumatology Reports 2013, 15(9), 1-9.