BACKGROUND

A Chartered Statistician with a PhD in statistical epidemiology, I use complex longitudinal data and advanced statistical techniques to understand how health outcomes unfold over time. My principal area of technical interest relates to statistical methods that are applicable to complex longitudinal data that have the capacity to identify temporal trends and how factors impact/shape those trends. My mathematical expertise centres on methodology used to analyse longitudinal continuous and categorical data and microsimulation.

RESEARCH PORTFOLIO

1. Understanding pathways to disability and dependency in older people;
2. Understanding how disability is shaped by exposures to risk factors across the life-course and drivers of health inequality;
3. Developing disability risk prediction methodology;
4. Using microsimulation to project future prevalence and incidence of health outcomes;
5. Methods of calculating healthy life expectancy;
6. Causes of the male-female disability survival paradox.

VISION

To understand:

1. Ways in which age-related functional decline can be compressed to the shortest possible window before death, leading to better quality of life for older people by compressing their period of dependency.
2. The specific pathways through which biology, disease, lifestyle factors and sociodemographics interact across the life-course to shape health trajectories.

• Davies LE, Spiers G, Kingston A, Todd A, Adamson J, Hanratty B. Adverse Outcomes of Polypharmacy in Older People: Systematic Review of Reviews. Journal of the American Medical Directors Association (JAMDA) 2020, 21(2), 181–187.
• Barker R, Stocker R, Russell S, Roberts A, Kingston A, Adamson J, Hanratty B. Distribution of the National Early Warning Score (NEWS) in care home residents. Age and Ageing 2020, 49(1), 141-145.
• Wittenberg R, Hu B, Jagger C, Kingston A, Knapp M, Comas-Herrera A, King D, Rehill A, Banerjee S. Projections of care for older people with dementia in England: 2015 to 2040. Age and Ageing 2020, 49(2), 264–269.
• Mendonça N, Kingston A, Granic A, Jagger C. Protein intake and transitions between frailty states and to death in very old adults: the Newcastle 85+ study. Age and Ageing 2020, 49(1), 32–38.
• Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppala I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanche H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze J-F, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylha M, Kahonen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimaki T, Lieb W, Lyytikainen L-P, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine J-M, Rotter JI, Sebastiani P, Smith J, Sorensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications 2019, 10(1), 3669.
• Mendonça N, Kingston A, Granic A, Hill TR, Mathers JC, Jagger C. Contribution of protein intake and its interaction with physical activity to transitions between disability states and to death in very old adults: the Newcastle 85+ Study. European Journal of Nutrition 2019, ePub ahead of Print.
• Spiers G, Matthews FE, Moffatt S, Barker R, Jarvis H, Stow D, Kingston A, Hanratty B. Does older adults’ use of social care influence their healthcare utilisation? A systematic review of international evidence. Health & Social Care in the Community 2019, 27(5), e651-e662.
• Keeble E, Parker SG, Arora S, Neuburger J, Duncan R, Kingston A, Hanratty B, Jagger C, Robinson L, Kirkwood T. Frailty, hospital use and mortality in the older population: findings from the Newcastle 85+ study. Age and ageing 2019, 48(6), 797-802.
• Spiers G, Matthews FE, Moffatt S, Barker R, Jarvis H, Stow D, Kingston A, Hanratty B. Impact of social care supply on healthcare utilisation by older adults: A systematic review and meta-analysis. Age and Ageing 2019, 48(1), 57-66.
• Wittenberg R, Knapp M, Hu B, Comas-Herrera A, King D, Rehill A, Shi C, Banerjee S, Patel A, Jagger C, Kingston A. The costs of dementia in England. International Journal of Geriatric Psychiatry 2019, 34(7), 1095-1103.
• Kingston A, Comas-Herrera A, Jagger C. Forecasting the care needs of the older population in England over the next 20 years: estimates from the Population Ageing and Care Simulation (PACSim) modelling study. The Lancet Public Health 2018, 3(9), e447-e455.
• Gore PG, Kingston A, Johnson GR, Kirkwood TBL, Jagger C. New horizons in the compression of functional decline. Age and Ageing 2018, 47(6), 764-768.
• Kingston A, Robinson L, Booth H, Knapp M, Jagger C, for the MODEM project. Projections of multi-morbidity in the older population in England to 2035: estimates from the Population Ageing and Care Simulation (PACSim) model. Age and Ageing 2018, 47(3), 374-380.
• Mendonça N, Granic A, Hill TR, Siervo M, Mathers JC, Kingston A, Jagger C. Protein intake and disability trajectories in the very old: The Newcastle 85+ Study. Journal of the American Geriatrics Society 2018, 67(1), 50-56.
• Kingston A, Wohland P, Wittenberg R, Robinson L, Brayne C, Matthews FE, Jagger C. Is late-life dependency increasing or not? A comparison of the Cognitive Function and Ageing Studies (CFAS). The Lancet 2017, 390(10103), 1676-1684.
• Kingston A, Jagger C. Review of methodologies of cohort studies of older people. Age and Ageing 2017, 47(2), 215-219.
• Duncan R, Kingston A, Stephan B, Birrell F, Kirkwood T, Jagger C. Influence of Joint Pain on the Incidence and Progression of Disability in the Very Old: The Newcastle 85+ Study. In: Rheumatology 2016. 2016, Glasgow: Oxford University Press.
• Pearce SHS, Razvi S, Yadegarfar ME, Martin-Ruiz C, Kingston A, Collerton J, Visser TJ, Kirkwood TB, Jagger C. Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+Study. Journal of Clinical Endocrinology & Metabolism 2016, 101(11), 4385-4394.
• Brittain KR, Kingston A, Davies K, Collerton J, Robinson AL, Kirkwood T, Bond J, Jagger C. An investigation into the patterns of loneliness and loss in the oldest old – Newcastle 85+ Study. Ageing and Society 2015.
• Gore PG, Kingston A, Jagger C. Health and disability - Vulnerability in daily activities. In: Dr Susan Davidson and Phil Rossall, ed. Improving later life. Vulnerability and resilience in older people. London, UK: Age UK, 2015, pp.86.
• Duncan R, Francis RM, Jagger C, Kingston A, McCloskey E, Collerton J, Robinson L, Kirkwood TBL, Birrell F. Magnitude of fragility fracture risk in the very old – are we meeting their needs? The Newcastle 85+ Study. Osteoporosis International 2015, 26(1), 123-130.
• Duncan R, Francis RM, Jagger C, Kingston A, McCloskey E, Collerton J, Robinson L, Kirkwood TBL, Birrell F. Magnitude of fragility fracture risk in the very old-are we meeting their needs? The Newcastle 85+Study. Osteoporosis International 2015, 26(1), 123-130.
• Martin-Ruiz CM, Baird D, Roger L, Boukamp P, Krunic D, Cawthon R, Dokter MM, vanderHarst P, Bekaert S, deMeyer T, Roos G, Svenson U, Codd V, Samani NJ, McGlynn L, Shiels PG, Pooley KA, Dunning AM, Cooper R, Wong A, Kingston A, von Zglinicki T. Reproducibility of telomere length assessment: an international collaborative study. International Journal of Epidemiology 2015, 44(5), 1673-1683.
• Martin-Ruiz CM, Baird D, Roger L, Boukamp P, Krunic D, Cawthon R, Dokter MM, Van der Harst P, Bekaert S, De Meyer T, Roos G, Svenson U, Codd V, Samani NJ, Mcglynn L, Shiels PG, Pooley KA, Dunning AM, Cooper R, Wong A, Kingston A, Von Zglinicki T. Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic. International Journal of Epidemiology 2015, 44(5), 1739-1741.
• Siervo M, Prado C, Hooper L, Munro A, Collerton J, Davies K, Kingston A, Mathers JC, Kirkwood TBL, Jagger C. Serum osmolarity and haematocrit do not modify the association between the impedance index (Ht²/Z) and total body water in the very old: The Newcastle 85+Study. Archives of Gerontology and Geriatrics 2015, 60(1), 227-232.
• Kingston A, Davies K, Collerton J, Robinson l, Duncan R, Kirkwood TBL, Jagger C. The enduring effect of education - socioeconomic differences in disability trajectories from age 85 years in the Newcastle 85+ Study. Archives of Gerontology and Geriatrics 2015, 60(3), 405-411.
• Siervo M, Kingston A, Kirkwood T, Mathers J, Collerton J, Davies K, Jagger C. Anthropometric measures of adiposity as predictors of disability-free life expectancy and all-cause mortality in the very old. In: Gerontological Society of America 67th Annual Scientific Meeting. 2014, Washington, DC: Oxford University Press.
• Davies K, Kingston A, Robinson L, Hughes J, Hunt JM, Barker SAH, Edwards J, Collerton J, Jagger C, Kirkwood TBL. Improving Retention of Very Old Participants in Longitudinal Research: Experiences from the Newcastle 85+ Study. PLoS ONE 2014, 9(10), e108370.
• Wiley L, Ashok D, Martin-Ruiz C, Talbot DCS, Collerton J, Kingston A, Davies K, Chinnery PF, Catt M, Jagger C, Kirkwood TBL, von Zglinicki T. Reactive Oxygen Species Production and Mitochondrial Dysfunction in White Blood Cells Are Not Valid Biomarkers of Ageing in the Very Old. PLoS ONE 2014, 9(3), e91005.
• Kingston A, Davies K, Collerton J, Robinson L, Duncan R, Bond J, Kirkwood TBL, Jagger C. The Contribution of Diseases to the Male-Female Disability-Survival Paradox in the Very Old: Results from the Newcastle 85+ Study. PLoS ONE 2014, 9(2), e88016.
• Anstey KJ, Kingston A, Kiely KM, Luszcz MA, Mitchell P, Jagger C. The influence of smoking, sedentary lifestyle and obesity on cognitive impairment-free life expectancy. International Journal of Epidemiology 2014, 43(6), 1874-1883.
• Wassall RR, Kingston A, Jagger C, Collerton J, Bond J, Kirkwood T, Steele J. Trajectories in Oral Health and Tooth Loss. In: 92 General Session & Exhibition of the IADR Africa/Middle East Regional Meeting. 2014, Cape Town, South Africa.
• Kingston A, Robinson L, Kirkwood T, Collerton J, Davies K, Jagger C. Trajectories of disability in the very old: the effect of early, mid and late life socioeconomic status. In: Gerontological Society of America 67th Annual Scientific Meeting. 2014, Washington DC: Oxford University Press.
• Collerton J, Kingston A, Yousaf F, Davies K, Kenny A, Neely D, Martin-Ruiz C, MacGowan G, Robinson L, Kirkwood TBL, Keavney B. Utility of NT-proBNP as a rule-out test for left ventricular dysfunction in very old people with limiting dyspnoea: the Newcastle 85+Study. BMC Cardiovascular Disorders 2014, 14, 128.
• Newton L, Gibson G, Pritchard G, Finch T, Brittain K, Kingston A, Robinson L. Assistive technologies in caring for the oldest old. In: 7th NIHR Trainee Conference 2013. 2013, Leeds: National Institute for Health Research.
• Robinson L, Gibson G, Kingston A, Newton L, Pritchard G, Finch T, Brittain K. Assistive technologies in caring for the oldest old: a review of current practice and future directions. Aging Health 2013, 9(4), 365-375.
• Jagger C, Chiatti C, Kingston A, Collerton J, Davies K, Martin-Ruiz C, von Zglinicki T, Kirkwood T. SOCIOECONOMIC DIFFERENCES IN TELOMERE LENGTH IN THE VERY OLD: RESULTS FROM THE NEWCASTLE 85+STUDY. In: GERONTOLOGIST. 2013, JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA: OXFORD UNIV PRESS INC.
• Jefferis JM, Taylor JP, Collerton J, Jagger C, Kingston A, Davies K, Kirkwood T, Clarke MP. The association between diagnosed glaucoma and cataract and cognitive performance in very old people: Cross sectional findings from the Newcastle 85+ cohort study. Ophthalmic Epidemiology 2013, 20(2), 82–88.
• Collerton J, Yousaf F, Kingston A, Kenny A, Davies K, Robinson L, Kirkwood T, Keavney B. Cardiac dysfunction among the community dwelling very old. In: GSA 65th Annual Scientific Meeting. 2012, San Diego, California, USA: Oxford University Press.
• Jagger C, Bond J, Robinson L, Kingston A, Collerton J, Davies K, von Zglinicki T, Kirkwood T. Gender differences in the association between self-rated health and mortality: Results from the Newcastle 85+ Study. In: GSA 65th Annual Scientific Meeting. 2012, San Diego, California, USA: Oxford University Press.
• Brittain K, Jagger C, Kingston A, Collerton J, Davies K, Robinson L, Kirkwood T, Bond J. Loneliness in the very old: Patterns over time. In: GSA 65th Annual Scientific Meeting. 2012, San Diego, California, USA: Oxford University Press.
• Kingston A, Collerton J, Davies K, Bond J, Robinson L, Jagger C. Losing the Ability in Activities of Daily Living in the Oldest Old: A Hierarchic Disability Scale from the Newcastle 85+ Study. PLoS One 2012, 7(2), e31665.
• Kingston A, Bond J, Collerton J, Davies K, Robinson L, Kirkwood T, Jagger C. Modelling the impact of chronic diseases on disability-free life expectancy in the very old. In: GSA 65th Annual Scientific Meeting. 2012, San Diego, California, USA: Oxford University Press.
• Yousef F, Collerton J, Kingston A, Kenny A, Davies K, Jagger C, Robinson L, Kirkwood TBL, Keavney B. Prevalence of left ventricular dysfunction in a UK community sample of very old people: the Newcastle 85+ study. Heart 2012, 98(19), 1418-1423.
• Jefferis JM, Collerton J, Taylor JP, Jagger c, Kingston A, Davies K, Kirkwood T, Clarke MP. The impact of visual impairment on mini-mental state examination scores in the Newcastle 85+ study. Age and Ageing 2012, 41(4), 565-568.
• Collerton J, Kingston A, Bond J, Davies K, Eccles MP, Jagger C, Kirkwood TBL, Newton JL. The Personal and Health Service Impact of Falls in 85 Years Olds: Cross-Sectional Findings from the Newcastle 85+ Cohort Study. PLoS One 2012, 7(3), e33078.
• Kingston A, Davies K, Jagger C, Collerton J, Kirkwood T, Bond J, Robinson L. Why do older men die and older women become disabled? The role of dementia on transitions to severe disability and death in the very old. In: GSA 65th Annual Scientific Meeting. 2012, San Diego, California, USA: Oxford University Press.
• Martin Ruiz C, Jagger C, Kingston A, Collerton J, Catt M, Davies K, Dunn M, Hilkens C, Keavney B, Pearce S, den Elzen W, Talbot D, Wiley L, Bond J, Mathers J, Eccles M, Robinson L, James O, Kirkwood T, von Zglinicki T. Assessment of a large panel of candidate biomarkers of ageing in the Newcastle 85+ study. Mechanisms of Ageing and Development 2011, 132(10), 496-502.
• Jagger C, Collerton JC, Davies K, Kingston A, Robinson LA, Eccles MP, von Zglinicki T, Martin-Ruiz C, James OFW, Kirkwood TBL, Bond J. Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs. BMC Geriatrics 2011, 11, 21.
• Collerton J, Kingston A, Davies K, Bond J, Eccles M, Jagger C, Kirkwood T, Newton J. Falls are common in 85 year olds, are associated with physical and psychological morbidity, and have marked consequences for health services: Results from the Newcastle 85+ Study. In: Age and Ageing: British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
• Yousaf F, Collerton J, Kenny A, Kirkwood T, Jagger C, Kingston A, Keavney B. High prevalence of undiagnosed cardiac dysfunction in the oldest old: Findings from the Newcastle 85+ Study. In: Heart: Annual Conference of the British Cardiovascular Society (BCS). 2011, Manchester, UK: BMJ Group.
• Collerton J, Yousaf F, Kingston A, Davies K, Jagger C, Kenny A, Kirkwood T, Keavney B. High prevalence of undiagnosed cardiac dysfunction in the oldest old: Findings from the Newcastle 85+ Study. In: Age and Ageing: British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
• Duncan R, Francis RM, Collerton J, Davies K, Jagger C, Kingston A, Kirkwood T, Robinson L, Birrell F. Prevalence of arthritis and joint pain in the oldest old - Findings from the Newcastle 85+ Study. In: Age and Ageing: British Geriatrics Society Spring Meeting. 2011, Liverpool: Oxford University Press.
• Duncan R, Francis RM, Collerton J, Davies K, Jagger C, Kingston A, Kirkwood T, Robinson L, Birrell F. Prevalence of arthritis and joint pain in the oldest old: findings from the Newcastle 85+ Study. Age and Ageing 2011, 40(6), 752-755.
• Kirkwood T, Martin-Ruiz C, Jagger C, Collerton J, Kingston A, von Zglinicki T. Biomarkers of ageing and their relationship to disability and cognition [abstract]. Gerontologist 2010, 50, 375.
• Jagger C, Collerton J, Robinson L, Eccles MP, Kingston A, von Zglinicki T, Kirkwood T, Bond J. Disability and dependency: How much care is in the community? [abstract]. Gerontologist 2010, 50(s1), 375-375.
• Collerton J, Davies K, Jagger C, Kingston A, Bond J, Eccles MP, Robinson L, Kirkwood T. High levels of disease and health service use but good functional status and self-rated health are found in 85 year olds [abstract]. Gerontologist 2010, 50(s1), 375.
• Collerton J, Davies K, Jagger C, Kingston A, Bond J, Eccles M, Robinson L, Martin-Ruiz C, Von Zglinicki T, James O, Kirkwood T. Health and disease in 85 year olds: Baseline findings from the Newcastle 85+ cohort study. British Medical Journal 2009, 339, b4904.