Staff Profile
Background
My original training was in bacterial genomics and gene-regulation. After working in cancer cell biology, I became particularly interested in the mechanisms by which nutrients, and specifically short-chain fatty acids, regulate cell death pathways and how these processes are distinct from the actions of chemotherapeutics. I was appointed as lecturer in nutrition at Sheffield Univesity. Through this role I developed a wider understanding of nutrition research approaches, I have been The LEad for Cellular and Molecular nutrition, and later Trustee and honorary pogrammes officer of The Nutrition Society.
I joined The Human Nutrition Research Centre at Newcastle University in March 2021, continuing and expanding my focus in nutrition and cancer.
Publications
See my profile on GoogleScholar here
External & National Roles
I am editor in chief of the Journal of Nutritional Science.
I am a member of the WCRF grant panel.
I am president elect of the Nutrition Society.
Research Interests
My longstanding interests are in the role of nutrition in prevention of cancers, and in particular how best to prevent progression of transformed cells and prevent recurrent neoplasms. My work is multidisciplinary in nature and includes molecular and cellular approaches, in silico, as well as human studies and secondary data analyses.
Particular areas of interest are in improving outcomes across the care pathway from screening to therapy to living beyond cancer, including improving understanding how nutrients may modify risk of recurrence.
Publications
See my profile on GoogleScholar here
PGR Supervision
I have supervised over 20 PhD/MD/MPhil to successful completion.
I am currently co-supervising several MD and PhD students:
Anna Fretwell - Imrpoving dietary advice provision for people living with and beyond colorectal cancer
Jiemin Fan - analysing the interrelationship betweem fibre intake, bile acids and the microbiome
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Articles
- Orange ST, Brown MC, Hallsworth K, Malcomson FC, Corfe B, Tweedie C, Cresti N, Cain H, Court P, Willson C, Ross K, Mathers JC, Saxton JM, Sharp L, Smith SG. Co-development of a programme to improve physical activity support for women after breast cancer treatment: a pre-protocol for PURE-EX . NIHR Open Research 2025, 5(3).
- Malcomson FC, Louca P, Nelson A, Willis ND, McCallum I, Xie L, Ouwehand AC, Stowell JD, Preston T, Morrison DJ, Kelly SB, Michael Bradburn D, Belshaw NJ, Johnson IT, Corfe BM, Stewart CJ, Mathers JC. Effects of non-digestible carbohydrates on gut microbiota and microbial metabolites: a randomised, controlled dietary intervention in healthy individuals. British Journal of Nutrition 2024, 132(11), 1433-1445.
- Fretwell A, Dobson C, Orange ST, Corfe B. Diet and physical activity advice for colorectal cancer survivors: Critical synthesis of public-facing guidance. Supportive Care in Cancer 2024, 32, 609.
- Shannon OM, Townsend R, Malcomson FC, Matu J, Griffiths A, Jennings A, Ward N, Papier K, Best N, French C, Scheelbeek P, Kim C, Ochieng B, Jay F, Shepherd K, Corfe B, Fairley A, McEvoy CT, Minihane A-M, Sim YJ, Stevenson E, Gregory S. Adherence to the Eatwell Guide and population and planetary health: A Rank Prize Forum report. Nutrition Bulletin 2024, 49(1), 108-119.
- Williams CE, Williams EA, Corfe BM. Vitamin D supplementation in people with IBS has no effect on symptom severity and quality of life: results of a randomised controlled trial. European Journal of Nutrition 2022, 61(1), 299-308.
- Tuttiett ER, Green DJ, Stevenson EJ, Hill TR, Corfe BM, Williams EA. Short-Term Protein Supplementation Does Not Alter Energy Intake, Macronutrient Intake and Appetite in 50–75 Year Old Adults. Nutrients 2021, 13(5), 1711.
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Note
- Corfe BM, Smith T, Heslehurst N, Nightingale JM, Kenneally S, Williams S, Moore JB. Long overdue: Undergraduate nutrition education for medical students. British Journal of Nutrition 2023, 129(6), 1009-1010.
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Review
- Fretwell A, Louca P, Cohoon G, Sakellaropoulou A, Henriques Caetano MDP, Koullapis A, Orange ST, Malcomson FC, Dobson C, Corfe BM. Still too little evidence: the role of diet in colorectal cancer survivorship - a systematic review. Critical Reviews in Food Science and Nutrition 2024, ePub ahead of Print.