Staff Profile

Current Role

I work in the pharmacology group where I have lab management duties covering chromatography and mass spectrometry equipment. I also lead on method development and perform clinical trial analysis. Our lab and data systems are GCP/GCLP regulated due to our involvement in clinical research.

Background

Prior to joining the University, my professional background was in the biotech and pharma industries, where I worked as a Senior Bioanalytical Scientist performing regulated PK/PD/TK studies. I also have experience working in histopathology, performing cancer diagnostics using protein and genetic biomarker assays, such as immunohistochemistry and in-situ hybridisation.

Qualifications

• BSc (Hons), Biological Sciences, Lancaster University
• MSc, Molecular Genetics and Diagnostics, University of Nottingham
• Currently working towards a PhD in Cancer Pharmacology at Newcastle University

Research

I develop and validate LC-MS methods for the quantitation of chemotherapy drugs in biological samples. These methods are used in research studies across clinical trials, pharmacokinetics, therapeutic drug monitoring and toxicology.

Current Lab Equipment - Newcastle Cancer Centre Pharmacology Group (NCCPG)

LC-MS/MS

• Shimadzu Prominence LC20 - Sciex API4000 MS
• Agilent 1260 Infinity LC - Sciex Q-TRAP 5500 MS
• Agilent 1260 Infinity LC - Agilent 6460 MS

HPLC-DAD

• Agilent 1260 Infinity II LC - Agilent 1100 Series Diode Array Detector (x2)

Atomic Absorption Spectroscopy

• Agilent 280FS-AA

Project Supervision

I supervise undergraduate BSc students and postgraduate MRes students during their research projects in the pharmacology group.