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Staff Profile

Jason Powell

MRC Clinician Scientist and Honorary Consultant Paediatric ENT Surgeon

  • Email: jason.powell@ncl.ac.uk
  • Address: Translational and Clinical Research Institute
    Faculty of Medical Sciences
    Newcastle University
    M2.108 2nd Floor Leech Building
    Newcastle upon Tyne
    NE2 4HH
Background


Introduction

I am a MRC Clinician Scientist in the Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University. I work clinically as an Honorary Consultant in Paediatric Otolaryngology-Head and Neck Surgery at the Great North Children's Hospital (GNCH) and the Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust.

My research focuses primarily on infectious disease and inflammatory disorders within the airway and middle ear cleft, particularly in children. This work spans bench to bedside; including laboratory-based studies, translational clinical studies and population based work.



Previous positions

Fellow, Division of Pediatric Otolaryngology-Head and Neck Surgery, B.C. Children’s Hospital, University of British Columbia, Vancouver, Canada (2022 - 2023)

NIHR Clinical Lecturer and Speciality Training Registrar in Otolaryngology-Head and Neck Surgery, Newcastle University (2018 - 2022)


Qualifications

MBBS, MRes, MRCS, DO-HNS, PhD, FRCS (ORL-HNS)


Awards and Honours

Colledge Family Memorial Fellowship Fund, Royal College of Surgeons of England, 2022

Susanna Leighton Fellowship, British Association for Paediatric Otolaryngology, 2017

ENTUK Annual Meeting Presentation Prize, 2017

David Howard Prize, British Laryngological Association, 2015

British Rhinological Society Presentation Prize, 2014


External links

Hospital profile

Google Scholar

ResearchGate

Linkedin

ORCiD


SG01 subglottic epithelial cell line available via:

cancertools.org

ximbio.com

phe-culturecollections.org.uk


Research

Outline

My research program focuses primarily on understanding the role of innate immunity in infectious and inflammatory diseases within the airway and middle ear cleft, particularly in children. This work spans bench to bedside;

Laboratory: leukocyte biology, advanced cell culture models, delivery of gene vectors, mucin biology, microbiome, proteomics, transcriptomics and metabolomics.

Translational research: clinical studies, large database analysis, qualitative research, epidemiological studies.


Funding

2023 Medical Research Council, Clinician Scientist Fellowship, (PI) £1.9M

2021 Wellcome Trust/Newcastle University, Small Grant Scheme, (Co-I) £10K

2021 Barbour Foundation, Research Support Funds, (PI) £2K

2021 Newcastle Hospitals Charity, Scientific Committee Grant, (PI) £5K

2020 Action Medical Research, Research Training Fellowship, (Co-I) £241K

2020 Royal National Institute for Deaf People, Flexi Grant, (Co-I) £6K

2019 Academy of Medical Sciences, Starter Grants for Clinical Lecturers, (PI) £29K

2019 Great North Children’s Hospital Foundation Fund, (PI) £25K

2018 Wellcome Trust/Newcastle University, Small Grant Scheme, (PI) £10K

2017 Wellcome Trust, Laboratory Consumables Grant, (Co-I) £5K

2015 Wellcome Trust, Clinical Research Training Fellowship, (PI) £220K


Commercial outputs

SG01 subglottic epithelial cell line available via:

cancertools.org

ximbio.com

phe-culturecollections.org.uk




Teaching

Certificate in Clinical Education, Association for Medical Education in Europe (AMEE)

I have delivered numerous teaching sessions and lectures to medical students and postgraduates on Otolaryngology-Head and Neck Surgery.

I have also supervised several researchers in the laboratory and clinical setting, including MRes and PhD students, post-doctoral researchers and clinical academic trainees.

Publications