The work in our group aims at identifying gene mutation(s) causing immune dysregulation in those primary immunodeficient patients by next generation exome sequencing. I am engaged on several projects, mainly I work on a project that identifies a novel genetic cause of Omenn's syndrome, a rare primary immunodeficiency. We hope that by investigating novel causes of primary immunodeficiencies will improve our understanding of how human immunity works, and thus improve clinical outcomes.

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