Staff Profile

Introduction

I am an NIHR Academic Clinical Lecturer based in the Translational and Clinical Research Institute at Newcastle University and my research interests are in paediatric cystic fibrosis, specifically the investigation of dysfunctional epithelial ion transport in the cystic fibrosis airway. 

Qualifications

MBBS, MRes, MRCPCH, PhD 

Roles and responsibilities

NIHR Reviewer Development Scheme (2020 to present)

UK Cystic Fibrosis Medical Association Paediatric Trainee Representative (2019 to present)

Newcastle University Ethics Committee Reviewer (2019 to present)

Editorial board member ‘Beat Asthma’ online resource (2017)

ALSG Newborn Life Support Instructor (2015 to present)

Awards

Academy of Medical Sciences Starter Grant for Clinical Lecturers (2021)

Wellcome Trust Institutional Strategic Support Fund (2019)

Wellcome Trust ISSF Broadening Our Horizons Scheme, North American Cystic Fibrosis Conference (2019)

Wellcome Trust Clinical Research Training Fellowship (2016 to 2018)

British Paediatric Respiratory Society Travel Award, European Cystic Fibrosis Society Conference (2019)

Best presentation, Institute of Cellular Medicine Directors’ Day, Newcastle University (2017)

I am an NIHR ACL in Paediatric Respiratory Medicine and my research interests in cystic fibrosis and the development of relevant airway models to investigate the impact of dysfunctional airway epithelial ion transport in the cystic fibrosis airway. 

In my clinical work, I am involved in teaching medical students and doctors in aspects of paediatrics and paediatric respiratory medicine. I am a certified ALSG Newborn Life Support Instructor.

I have supervised students within the university including during summer studentships, an MD project and have been involved in teaching laboratory skills to undergraduate and postgraduate students. 

• Haq IJ, Althaus M, Gardner AI, Yeoh HY, Joshi U, Saint-Criq V, Verdon B, Townshend J, O'Brien C, Ben-Hamida M, Thomas M, Bourke S, van der Sluijs P, Braakman I, Ward C, Gray MA, Brodlie M. Clinical and molecular characterisation of the R751L-CFTR mutation. American Journal of Physiology Lung Cellular and Molecular Physiology 2021, 320(2), L288-L300.
• Bain R, Cosgriff R, Zampoli M, Elbert A, Burgel P-R, Carr SB, Castaños C, Colombo C, Corvol H, Faro A, Goss CH, Gutierrez H, Jung A, Kashirskaya N, Marshall BC, Melo J, Mondejar-Lopez P, de Monestrol I, Naehrlich L, Padoan R, Dolores Pastor-Vivero M, Rizvi S, Salvatore M, Vicente Ribeiro Ferreira da Silva Filho L, Brownlee KG, Haq IJ, Brodlie M. Clinical characteristics of SARS-CoV-2 infection in children with cystic fibrosis: An international observational study. Journal of Cystic Fibrosis 2021, 20(1), 25-30.
• Gardner AI, Haq IJ, Simpson AJ, Becker KA, Gallagher J, Saint-Criq V, Verdon B, Mavin E, Trigg A, Gray MA, Koulman A, McDonnell MJ, Fisher AJ, Kramer EL, Clancy JP, Ward C, Schuchman EH, Gulbins E, Brodlie M. Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine 2020, 202(8), 1133-1145.
• Zainal Abidin N, Gardner AI, Robinson H, Haq IJ, Thomas MF, Brodlie M. Trends in nontuberculous mycobacteria infection in children and young people with cystic fibrosis. Journal of Cystic Fibrosis 2021, 20(5), 737-741.
• Haq IJ, Parameswaran MC, Abidin NZ, Socas A, Gonzalez-Ciscar A, Gardner AI, Brodlie M. Modulator therapies for cystic fibrosis. Paediatrics and Child Health 2019, 29(4), 151-157.
• Saint-Criq V, Haq IJ, Gardner AI, Garnett JP, Ward C, Brodlie M, Gray MA. Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells. Journal of Visualized Experiements 2019, (148), e59815.
• Zainal Abidin N, Haq IJ, Gardner AI, Brodlie M. Ataluren in cystic fibrosis: development, clinical studies and where are we now?. Expert Opinion on Pharmacotherapy 2017, 18(13), 1363-1371.
• Haq IJ, Battersby AC, Eastham K, McKean M. Community acquired pneumonia in children. BMJ 2017, 356, j686.
• Haq I, Harris C, Taylor J, McKean MC, Brodlie M. Should we use montelukast in wheezy children?. Archives of Disease in Childhood 2017, 102(11), 997-998.
• Haq IJ, Gardner A, Brodlie M. A multifunctional bispecific antibody against Pseudomonas aeruginosa as a potential therapeutic strategy. Annals of Translational Medicine 2016, 4(1), 12.
• Haq IJ, Gray MA, Garnett JP, Ward C, Brodlie M. Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets. Thorax 2016, 71(3), 284-287.
• Brodlie M, Haq IJ, Roberts K, Elborn JS. Targeted therapies to improve CFTR function in cystic fibrosis. Genome Medicine 2015, 7(1), 101.
• Haq I, Gopalakaje S, Fenton AC, McKean MC, O'Brien C, Brodlie M. The evidence for high flow nasal cannula devices in infants. Paediatric Respiratory Reviews 2014, 15(2), 124-134.
• Haq IJ, Steinberg LJ, Hoenig M, van der Burg M, Villa A, Cant AJ, Middleton PG, Gennery AR. GvHD-associated cytokine polymorphisms do not associate with Omenn syndrome rather than T-B- SCID in patients with defects in RAG genes. Clinical Immunology 2007, 124(2), 165-169.