Staff Profile
Dr Neil Rajan
Senior Lecturer and Honorary Consultant Dermatologist
- Email: neil.rajan@ncl.ac.uk
- Telephone: +44 (0) 191 241 8813
- Address: Translational and Clinical Research
Newcastle University
International Centre for Life
Central Parkway
Newcastle upon Tyne
NE1 3BZ
Dr. Neil Rajan M.D. PhD is a principal investigator and honorary consultant dermatologist. He started his own lab group with funding from the Wellcome Trust and is passionate about translational research in rare genetic skin disease. He has personally secured more than £1.6M for rare genetic skin disease research and has received 9 national awards for his work. He was recently awarded the Whimster Prize by the BAD and Honorary Membership to the Hungarian Dermatological Society for his work on CYLD cutaneous syndrome.
His basic science research programme is coupled with the delivery of early phase clinical trials in rare disease, an exemplar of which is the TRAC study in CYLD cutaneous syndrome, where he was chief investigator. He has 69 peer reviewed publications, and has papers in Lancet Oncology, Oncogene, JAMA Dermatology, Nature Communications and Science.
Patient partnership is central to his work. He developed a new adult dermatogenetics service in Newcastle and works with patients to design patient relevant clinical trial outcomes. His research group engages the public and patients at events such as Rare Disease Day at the International Centre for Life in Newcastle.
He has demonstrated that a detailed focus on a rare debilitating disease, in his case CYLD cutaneous syndrome, can lead to more effective care for those affected but also contribute to our deeper understanding of normal physiology, the influence of individual genes and the pathways they inhabit and the potential for targeted therapy.
Area of expertise
- Dermatogenetics
- Skin Cancer
Twitter @derm_scientist
My basic science research programme is coupled with the delivery of early phase clinical trials in rare disease, an exemplar of which is the TRAC study in CYLD cutaneous syndrome, where I was chief investigator. To enhance my ability to deliver rare disease skin research, I collaborate with clinicians and scientists including:
- Sir John Burn (Newcastle, UK) – CYLD genetic testing
- Alan Ashworth (UCSF, USA) – CYLD function
- Vivek Malhotra (CRG, Barcelona) – Tumour matrix biology
- Yutaka Shimomura (Yamaguchi University, Japan ) - Rare skin disease
- 2018-2019: Newcastle Biomedical Research Centre (BRC) Grant - Scratching the surface”: Employing gene expression signatures in pigmented skin lesions to develop point of care diagnostics in the elderly. £122,362
- 2017-2020: British Skin Foundation PhD Studentship – Targeting non-canonical NF-kB signalling in CYLD defective tumours 2017. £85,000
- 2015-2016: BRC - Leveraging rare mosaic skin disease to inform pathogenic mutation discovery in psoriasis. £75,220
- 2013-2016: Health Innovation Challenge Fund - Topical tropomyosin kinase (TRK) inhibitor as a treatment for inherited CYLD defective skin tumours. £396,980
- 2013-2015: Newcastle Healthcare Charity: Gene expression profiling of inherited and sporadic cutaneous hair follicle tumours. £32,000
- 2012-2018: Wellcome Trust Intermediate Clinical Fellowship 2012. £784,882
Leadership roles in research
- Chair of Informatics for the British Association of Dermatology Genetic Medicine group (2013–21). I have led the development and implementation of a Scottish rare genetic skin disease registry. Building on this, I currently lead the development of a UK wide register of genetic skin disease in partnership with Public Health England – National Congenital Anomalies and Rare disease registration service.
- Steering group member for the Skin Genomics England Clinical Interpretation Partnership for the 100,000-genome project (2017-21).
- Committee member of the British Society of Investigative Dermatology
Through 14 invited lectures at national/international meetings (e.g. Great Ormond Street, National Institute of Health (US), I have presented data on translational research that directly impacts on patient care. Selected:
- Stanford Dermatology Grand Rounds - "CYLD cutaneous syndrome"
- Findacure – “Repurposing and Rare Skin Disease Trials” - Rare Disease Day 2017
- Paediatric Oncology Branch, National Institute of Health, “Inherited cutaneous tumour syndromes: The CYLD story". 2015
Mentoring clinical trainees and scientists to recognise the importance of research to is critical for the development of future researchers in the NHS, which underpins excellent service delivery.
· I have mentored dermatology specialist trainees in a range skin genetics research projects, three of whom have won national prizes.
• Dr. Brown- 5 first author publications.
• Dr. Dubois - 6 first author publications.
• Dr. Brass - 1st prize at the dermatopathology meeting at the British Association of Dermatologists meeting.
· I have supervised as lead supervisor four non-clinical PhD students, four Masters students and one clinical MD student (2013-2019).
I have co-organised and chaired national/international conferences and meetings to train clinical trainees and non-clinical scientists in dermatology, paediatrics and genetics:
· World Congress of Dermatology 2019 – Inherited skin tumour symposium (Milan).
· British Association of Dermatologists Genetic Medicine meetings 2016-2021
· Genomics for Dermatology 2018, 2020 - Residential course at the Sanger, Cambridge.
· British Association of Dermatology Research Techniques course 2018, Institute of Genetic Medicine, Newcastle.
- Gault A, Anderson A, Plummer R, Stewart C, Pratt AG, Rajan N. Cutaneous immune‐related adverse events in patients with melanoma treated with checkpoint inhibitors. British Journal of Dermatology 2021, ePub ahead of print.
- Reynolds G, Vegh P, Fletcher J, Poyner EFM, Stephenson E, Goh I, Botting RA, Huang N, Olabi B, Dubois A, Dixon D, Green K, Maunder D, Engelbert J, Efremova M, Polański K, Jardine L, Jones C, Ness T, Horsfall D, McGrath J, Carey C, Popescu D-M, Webb S, Wang X-N, Sayer B, Park J-E, Negri VA, Belokhvostova D, Lynch MD, McDonald D, Filby A, Hagai T, Meyer KB, Husain A, Coxhead J, Vento-Tormo R, Behjati S, Lisgo S, Villani A-C, Bacardit J, Jones PH, O'Toole EA, Ogg GS, Rajan N, Reynolds NJ, Teichmann SA, Watt FM, Haniffa M. Developmental cell programs are co-opted in inflammatory skin disease. Science 2021, 371(6527), eaba6500.
- Loh A, Ho C, Muthias S, Venkatesh B, Bray A, Reversade B, Rajan N, Carney T. Huriez syndrome caused by a large deletion that abrogates the skin‐specific isoform of SMARCAD1. British Journal of Dermatology 2021, ePub ahead of print.
- Rajan N. Image gallery: first take a good picture, then tell a good story. British Journal of Dermatology 2021, 184(1), 1-1.
- Guckian J, Rajan N, Kibbi N. Incompletely excised keratinocyte carcinomas: more common than once thought?. British Journal of Dermatology 2021, 184(6), 991-991.
- Dobson-Stone C, Hallupp M, Shahheydari H, Ragagnin AMG, Chatterton Z, Carew-Jones F, Shepherd CE, Stefen H, Paric E, Fath T, Thompson EM, Blumbergs P, Short CL, Field CD, Panegyres PK, Hecker J, Nicholson G, Shaw AD, Fullerton JM, Luty AA, Schofield PR, Brooks WS, Rajan N, Bennett MF, Bahlo M, Landers JE, Piguet O, Hodges JR, Halliday GM, Topp SD, Smith BN, Shaw CE, McCann E, Fifita JA, Williams KL, Atkin JD, Blair IP, Kwok JB. CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis. Brain: A Journal of Neurology 2020, 143(3), 783-799.
- Muthiah S, Polubothu S, Husain A, Oliphant T, Kinsler VA, Rajan N. A mosaic variant in MAP2K1 is associated with giant naevus-spilus type congenital melanocytic naevus and melanoma development. British Journal of Dermatology 2020, 183(4), 760-761.
- Manam S, Oliphant T, Husain A, Rajan N. Basaloid follicular proliferations, brain tumours and SUFU. British Journal of Dermatology 2020, 183(5), e146-e146.
- Ghadiri SJ, Brennan P, Calonje E, Carmichael AJ, Rajan N. Co-inheritance of Naevoid Basal Cell Carcinoma Syndrome and Neurofibromatosis Type 1 associated with an exceptional spectrum of tumours. The British Journal of Dermatology 2020, 183(6), 1108-1110.
- Dubois A, Rajan N. CYLD Cutaneous Syndrome. University of Washington: GeneReviews® [Internet], 2020. Available at: https://www.ncbi.nlm.nih.gov/books/NBK555820/.
- Cook S, Wilson V, Ness J, Burn J, Husain A, Rajan N. Detection of genetic tumour predisposition syndromes using electronic health records. British Journal of Dermatology 2020, 183(5), 949-950.
- Pap EM, Farkas K, Szell M, Nemeth G, Rajan N, Nagy N. Identification of putative phenotype-modifying genetic factors associated with phenotypic diversity in Brooke-Spiegler syndrome. Experimental Dermatology 2020, 29(10), 1017-1020.
- Langtry J, Rajan N. Pre-emptive intra-auricular electrosurgical resurfacing of cylindromas to prevent conductive deafness in CYLD cutaneous syndrome. British Jounral of Dermatology 2020, 183(6), e188-e188.
- Kibbi N, Rajan N. Reading through genetic 'stop signs': a therapeutic strategy in genetic skin disease. British Journal of Dermatology 2020, 183(1), 11-11.
- Oyston LJ, Chatterton Z, Hallupp M, Rajan N, Kwok JB, Dobson-Stone C. Reply: CYLD variants in frontotemporal dementia associated with severe memory impairment in a Portuguese cohort. Brain 2020, 143(8), e68-e68.
- Shimomura Y, O'Shaughnessy RF, Rajan N. PLCD1 and pilar cysts. Journal of Investigative Dermatology 2019, 139(10), 2075-2077.
- Linos E, Rajan N, Ingram JR. BJD: a global dermatology journal serving the needs of its readers worldwide. British Journal of Dermatology 2019, 181(1), 3-4.
- Danilenko M, Hodgson K, Stones R, Husain A, Zangarini M, Veal G, Rajan N. Diverse assays from a single skin punch biopsy to assess topical drug intervention. British Journal of Dermatology 2019, 180(4), 937-938.
- Arefi M, Wilson V, Muthiah S, Zwolinski S, Bajwa D, Brennan P, Blasdale K, Bourn D, Burn J, Santibanez-Koref M, Rajan N. Diverse presentations of cutaneous mosaicism occur in CYLD cutaneous syndrome and may result in parent-to-child transmission. Journal of American Academy of Dermatology 2019, 81(6), 1300-1307.
- Davies HR, Hodgson K, Schwalbe E, Coxhead J, Sinclair N, Zou X, Cockell S, Husain A, Nik-Zainal S, Rajan N. Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome. Nature Communications 2019, 10, 4717.
- March OP, Lettner T, Klausegger A, Ablinger M, Kocher T, Hainzl S, Peking P, Lackner N, Rajan N, Hofbauer JP, Guttmann-Gruber C, Bygum A, Koller U, Reichelt J. Gene editing-mediated disruption of epidermolytic ichthyosis-associated KRT10 alleles restores filament stability in keratinocytes. Journal of Investigative Dermatology 2019, 139(8), 1699-1710.e6.
- Lovgren M-L, Rajan N, Joss S, Melly L, Porter M. Inherited desmoplastic trichoepitheliomas. Clinical and Experimental Dermatology 2019, 44(7), e238-e239.
- Muthiah S, Wu KCP, Rajan N. Public engagement lectures targeting prospective medical students: an opportunity for dermatology. Clinical and Experimental Dermatology 2019, 44(3), 355-356.
- Dubois A, Rannan-Eliya S, Husain A, Rajan N, Oliphant T. Squamous cell carcinomas in linear epidermal naevi. Clinical and Experimental Dermatology 2019, 44(2), 238-240.
- Brown S, Ahmed J, Zwolinski S, Brennan P, Rajan N. A novel link between keratoderma and cardiomyopathy: Contiguous gene deletion involving the desmoglein gene cluster. British Journal of Dermatology 2018, 178(1), 284-285.
- Brown SM, Arefi M, Stones R, Loo PS, Barnard S, Bloxham C, Stefanos N, Langtry JAA, Worthy S, Calonje E, Husain A, Rajan N. Inherited pulmonary cylindromas: Extending the phenotype of CYLD mutation carriers. British Journal of Dermatology 2018, 179(3), 662-668.
- Bajwa DS, Nasr B, Carmichael AJ, Rajan N. Milia: a useful clinical marker of CYLD mutation carrier status. Clinical and Experimental Dermatology 2018, 43(2), 193-195.
- Hoyle A, Davies K, Rajan N, Melly L. p63 and smooth muscle actin expression in low grade spiradenocarcinomas in a case of CYLD cutaneous syndrome. Journal of Cutaneous Pathology 2018, 45(10), 760-763.
- Martin RJ, Arefi M, Splitt M, Redford L, Moss C, Rajan N. Phacomatosis pigmentokeratotica and precocious puberty associated with HRAS mutation. British Journal of Dermatology 2018, 178(1), 289-291.
- Dubois A, Mestre T, Oliphant T, Husain A, Rajan N. Squamous cell carcinoma and multiple familial trichoepitheliomas: A recurrent association. Acta Dermato-Venereologica 2018, 98(9), 910-911.
- Danilenko M, Stamp E, Stocken DD, Husain A, Zangarini M, Cranston A, Stones R, Sinclair N, Hodgson K, Bowett SA, Roblin D, Traversa S, Plummer R, Veal G, Langtry JAA, Ashworth A, Burn J, Rajan N. Targeting tropomyosin receptor kinase in cutaneous CYLD defective tumors (TRAC): A randomised placebo-controlled early phase trial with pegcantratinib. JAMA Dermatology 2018, 154(8), 913-921.
- Brown S, Worthy SA, Langtry JAA, Rajan N. Tracking tumor kinetics in patients with germline CYLD mutations. Journal of the American Academy of Dermatology 2018, 79(5), 949-951.
- Danilenko M, Stones R, Rajan N. Transcriptomic profiling of human skin biopsies in the clinical trial setting: A protocol for high quality RNA extraction from skin tumours. Wellcome Open Research 2018, 3, 45.
- Zangarini M, Rajan N, Danilenko M, Berry P, Traversa S, Veal GJ. Development and validation of LC–MS/MS with in-source collision-induced dissociation for the quantification of pegcantratinib in human skin tumors. Bioanalysis 2017, 9(3), 279-288.
- Brown SM, Brennan P, Rajan N. Inherited skin tumour syndromes. Clinical Medicine Journal 2017, 17(6), 562-567.
- Dubois A, Alonso-Sanchez A, Bajaj V, Husain A, Rajan N. Multiple facial trichoepitheliomas and vulval cysts: Extending the phenotypic spectrum in CYLD cutaneous syndrome. JAMA Dermatology 2017, 153(8), 826-828.
- Cranston A, Stocken DD, Stamp E, Roblin D, Hamlin J, Langtry J, Plummer R, Ashworth A, Burn J, Rajan N. Tropomyosin Receptor Antagonism in Cylindromatosis (TRAC), an early phase trial of a topical tropomyosin kinase inhibitor as a treatment for inherited CYLD defective skin tumours: study protocol for a randomised controlled trial. Trials 2017, 18, 111.
- Dubois A, Hodgson K, Rajan N. Understanding Inherited Cylindromas Clinical Implications of Gene Discovery. Dermatologic Clinics 2017, 35(1), 61-71.
- Brown S, Ahmed J, Zwolinski S, Brennan P, Rajan N. A novel contiguous heterozygous deletion involving the desmoglein 2 and desmocollin 2 genes is associated with arrhythmogenic right ventricular cardiomyopathy. In: BAD/RCP Medical Dermatology Meeting. 2016, Royal College of Physicians, London: Wiley-Blackwell Publishing Ltd.
- Rajan N, Sinclair N, Nakai H, Shimomura Y, Natarajan S. A tale of two sisters: identical IL36RN mutations and discordant phenotypes. British Journal of Dermatology 2016, 174(2), 417-420.
- Brown S, Brass D, Rajan N, Oliphant T, Plummer R, Langtry J. Advanced basal cell carcinomas treated by vismodegib and Mohs micrographic surgery: does neoadjuvant treatment have a role?. In: British Association of Dermatologists 96th Annual Meeting. 2016, Birmingham, UK: Wiley-Blackwell.
- Dubois A, Arefi M, Splitt MP, Leech S, Natarajan S, Rajan N. Dry Skin and Blistering in Childhood. Clinical and Experimental Dermatology 2016, 41(7), 828-830.
- Rajan N, Brown S, Ward S, Hainsworth P, Hodgkinson P, Pieniazek P, Husain A, Plummer R. Mesenteric cysts in naevoid basal cell carcinoma syndrome: A mimic of metastatic disease. British Journal of Dermatology 2016, 174(3), 684-685.
- Whitaker S, Leech S, Taylor A, Splitt M, Natarajan S, Rajan N. Multifocal capillary malformations in an older, asymptomatic child with a novel RASA1 mutation. Clinical and Experimental Dermatology 2016, 41(2), 156-158.
- Rajan N, Andersson MK, Sinclair N, Fehr A, Hodgson K, Lord CJ, Kazakov DV, Vanecek T, Ashworth A, Stenman G. Overexpression of MYB drives proliferation of CYLD-defective cylindroma cells. The Journal of Pathology 2016, 239(2), 197-205.
- Rajan N, Andersson M, Sinclair N, Fehr A, Hodgson K, Lord C, Kazakov D, Vanecek T, Ashworth A, Stenman G. Overexpression of MYB drives proliferation of CYLD-defective cylindroma cells. In: European Society for Dermatological Research (ESDR) 2016 Annual Meeting. 2016, Munich, Germany: Nature Publishing Group.
- Brown S, Barnard S, Langtry J, Worthy SA, Bloxham C, Loo PS, Husain A, Rajan N. Pulmonary cylindromas in CYLD cutaneous syndrome. In: British Association of Dermatologists 96th Annual Meeting. 2016, Birmingham, UK: Wiley-Blackwell Publishing Ltd.
- Brown S, Worthy SA, Barnard S, Langtry J, Rajan N. Tracking tumour kinetics in patients with germline CYLD mutations. In: British Association of Dermatologists 96th Annual Meeting. 2016, Birmingham, UK: Wiley-Blackwell Publishing Ltd.
- Tang DYL, O'Shea S, Espinoza D, Rajan N, Carmichael A, Newton-Bishop JA. A second family with a telomerase reverse transcriptase (TERT) promoter gene mutation associated with melanomas. In: British Journal of Dermatology. 2015, Manchester, UK: Wiley-Blackwell.
- Dubois A, Wilson V, Bourn D, Rajan N. CYLD Genetic Testing for Brooke-Spiegler Syndrome, Familial Cylindromatosis and Multiple Familial Trichoepitheliomas. PLoS Currents: Evidence on Genomic Tests 2015, 7.
- Kazmierczyk K, Oliphant T, Rajan N, Lawrence C, Langtry J. Sebaceous carcinoma treated by Mohs micrographic surgery: a review of 14 cases. In: British Association of Dermatologists 95th Annual Meeting. 2015, Manchester, UK: Wiley-Blackwell Publishing Ltd.
- Koron S, Leech S, Taylor A, Splitt M, Natarajan S, Rajan N. A novel RASA1 mutation presenting with multiple cutaneous capillary malformations. In: 28th Annual Meeting of the British Society for Paediatric Dermatology. 2014, London: Wiley-Blackwell.
- Brass D, Rajan N, Oliphant TJ, Langtry JAA. Enucleation of cylindromas in Brooke-Spiegler syndrome: a novel surgical technique. In: Abstracts for the British Association of Dermatologists 94th Annual Meeting. 2014, Glasgow: Wiley-Blackwell.
- Rajan N, Sinclair N, Nakai H, Shimomura Y, Natarajan S. Heterozygote IL36RN mutations in a European case of early-onset generalized pustular psoriasis challenge the concept of private mutation. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle upon Tyne: Wiley-Blackwell.
- Tan HY, Kirkham N, Lovat P, Rajan N. Increased p62 expression in CYLD-defective tumours: indication of an autophagic dependency?. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle upon Tyne: Wiley-Blackwell.
- Rajan N, Brown S, Ward S, Pieniazek P, Hainsworth P, Douglas F, Husain A, Plummer R. Mesenteric cysts in Gorlin syndrome: a mimic of metastatic disease. In: Abstracts for the British Association of Dermatologists 94th Annual Meeting. 2014, Glasgow: Wiley-Blackwell.
- Rajan N, Elliott RJR, Smith A, Sinclair N, Swift S, Lord CJ, Ashworth A. The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate Notch signalling. Oncotarget 2014, 5(23), 12126-12140.
- Rajan N, Elliott R, Smith A, Sinclair N, Swift S, Lord C, Ashworth A. The Cylindromatosis gene product, CYLD, interacts with MIB2 to regulate Notch signalling. In: 44th Annual Meeting of the European Society for Dermatological Research. 2014, Copenhagen, Denmark: Nature Publishing Group.
- Rahim RR, Rajan N, Langtry JAA. Infiltrative Recurrent Eccrine Spiradenoma of the Anterior Neck Treated Using Mohs Micrographic Surgery. Dermatologic Surgery 2013, 39(11), 1711-1714.
- Rajan N, Elliot R, Clewes O, Mackay R, Reis-Filho JS, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A. Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours. Oncogene 2011, 30(41), 4243-4260.
- Rajan N, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A. Transition from cylindroma to spiradenoma in CYLD-defective tumours is associated with reduced DKK2 expression. Journal of Pathology 2011, 224(3), 309-321.
- Rajan N, Elliott R, Lord CJ, Burn J, Blum MS, Ashworth A. Advances in the development of new therapies for CYLD mutation carriers Targeting Trk. In: Journal of Medical Genetics. 2010, BMJ Publishing Group.
- Rajan N, Elliott R, Lord CJ, Burn J, Sieber-Blum M, Ashworth A. Advances in the development of new therapies for CYLD mutation carriers: Targeting Trk. In: British Society of Human Genetics Annual Conference. 2010, London, UK: BMJ Group.
- Rajan N, Elliott R, Lord C, Clewes O, Burn J, Sieber-Blum M, Ashworth A. Dysregulated tropomyosin receptor kinase (Trk) signalling in CYLD mutant tumours. In: 40th Annual Meeting of the European Society for Dermatological Research. 2010, Nature Publishing Group.
- Rajan N, Lord CJ, Clewes O, Burn J, Sieber-Blum M, Ashworth A. Dysregulated tropomyosin receptor kinase signalling in CYLDtrunc/trunc tumours. In: Annual Meeting of the British Society for Investigative Dermatology. 2010, Edinburgh, Scotland: British Journal of Dermatology.
- Rajan N, Wahie S, Seukeran D. Papulonodular eruption, proteinuria, and peripheral arthritis. Papulonodular dermal mucinosis (PDM) in systemic lupus erythematosus. Archives of Dermatology 2010, 146(7), 789-794.
- Rajan N, Gillinder K, Lord C, Langtry JAA, Burn J, Ashworth A, Chaudhury B, Sieber-Blum M. Unravelling cylindromas: insights into appendageal tumour patterning from patients with truncating CYLD mutations. In: 90th Annual Meeting of the British Association of Dermatologists. 2010, Manchester, UK: Wiley-Blackwell Publishing, Inc.
- Rajan N, Bourn D, Roberts C, Langtry JAA, Burn J. A review of seven UK pedigrees with CYLD mutations: clinical implications for mutation carriers. In: 89th Annual Meeting of the British Association of Dermatologists. 2009, Glasgow, UK: Wiley-Blackwell Publishing, Inc.
- Hiscutt E, Rajan N, Panter S, Natarajan S. Demonstration of gastrointestinal venous malformations in Blue Rubber Bleb Naevus Syndrome using capsule endoscopy. Journal of the European Academy of Dermatology and Venereology 2009, 23(3), 322-324.
- Rajan N, Trainer A, Burn J, Langtry J. Familial cylindromatosis and brooke-spiegler syndrome: A review of current therapeutic approaches and the surgical challenges posed by two affected families. Dermatologic Surgery 2009, 35(5), 845-852.
- Rajan N, Das S, Taylor A, Abinun M, Spencer D, Carmichael A. Idiopathic Infantile Pyoderma Gangrenosum with Stridor Responsive to Infliximab. Pediatric Dermatology 2009, 26(1), 65-69.
- Rajan N, Langtry JAA, Ashworth A, Roberts C, Chapman P, Burn J, Trainer AH. Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations: Implications for Disease Management and Tumor Induction. Archives of Dermatology 2009, 145(11), 1277-1284.
- Rajan N, Powell H, Langtry JAA, Carmichael A, Bourn D, Burn J. Two novel CYLD mutations associated with Brooke-Spiegler syndrome. In: 89th Annual Meeting of the British Association of Dermatologists. 2009, Glasgow, UK: Wiley-Blackwell Publishing, Inc.
- Rajan N, Langtry J, Chapman P, Trainer A, Burn J. Familial cylindromatosis, Brooke-Spiegler syndrome and multiple famililal trichoepithiliomas: Tumour mapping of 26 patients with CYLD mutations suggest androgen stimulation may play a role in tumourigenesis. In: 2008 Annual Meeting. 2008, Nature Publishing Group.
- Rajan N, Varma D, Chapman F, Langtry JA. Painful eye caused by basal cell carcinoma of the eyelid: Tumour enlargement resulting in trichiasis. Acta Dermato-Venereologica 2008, 88(1), 66.
- Rajan N, Langtry JAA. The punch and graft technique: a novel method of surgical treatment for chondrodermatitis nodularis helicis. British Journal of Dermatology 2007, 157(4), 744-747.
- Rajan N, Carmichael AJ, Bramble MG, Hudson M. Cutaneous xanthomatosis: a novel presentation of hypercholesterolaemia in primary sclerosing cholangitis. British Journal of Dermatology 2006, 155(1), 223-225.
- Rajan N, Langtry JA. Generalized exacerbation of psoriasis associated with imiquimod cream treatment of superficial basal cell carcinomas. Clinical and Experimental Dermatology 2006, 31(1), 140-141.
- Rajan N, Natarajan S. Impetignised eczema arising within a port-wine stain of the arm. Journal of the European Academy of Dermatology and Venereology 2006, 20(8), 1009-1010.
- Rajan N, Ryan J, Langtry JA. Squamous cell carcinoma arising within a facial port-wine stain treated by Mohs micrographic surgical excision. Dermatologic Surgery 2006, 32(6), 864-866.
- Rajan N, Carmichael AJ, McCarron BM. Human cowpox: presentation and investigation in an era of bioterrorism. Journal of Infection 2005, 51(3), e167-e169.
- Harbison J, Rajan N, James OFW, Ford G, Gibson GJ. Sleep apnoea in patients following stroke. In: Thorax. 1999, BMJ Group.