Staff Profile

Background

I am a member of the Evidence Synthesis Team in the Population Health Sciences Institute and the NIHR Innovation Observatory, where I lead the Information Programme. I am a member of the Innovation, Methodology and Application theme, the NIHR Methodology Incubator, and also the Older People and Frailty Policy Research Unit.

I have worked on systematic reviews for over ten years, both as information specialist and systematic reviewer.

My PhD looked at the use of evidence synthesis methods to optimise the use of complex behaviour change interventions, specifically interventions to reduce hazardous and harmful alcohol consumption. 

Qualifications

PhD "Evidence synthesis methods to inform decisions about complex behaviour change interventions in public health: brief alcohol interventions as a case study" Newcastle University, 2023

Postgraduate Diploma in Information and Library Studies, University of Northumbria

Honours Degree in Chemistry, University of Warwick

Previous positions

2012-2019 Research Associate, Institute of Health and Society, Newcastle University

2010-2012 Information Specialist/Research Fellow, Centre for Reviews and Dissemination

2003-2010  Information Specialist, Institute of Health and Society, Newcastle University

2001-2003 Trials Search Coordinator, Cochrane Injuries Group

1998-2001 Information Scientist, United Biscuits R&D Services

1995-1998 Senior Library Assistant (Science & Engineering), University of Wales Swansea Library

Research interests

I'm interested in methods of literature retrieval for systematic reviews, in research synthesis methods, and in the most appropriate methods and sources for horizon scanning as part of my Innovation Observatory role. 

I peer review for various journals including JMIR, Implementation Science, the Journal of Clinical Epidemiology, and Health Information and Libraries Journal. 

MSc in Public Health and Health Services Research - I contribute to and am previous module lead for the 'Introduction to systematic reviewing and critical appraisal' module of the Masters in Public Health.

• Articles

  • O'Keefe H, Rankin J, Wallace SA, Beyer F. Investigation of text‐mining methodologies to aid the construction of search strategies in systematic reviews of diagnostic test accuracy–a case study. Research Synthesis Methods 2023, 14(1), 79-98.
  • Kunonga TP, Spiers GF, Richmond C, Beyer FR, Bower P, Hanratty B, Craig D. Health interventions and the unseen impact on equality. The Lancet Healthy Longevity 2023, 4(1), E8-E9.
  • Kenny RPW, Millar EB, Adesanya A, Richmond C, Beyer F, Calderon C, Rankin J, Toledano M, Feychting M, Pearce MS, Craig D, Pearson F. The effects of radiofrequency exposure on male fertility and adverse reproductive outcomes: A protocol for two systematic reviews of human observational studies with meta-analysis. Environment International 2022, 158, 106968.
  • Al-Zubaidy M, Hogg HJ, Maniatopoulos G, Talks J, Teare MD, Keane PA, Beyer FR. Stakeholder Perspectives on Clinical Decision Support Tools to Inform Clinical Artificial Intelligence Implementation: Protocol for a Framework Synthesis for Qualitative Evidence. JMIR Research Protocols 2022, 11(4), e33145.
  • Kontogiannis V, Coughlan D, Javanbakht M, Kunonga P, Beyer F, Richmond C, Bryant A, Bajwa D, Ellis RA, Vale L. Optimal Surveillance Strategies for Early-Stage Cutaneous Melanoma Post Primary Tumour Excision: An Economic Evaluation. MDM Policy & Practice 2022, 7(1), 1-11.
  • Spiers GF, Kunonga TP, Stow D, Hall A, Kingston A, Williams O, Beyer F, Bower P, Craig D, Todd C, Hanratty B. Factors associated with unmet need for support to maintain independence in later life: a systematic review of quantitative and qualitative evidence. Age and Ageing 2022, 51(10), 1-11.
  • Spiers GF, Liddle J, Kunonga TP, Whitehead IO, Beyer F, Stow D, Welsh C, Ramsay SE, Craig D, Hanratty B. What are the consequences of caring for older people and what interventions are effective for supporting unpaid carers? A rapid review of systematic reviews. BMJ Open 2021, 11(9), e046187.
  • Currie CC, Araujo-Soares V, Stone SJ, Beyer F, Durham J. Promoting Regular Dental Attendance in Problem-Orientated Dental Attenders: A Systematic Review of Potential Interventions. Journal of Oral Rehabilitation 2021, 48(10), 1183-1191.
  • Vale L, Kunonga P, Coughlan D, Kontogiannis V, Astin M, Beyer F, Richmond C, Wilson D, Bajwa D, Javanbakht M, Bryant A, Akor W, Craig D, Lovat P, Labus M, Nasr Batoul, Cunliffe T, Hinde H, Shawgi M, Saleh D, Royle P, Steward P, Lucas R, Ellis R. Optimal surveillance strategies for Patients with stage 1 cutaneous melanoma post primary tumour excision: three systematic reviews and an economic model. Health Technology Assessment 2021, 25(64).
  • Spiers GF, Kunonga TP, Hall A, Beyer F, Boulton E, Parker S, Bower P, Craig D, Todd C, Hanratty B. Measuring frailty in younger populations: a rapid review of evidence. BMJ Open 2021, 11, e047051.
  • McGowan LJ, Joyes EC, Adams EA, Coyte A, Gavin R, Richmond C, Shabaninejad H, Beyer F, Broadbridge A, Dobson K, Landes D, Moffat S, Watt RG, Sniehotta FF, Freeman R, Paisi M, Bambra C, Craig D, Kaner E, Ramsay SE. Investigating the Effectiveness and Acceptability of Oral Health and Related Health Behaviour Interventions in Adults with Severe and Multiple Disadvantage: Protocol for a Mixed-Methods Systematic Review. International Journal of Environmental Research and Public Health 2021, 18(21), 11554.
  • Hall A, Boulton E, Kunonga P, Spiers G, Beyer F, Bower P, Craig D, Todd C, Hanratty B. Identifying older adults with frailty approaching end-of-life: A systematic review. Palliative Medicine 2021, Epub ahead of print.
  • Faraday J, Abley C, Beyer F, Exley C, Moynihan P, Patterson JM. How do we provide good mealtime care for people with dementia living in care homes? A systematic review of carer–resident interactions. Dementia 2021, 20(8), 3006-3031.
  • Joyes EC, McGowan LJ, Adams EA, Paisi M, Burrows M, Shabaninejad H, Beyer F, Haddow K, Coyte A, Landes D, Moffatt S, Watt RG, Sniehotta FF, Bambra C, Craig D, Kaner E, Ramsay SE. Exploring interventions to improve the oral health and related health behaviours of adults experiencing severe and multiple disadvantage: protocol for a qualitative study with stakeholders. International Journal of Environmental Research and Public Health 2021, 18(22), 11755.
  • McGowan VJ, Buckner S, Mead R, McGill E, Ronzi S, Beyer F, Bambra C. Examining the effectiveness of place-based interventions to improve public health and reduce health inequalities: an umbrella review. BMC Public Health 2021, 21, 1888.
  • Kunonga TP, Spiers GF, Beyer FR, Hanratty B, Boulton E, Hall A, Bower P, Todd C, Craig D. Effects of Digital Technologies on Older People's Access to Health and Social Care: Umbrella Review. Journal of Medical Internet Research 2021, 23(11), e25887.
  • McGowan L, Joyes E, Adams E, Richmond C, Shabaninejad H, Beyer F, Broadbridge A, Dobson K, Landes D, Moffat S, Watt R, Sniehotta F, Paisi M, Bambra C, Craig D, Kaner E, Ramsay S. Systematic review of oral health and related health behaviour interventions in adults with severe and multiple disadvantages. PROSPERO 2020, CRD42020202416.
  • Bray N, Kolehmainen N, McAnuff J, Tanner L, Tuersley L, Beyer F, Grayston A, Wilson D, Edwards RT, Noyes J, Craig D. Powered mobility interventions for very young children with mobility limitations to aid participation and positive development: the EMPoWER evidence synthesis. Health Technology Assessment 2020, 24(50), 1-194.
  • Sowden S, Nezafat Maldonado B, Wildman J, Cookson R, Thomson R, Lambert M, Beyer F, Bambra C. Interventions to reduce inequalities in avoidable hospital admissions: explanatory framework and systematic review protocol. BMJ Open 2020, 10, e035429.
  • McSweeney L, Breckons M, Fattakhova G, Oluboyede Y, Vale L, Ternent L, Balp MM, Doward L, Brass CA, Beyer F, Sanyal A, Anstee QM. Health-Related Quality of Life and Patient-Reported Outcome Measures in NASH-related Cirrhosis. JHEP Reports 2020, 2(3), 100099.
  • Dawson S, Kunonga P, Beyer F, Spiers G, Booker M, McDonald R, Cameron A, Craig D, Hanratty B, Salisbury C, Huntley A. Does health and social care provision for the community dwelling older population help to reduce unplanned secondary care, support timely discharge and improve patient well-being? A mixed-method meta review of systematic reviews. F1000Research 2020, 9, 857.
  • Jones WS, Rice S, Power HM, Maniatopoulos G, Suklan J, Beyer F, Wilcox MH, Permain M, Simpson AJ, Price DA, Allen AJ. Cost consequences for the NHS of using a two-step testing method for the detection of Clostridium difficile with a point of care, polymerase chain reaction test as the first step. Diagnostics 2020, 10(10), 819.
  • Potthoff S, Rasul O, Sniehotta FF, Marques M, Beyer F, Thomson R, Avery L, Presseau J. The relationship between habit and healthcare professional behaviour in clinical practice: a systematic review and meta-analysis. Health Psychology Review 2019, 13(1), 73-90.
  • Beyer FR, Campbell F, Bertholet N, Daeppen JB, Saunders JB, Pienaar ED, Muirhead CR, Kaner EFS. The Cochrane 2018 Review on Brief Interventions in Primary Care for Hazardous and Harmful Alcohol Consumption: A Distillation for Clinicians and Policy Makers. Alcohol and Alcoholism 2019, 54(4), 417-427.
  • Schulte B, Kaner EFS, Beyer F, Schmidt CS, O'Donnell A. Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations. BMJ Open 2019, 9(10), e031503.
  • Wheatley A, Bamford C, Shaw C, Flynn E, Smith A, Beyer F, Fox C, Barber R, Parry SW, Howel D, Homer TM, Robinson AL, Allan L. Developing an Intervention for Fall-Related Injuries in Dementia (DIFRID): an integrated, mixed-methods approach. BMC Geriatrics 2019, 19, 57.
  • Allan LM, Wheatley A, Smith A, Flynn E, Homer T, Robalino S, Beyer FR, Fox C, Howel D, Barber R, Connolly JA, Robinson L, Parry SW, Rochester L, Corner L, Bamford C. An intervention to improve outcomes of falls in dementia: the DIFRID mixed-methods feasibility study. Health Technology Assessment 2019, 23(59), 1-208.
  • Garnett C, Crane D, Brown J, Kaner E, Beyer F, Muirhead C, Hickman M, Redmore J, de Vocht F, Beard E, Michie S. Reported Theory Use by Digital Interventions for Hazardous and Harmful Alcohol Consumption, and Association With Effectiveness: Meta-Regression. Journal of Medical Internet Research 2018, 20(2), e29.
  • Russell S, Ogunbayo OJ, Newham JJ, Heslop-Marshall K, Netts P, Hanratty B, Beyer F, Kaner E. Qualitative systematic review of barriers and facilitators to self-management of chronic obstructive pulmonary disease: views of patients and healthcare professionals. npj Primary Care Respiratory Medicine 2018, 28, 2.
  • Scott S, Beyer F, Parkinson K, Muir C, Graye A, Kaner E, Stead M, Power C, Fitzgerald N, Bradley J, Wrieden W, Adamson AJ. Non-Pharmacological Interventions to Reduce Unhealthy Eating and Risky Drinking in Young Adults Aged 18-25 Years: A Systematic Review and Meta-Analysis. Nutrients 2018, 10(10), 1538.
  • Scott S, Beyer F, Parkinson K, Muir C, Graye A, Kaner E, Stead M, Power C, Fitzgerald N, Bradley J, Wrieden W, Adamson A. Non-pharmacological interventions designed to reduce health risks due to unhealthy eating behaviour and linked risky or excessive drinking in adults aged 18-25 years: a systematic review and meta-analysis. Nutrients 2018, 10(10), 1538.
  • Beyer F, Lynch E, Kaner E. Brief Interventions in Primary Care: an Evidence Overview of Practitioner and Digital Intervention Programmes. Current Addiction Reports 2018, 5(2), 265–273.
  • Garnett CV, Crane D, Bown J, Kaner EFS, Beyer FR, Muirhead CR, Hickman M, Beard E, Redmore J, de Vocht F, Michie S. Behavior Change Techniques Used in Digital Behavior Change Interventions to Reduce Excessive Alcohol Consumption: A Meta-regression. Annals of Behavioral Medicine 2018, 52(6), 530-543.
  • Kaner EFS, Beyer FR, Garnett C, Crane D, Brown J, Muirhead C, Redmore J, O'Donnell A, Newham JJ, de Vocht F, Hickman M, Brown H, Maniatopoulos G, Michie S. Personalised digital interventions for reducing hazardous and harmful alcohol consumption in community-dwelling populations. Cochrane Database of Systematic Reviews 2017, (9), CD011479.
  • McParlin C, O'Donnell A, Robson SC, Beyer F, Moloney E, Bryant A, Bradley J, Muirhead CR, Nelson-Piercy C, Newbury-Birch D, Norman J, Shaw C, Simpson E, Swallow B, Yates L, Vale L. Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review. Journal of the American Medical Association 2016, 316(13), 1392-1401.
  • Bayliss HR, Beyer FR. Information retrieval for ecological syntheses. Research Synthesis Methods 2015, 6(2), 136-148.
  • Clarke M, Hogan V, Buck D, Shen J, Powell C, Speed C, Tiffin P, Sloper J, Taylor R, Nassar M, Joyce K, Beyer F, Thomson R, Vale L, McColl E, Steen N. An external pilot study to test the feasibility of a randomised controlled trial comparing eye muscle surgery against active monitoring for childhood intermittent exotropia [X(T)]. Health Technology Assessment 2015, 19(39).
  • Joyce KE, Beyer F, Thomson RG, Clarke MP. A systematic review of the effectiveness of treatments in altering the natural history of intermittent exotropia. British Journal of Ophthalmology 2015, 99(4), 440-450.
  • Beyer F, Wright K. Can we prioritise which databases to search? A case study using a systematic review of frozen shoulder management. Health Information & Libraries Journal 2013, 30(1), 49-58.
  • Robinson L, Dickinson C, Rousseau N, Beyer F, Clark A, Hughes J, Howel D, Exley C. A systematic review of the effectiveness of advance care planning interventions for people with cognitive impairment and dementia. Age and Ageing 2012, 41(2), 263-269.
  • Dickinson HO, Campbell F, Beyer FR, Nicolson DJ, Cook JV, Ford GA, Mason JM. Relaxation therapies for the management of primary hypertension in adults: a Cochrane review. Journal of Human Hypertension 2008, 22(12), 809-820.
  • Dickinson HO, Nicolson DJ, Campbell F, Cook JV, Beyer FR, Ford GA, Mason J. Magnesium supplementation for the management of essential hypertension in adults. Cochrane Database of Systematic Reviews 2006, 3, CD004640.
  • Ker K, Roberts I, Collier T, Beyer F, Bunn F, Frost C. Post-licence driver education for the prevention of road traffic crashes: A systematic review of randomised controlled trials. Accident Analysis and Prevention 2005, 37(2), 305-313.
  • Hrisos S, Eccles MP, Francis J, Kaner EFS, Johnston M, Beyer F, Dickinson H. How well do self-reported intentions predict clinicians' behaviour? A Systematic Review. Family Practice 2005, 22(1), 126-127.

• Conference Proceedings (inc. Abstracts)

  • Marshall C, Still M, Hassenfuss J, Stoniute A, Crooks J, Craig D, Sniehotta F, Exley C, Fisher A, Beyer F. Barriers, facilitators and interventions concerning organ donation in people from minority ethnic backgrounds: updating the evidence base. In: British Transplant Society Congress 2020 “Collaboration in Transplantation”. 2020, Belfast.
  • Marshall C, Still M, Hassenfuss J, Stoniute A, Crooks J, Craig D, Sniehotta F, Exley C, Fisher A, Beyer F. Barriers and facilitators to organ donation in people from minority ethnic backgrounds: a logic model. In: British Transplant Society Congress 2020 “Collaboration in Transplantation”. 2020, Belfast.
  • Potthoff S, Rasul O, Sniehotta F, Beyer F, Bryant A, Marques M, Thomson R, Avery L, Presseau J. A Systematic Review assessing the relationship between habit and healthcare professional behavior in clinical practice. In: International Journal of Behavioral Medicine. 2016, Melbourne, Australia: Springer.
  • McParlin C, O'Donnell A, Robson S, Beyer F, Moloney E, Bryant A, Bradley J, Muirhead C, Nelson-Peircey C, Newbury-Birch D, Norman J, Simpson E, Swallow B, Yates L, Vale L. A systematic review of the clinical-effectiveness of interventions for nausea and vomiting in pregnancy. In: British Maternal & Fetal Medicine Society (BMFMS) 17th Annual Conference 2015. 2015, London, UK: Wiley-Blackwell Publishing Ltd.

• Reports

  • Law J, Charlton J, McKean C, Beyer F, Fernandez-Garcia C, Mashayekhi A, Rush R. Final report Parent-child reading to improve language development and school readiness: A systematic review and meta-analysis. Newcastle University and Queen Margaret University, 2020.
  • Marshall C, Still M, Hasenfuss J, Stoniute A, Crooks J, Craig D, Sniehotta FF, Exley C, Fisher A, Beyer FR. Identifying interventions to increase organ donation rates in people from minority ethnic backgrounds. NIHR, 2019.
  • Law J, Charlton J, McKean C, Beyer F, Fernandez-Garcia C, Mashayekhi A, Rush R. Parent-child reading to improve language development and school readiness: A systematic review and meta-analysis. Newcastle upon Tyne: Nuffield Foundation, 2018.
  • Burford B, Rothwell C, Beyer F, Tanner L, Vance G. Best Practice in the Assessment of Competence: A Literature Review. London: General Medical Council, 2018.
  • O'Donnell A, McParlin C, Robson SC, Beyer F, Moloney E, Bryant A, Bradley J, Muirhead C, Nelson-Piercy C, Newbury-Birch D, Norman J, Simpson E, Swallow B, Yates L, Vale L. Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: a systematic review and economic assessment. London: NIHR Journals Library, 2016. Health Technology Assessment.
  • Clarke M, Powell C, Buck D, McColl E, Speed C, Hogan V, Vale L, Shen J, Steen N, Nassar M, Thomson R, Joyce K, Beyer F, Taylor R, Tiffin P, Sloper J. An External Pilot Study to Test the Feasibility of a Randomised Controlled Trial comparing Eye Muscle Surgery against Active Monitoring for Childhood Intermittent Distance Exotropia [X(T)]. Pilot Rehearsal Trial and Feasibility Study, Final Report to the NIHR HTA, HTA Project 09/01/20, July 2013. 2014. In Press.
  • Newbury-Birch D, Gilvarry E, McArdle P, Ramesh V, Stewart S, Walker J, Avery L, Beyer F, Brown N, Jackson K, Lock C, McGovern R, Kaner E. Impact of alcohol consumption on young people: A systematic review of published reviews. Department for Children, Schools and Families, 2009. DCSF-RR067.
  • Dickinson HO, Lock CA, Lecouturier J, Beyer F, Mason J. A systematic review of calcium and vitamin D for the prevention of osteoporotic fractures. London, UK: submitted to Royal College of Nurses, 2005.

• Reviews

  • Hogg HDJ, Al-Zubaidy M, Talks J, Denniston AK, Kelly CJ, Malawana J, Papoutsi C, Teare MD, Keane PA, Beyer FR, Maniatopoulos G. Stakeholder Perspectives of Clinical Artificial Intelligence Implementation: Systematic Review of Qualitative Evidence. Journal of Medical Internet Research 2023, 25, e39742.
  • Beyer FR, Kenny RPW, Johnson E, Caldwell DM, Garnett C, Rice S, Simpson J, Angus C, Craig D, Hickman M, Michie S, Kaner EFS. Practitioner and digitally delivered interventions for reducing hazardous and harmful alcohol consumption in people not seeking alcohol treatment: a systematic review and network meta-analysis. Addiction 2022, epub ahead of print.
  • Stephen SE, Murphy JM, Beyer FR, Sellstrom D, Paleri V, Patterson JM. Early postoperative functional outcomes following transoral surgery for oropharyngeal cancer: A systematic review. Head and Neck 2022, 44(2), 530-547.
  • Spiers GF, Kunonga TP, Beyer F, Craig D, Hanratty B, Jagger C. Trends in health expectancies: A systematic review of international evidence. BMJ Open 2021, 11(5), e045567.
  • Grimani A, Goffe L, Tang MY, Beyer F, Sniehotta FF, Vlaev I. Effectiveness of personal letters to healthcare professionals in changing professional behaviours: a systematic review protocol. Systematic Reviews 2021, 10, 94.
  • Robalino S, Nyakang'o SB, Beyer FR, Fox C, Allan LM. Effectiveness of interventions aimed at improving physical and psychological outcomes of fall-related injuries in people with dementia: a narrative systematic review. Systematic Reviews 2018, 7, 31.
  • Parmelli E, Flodgren G, Beyer F, Baillie N, Schaafsma ME, Eccles MP. The effectiveness of strategies to change organisational culture to improve healthcare performance: a systematic review. Implementation Science 2011, 6(1), 33.
  • Flodgren G, Eccles MP, Shepperd S, Scott A, Parmelli E, Beyer FR. An overview of reviews evaluating the effectiveness of financial incentives in changing healthcare professional behaviours and patient outcomes. Cochrane Database of Systematic Reviews 2011, 2011(7), CD009255.
  • Flodgren G, Deane K, Dickinson HO, Kirk S, Alberti H, Beyer FR, Brown JG, Penney TL, Summerbell CD, Eccles MP. Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction in overweight and obese people. Cochrane Database of Systematic Reviews 2010, 2010(3), CD000984.
  • Kaner EFS, Dickinson HO, Beyer F, Pienaar E, Schlesinger C, Campbell F, Saunders JB, Burnand B, Heather N. The effectiveness of brief alcohol interventions in primary care settings: A systematic review. Drug and Alcohol Review 2009, 28(3), 301-323.
  • Beyer F, Ker K. Street lighting for preventing road traffic injuries. Cochrane Database of Systematic Reviews 2009, (1), CD004728.
  • Hrisos S, Eccles MP, Francis JJ, Dickinson HO, Kaner EFS, Beyer F, Johnston M. Are there valid proxy measures of clinical behaviour? a systematic review. Implementation Science 2009, 4(1), 37.
  • Dickinson HO, Nicolson DJ, Campbell F, Beyer FR, Mason J. Potassium supplementation for the management of primary hypertension in adults. Cochrane Database of Systematic Reviews 2006, (3), CD004641.
  • Campbell F, Dickinson HO, Cook JVF, Beyer FR, Eccles M, Mason JM. Methods underpinning national clinical guidelines for hypertension: Describing the evidence shortfall. BMC Health Services Research 2006, 6, 47.
  • Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV, Williams B, Ford GA. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. Journal of Hypertension 2006, 24(2), 215-233.
  • Eccles MP, Hrisos S, Francis J, Kaner EF, Dickinson HO, Beyer F, Johnston M. Do self- reported intentions predict clinicians' behaviour: A systematic review. Implementation Science 2006, 1(28), 10.
  • Beyer FR, Dickinson HO, Nicolson DJ, Ford GA, Mason J. Combined calcium, magnesium and potassium supplementation for the management of primary hypertension in adults. Cochrane Database of Systematic Reviews 2006, (3), CD004805.
  • Dickinson HO, Nicolson DJ, Cook JV, Campbell F, Beyer FR, Ford GA, Mason J. Calcium supplementation for the management of primary hypertension in adults. Cochrane Database of Systematic Reviews 2006, (2), CD004639.
  • Robinson L, Hutchings D, Corner L, Beyer F, Dickinson H, Vanoli A, Finch T, Hughes J, Ballard C, May C, Bond J. A systematic literature review of the effectiveness of non-pharmacological interventions to prevent wandering in dementia and evaluation of the ethical implications and acceptability of their use. Health Technology Assessment 2006, 10(26), 1-124.