Staff Profile
Dr Connor Richardson
Neuroepidemiology Research Associate
- Email: connor.richardson2@ncl.ac.uk
- Telephone: 0191 20 82105
- Personal Website: https://www.ncl.ac.uk/medical-sciences/research/institutes/population-health/
- Address: Population Health Sciences Institute
Faculty of Medical Sciences
Newcastle University
Newcastle Biomedical Research Building, 2.37
Campus for Ageing and Vitality
NE4 5PL
I am a member of the Population Health Sciences Institute (NUPHSI) and work across the Ageing and Geroscience and Innovation, Methodology and Application themes. My research also covers several Newcastle University Centres of Research Excellence (NUCoRE):
- Centre for Ageing and Inequality
- Centre for Data
- Centre for Healthier Lives
Introduction
A biomedical scientist by training, I began my career in cancer pharmacology researching Poly (ADP-ribose) Polymerase (PARP) inhibitors and bio-imaging of dermal immunology. My postgraduate work has focused on epidemiology, advanced statistics and Machine Learning/Artificial Intelligence in the fields of ageing, dementia and neuropathology.
In my current role I am a Research Associate in the Population Health Sciences Institute (NUPHSI) as well as the research statistician for the Cognitive Function and Ageing Studies (CFAS) group, a multicentre population cohort study based at the University of Cambridge. My primary research interests are applying state of the art statistical methodology including, machine learning/ Artificial Intelligence, to understanding neuropathological risk in older people of cognitive impairment and dementia.
As well as research I enjoy an active role in the wider university including student supervision and teaching. I am also a representative of NUPHSI on the FMS Post-doctoral researchers committee and the NUPHSI Equality, Diversity and Inclusion (EDI) committee.
In 2020 I have also worked alongside colleagues with North East NHS trusts, providing epidemiological modelling for the COVID-19 response.
Research Gate ORCID Scopus Twitter
Roles and Responsibilities
- PHSI Equality, Diversity & Inclusion Deputy Lead
- Research Associate, Population Health Sciences Institute
- Statistician, Cognitive Function and Ageing Studies (CFAS)
- Teaching & Supervision
- Faculty of Medical Sciences post-doc society committee member, Newcastle University
Qualifications
- BSc - Biomedical Sciences - Newcastle University (2013)
- MSc - Public Health and Health Service Research - Newcastle University (2015)
- PhD - Mild Cognitive Impairment (MCI) in the Population: New Criteria and Cohort Effects (2019)
Applied Epidemiology
- Neurodegenerative diseases and ageing
- Population prevalence, incidence and risk factors for neurodegenerative diseases
- Role of biomarkers in predicting risk of neurodegeneration
- Neuropathology of neurodegenerative disease in the population
- Pathways of progression from mild cognitive impairment to severe neurodegenerative disease.
Quantitative Methodology
- Analysis of complex cognitive outcomes
- Missing data models for epidemiological investigations
- Longitudinal models of epidemiological data
- Incorporating biomedical and neuropathological data into population based risk modelling
- Machine learning and Artificial Intelligence
Lecturing
- MSc Public health and health services research: Chronic Disease Epidemiology
- MSc Public health and health services research: Introduction to Quantitative Research Methods
- MPharm: Introduction to Statistics
- BSc Biomedical Sciences: Public Health & Ageing
Student Supervision
I have supervised a number of undergraduate and masters dissertation projects.
- Richardson CD, Roscoe H, Green E, Brooks R, Barnes L, Matthews FE, Brayne C. Impact of COVID-19 Policies on Perceptions of Loneliness in people aged 75 years and over in the Cognitive Function and Ageing Study (CFAS II). Journal of the American Geriatrics Society 2022, epub ahead of print.
- Stephan BCM, Tang E, Pakpahan E, Biswasd B, Guptae A, Fairley A, Bosco A, Richardson CD, Robinson L, Siervo M. Secular Trends in Dementia Free Cognitive Function in Older Adults: A Systematic Review. Journal of Alzheimer's Disease 2022, 88(2), 417-428.
- Ellmerich S, Taylor GW, Richardson CD, Minett T, Schmidt AF, Brayne C, Matthews FE, Ince PG, Wharton SB, Pepys MB. Dementia in the older population is associated with neocortex content of serum amyloid P component. Brain Communications 2021, 3(4), fcab225.
- Waller R, Narramore R, Simpson JE, Heath PR, Verma N, Tinsley M, Barnes J, Haris H, Henderson FE, Matthews FE, Richardson CD, Brayne C, Ince PG, Kalaria R, Wharton SB. Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer's and small vessel disease pathologies. Brain Pathology 2021, 31(3), e12928.
- McGrattan AM, Zhu Y, Richardson CD, Mohan D, Soh YC, Sajjad A, Aller CV, Chen S, Paddick SM, Prina M, Siervo M, Robinson LA, Stephan BCM. Prevalence and Risk of Mild Cognitive Impairment in Low and Middle-Income Countries: A Systematic Review. Journal of Alzheimer's Disease 2021, 79(2), 743-762.
- Chambers A, Bury JJ, Minett T, Richardson CD, Brayne C, Ince PG, Shaw PJ, Garwood CJ, Heath PR, Simpson JE, Matthews FE, Wharton SB, CFAS. Advanced Glycation End Product Formation in Human Cerebral Cortex Increases with Alzheimer-type Neuropathologic Changes but is Not Independently Associated with Dementia in a Population-Derived Aging Brain Cohort. Journal of Neuropathology and Experimental Neurology 2020, 79(9), 950-958.
- Richardson C, Stephan BCM, Robinson L, Brayne C, Matthews FE. Two-decade change in prevalence of cognitive impairment in the UK. European Journal of Epidemiology 2019, 34, 1085-1092.
- Lavrencic LM, Richardson C, Harrison SL, Muniz-Terrera G, Keage HAD, Brittain K, Kirkwood TBL, Jagger C, Robinson L, Stephan BCM. Is There a Link between Cognitive Reserve and Cognitive Function in the Oldest-Old?. Journals of Gerontology: Series A 2018, 73(4), 499-505.
- Matthews F, Richardson CD. NIH Collaboration Report: Relationships between Education, Deprivation and Incident Dementia. 2018.
- Richardson C, Stephan BCM, Robinson L, Matthews F, The Cognitive Function and Ageing Study. Risk of Two-Year Progression from Mild Cognitive Impairment to Dementia: Results from the Cognitive Function and Ageing Study. In: Alzheimer's Association International Conference (AAIC 2018). 2018, Chicago, Illinois: Elsevier.
- Richardson C, Stephan B, Robinson L, Brayne C, Matthews F. The Changing Face of Mild Cognitive Impairment (MCI) and Mild Dementia. In: Alzheimer's Association International Conference 2017. 2017, London, UK: Alzheimer's & Dementia: The Journal of the Alzheimer's Association.
- Richardson C, Harrison S, Brittain K, Muniz-Terrera G, Robinson L, Stephan B. Associations between cognitive reserve and cognitive function in the very old: Newcastle 85+ Study. In: 2016 GSA Annual Scientific Meeting. 2016, New Orleans, Louisiana: Oxford University Press.
- Wang XN, McGovern N, Gunawan M, Richardson C, Windebank M, Siah TW, Lim HW, Fink K, Li J, Ng LG, Ginhoux F, Angeli V, Collin M, Haniffa M. A Three Dimensional Atlas of Human Dermal Leukocytes, Lymphatics and Blood Vessels. Journal of Investigative Dermatology 2014, 134, 965-974.
- Wang XN, McGovern N, Gunawan M, Richardson C, Windebank M, Siah TW, Lim HY, Fink K, Li JY, Ng L, Ginhoux F, Angeli V, Collin M, Haniffa M. Microanatomical dissection of the human dermis: the three-dimensional relationship between leucocytes, lymphatics and blood vessels. In: British Society of Investigative Dermatology Annual Meeting. 2014, Newcastle upon Tyne: Wiley-Blackwell.