Staff Profile

Background

PhD student and Associate Researcher within the Stroke Research Group at Newcastle University. Graduated with a BSc(Hons) in Psychology from Northumbria University in 2016 and an MSc in Cognitive Neuroscience from Durham University in 2018.

Worked on PEARS (Promoting Effective and Rapid Stroke Care) programme from 2018-2019 and SINONIMS (Study In NOvel Neuromuscular Imaging biomarkers for Motor outcome in Stroke) study from 2019-2022. 

Qualifications

BSc (Hons) Psychology

First-Class Honours

Northumbria University

July 2016

MSc Cognitive Neuroscience

Distinction

Durham University

January 2018

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Research Interests

Biomarkers in stroke, Stroke Diagnosis, Acute stroke care, Stroke treatments, Stroke recovery, Stroke Rehabilitation, Translational Neuroscience,  Clinical Neuroscience, Applied Neuroscience, Basic Neuroscience; Cognitive Neuroscience.  

Research Projects

Promoting Effective and Rapid Stroke Care (PEARS)

We aimed to increase the efficiency of acute stroke care by implementing and exploring various methods to optimise pre-hospital protocols and access to treatment to improve functional outcomes for patients.

Objective 1

Paramedic Acute Stroke Treatment Assessment (PASTA)

I conducted a survey to assess the views of paramedics involved in the PASTA trial which explored the impact of an enhanced paramedic role on patient treatment and outcomes. 

Objective 2

PEARS 2

The aim of PEARS 2 was to increase thrombectomy provision to eligible patients by optimising the configuration of stroke services.

I constructed a survey for the helicopter emergency services to assess the feasibility of the use of air-ambulances for secondary transfer of stroke patients to neuroscience centres for thrombectomy. I presented the results of the survey at UK Stroke Forum Conference. I also conducted a survey on patient and public preferences in relation to thrombectomy service configuration. 

Pre-hospital Diagnostics Literature Review 

We conducted a scoping review of technologies, with potential for pre-hospital stroke (and sub-type) diagnosis and/or stratification, which could be used by paramedics. 

Study in Novel Neuro-muscular Imaging Biomarkers for Motor Outcome in Stroke (SINONIMS)

I am currently working on the SINONIMS study which aims to utilise neuro-muscular imaging biomarkers to predict lower limb motor outcome following stroke. Advanced Magnetic Resonance Imaging (MRI) will be used to assess white matter integrity in the brain, as well as muscle quality in the lower limb. The study will examine the impact of sarcopaenia (age related muscle degeneration), myopaenia (disease related muscle degeneration) and loss of connectivity in the corticospinal tract on motor recovery. The goal is to  increase the accuracy of prognosis to allow provision of tailored treatments.  

PhD using artificial intelligence and blood biomarkers to improve stroke treatment

My PhD will firstly involve retrospective machine learning analysis of an existing stroke patient dataset, with the aim of finding an algorithm to discern stroke from stroke mimic patients. We are also conducting a prospective clinical study examining the combined and individual utility of using blood biomarkers D-Dimer and purines to diagnose stroke and its subtypes. The literature review will explore clinical factors indicative of prognosis after thrombectomy, a surgery for a subtype of stroke involving occlusion of a large artery.

Formal Teaching Experience

Tutored undergraduate students..

Taught Biomedical Sciences Seminar on Stroke diagnostic blood biomarkers.

Informal Teaching Experience

Significant time spent personally tutoring friends and course mates during undergraduate and postgraduate study:

-Assistance with statistical methods.

-Providing accessible explanations to assist conceptualisation of complex concepts.

-Writing/editing guidance. 

• Articles

  • Lumley H, Shaw L, Morris J, Alton A, White P, Ford G, James M, Price C. Associations between basic physiological observations recorded pre-thrombectomy and functional outcome: a systematic review and meta-analysis. Frontiers in Stroke 2023, 2, 1283312.
  • Elameer M, Lumley H, Moore SA, Marshall K, Alton A, Smith FE, Gani A, Blamire A, Rodgers H, Price CIM, Mitra D. A prospective study of MRI biomarkers in the brain and lower limb muscles for prediction of lower limb motor recovery following stroke. Frontiers in Neurology 2023, 14, 1229681.
  • Sutcliffe L, Lumley H, Shaw L, Francis R, Price CI. Surface Electroencephalography (EEG) During the Acute Phase of Stroke to Assist With Diagnosis and Prediction of Prognosis: a Scoping Review. BMC Emergency Medicine 2022, 22, 29.
  • Coughlan D, McMeekin P, Flynn D, Ford GA, Lumley H, Burgess D, Balami J, Mawson A, Craig D, Rice S, White P. Secondary transfer of emergency stroke patients eligible for mechanical thrombectomy by air in rural England: economic evaluation and considerations. Emergency Medicine Journal 2021, 38(1), 33-39.
  • Balami JS, Coughlan D, White PM, McMeekin P, Flynn D, Roffe C, Natarajan I, Chembala J, Nayak S, Wiggam I, Flynn P, Simister R, Sammaraiee Y, Sims D, Nader K, Dixit A, Craig D, Lumley H, Rice S, Burgess D, Foddy L, Hopkins E, Hudson B, Jones R, James MA, Buchan AM, Ford GA, Gray AM. The cost of providing mechanical thrombectomy in the UK NHS: a micro-costing study. Clinical Medicine Journal 2020, 20(3), e40-e45.
  • Lumley HA, Flynn D, Shaw L, McClelland G, Ford GA, White P, Price C. A Scoping Review of Pre-hospital Technology to Assist Ambulance Personnel with Patient Diagnosis or Stratification during the Emergency Assessment of Suspected Stroke. BMC Emergency Medicine 2020, 20, 30.
  • McMeekin P, Flynn D, Allen M, Coughlan D, Ford GA, Lumley H, Balami JS, James MA, Stein K, Burgess D, White P. Estimating the Effectiveness and Cost-Effectiveness of Establishing Additional Endovascular Thrombectomy Stroke Centres in England: A Discrete Event Simulation. BMC Health Services Research 2019, 19, 821.

• Conference Proceedings (inc. Abstracts)

  • Shaw L, Lendrem C, Lumley H, Morris J, White P, Price C. Stroke Biomarker Evaluation for Large Vessel Occlusion (StroBE-LVO): Work in Progress. In: UK Stroke Forum. 2024, Birmingham: International Journal of Stroke. In Preparation.
  • Lumley H, Shaw L, Lendrem C, McClelland G, McMeekin P, Price C. Development and Accuracy of a Machine Learning Algorithm to Predict Stroke Mimic Conditions during Prehospital Assessment. In: 19th UK Stroke Forum Conference. 2024, Liverpool: Sage Publications Ltd.
  • Lumley HA, Shaw L, Morris J, Alton A, White P, Ford GA, James M, Price C. Associations between basic physiological observations recorded pre-thrombectomy and functional outcome: a systematic review and meta-analysis. In: UK Stroke Forum. 2024, Birmingham: International Journal of Stroke. In Preparation.
  • Shaw L, Lumley H, Lendrem C, White P, Price C. Whole Blood Purine And D-Dimer Measurement For Identification Of Large Vessel Occlusion Stroke: A Prospective Observational Study. In: UK Stroke Forum 2024. 2024, Liverpool: International Journal of Stroke. In Preparation.
  • Lumley H, Elameer M, Price CI, Moore SA, Gani A, Smith F, English P, Rodgers H, Blamire A, Mitra D. Study in Novel Neuro-muscular Imaging Biomarkers for Motor Outcome in Stroke (SINONIMS). In: Communications to the International Sarcopenia Translational Research Conference 2021. Journal of Frailty, Sarcopenia and Falls. 2021, Virtual: Hylonome Publications.
  • Lumley H, Flynn D, Coughlan D, McMeekin P, Ford GA, Craig D, Rice S, Burgess D, Balami J, Mawson A, White P. Secondary transfers by helicopter emergency services for thrombectomy in rural England: a feasibility study (updated). In: UK Stroke Forum. 2019, Telford: Sage Publications Ltd.
  • Lumley H, Flynn D, Coughlan D, McMeekin P, Ford GA, Craig D, Rice S, Burgess D, Balami JS, Mawson A, White PM. Secondary Transfers by Helicopter Emergency Services for Thrombectomy in Rural England: a Feasibility Study. In: UK Stroke Forum 2018. 2018, Telford, UK: Sage Publications Ltd.
  • Flynn D, Coughlan D, McMeekin P, Ford GA, Craig D, Rice S, Burgess D, Balami J, Mawson A, Lumley H, White P. Secondary Transfer of Stroke Patients for Thrombectomy by Air Ambulance in England: A Cost-Effectiveness Analysis. In: European Stroke Organisation Conference. 2018, Gothenburg, Sweden: Sage Publications Ltd.
  • Balami JS, Coughlan D, McMeekin P, White PM, Flynn D, Roffe C, Wiggam I, Flynn P, Chembala J, Natarajan I, Dixit A, Hunter A, Foddy L, Hopkins E, Lumley H, Rice S, Burgess D, Craig D, Buchan AM, Ford GA, Gray A. Case Costing of Mechanical Thrombectomy for Acute Ischaemic Stroke in Routine Clinical Setting: Cost Differences Between Mothership vs Drip and Ship. In: UK Stroke Forum 2018. 2018, Telford, United Kingdom: International Journal of Stroke.

• Review

  • Lumley H, Flynn D, Ford GA, Inskip A, McClelland G, Shaw L, White PM, Price CIM. A Review of Technology to Assist with Patient Stratification during the Emergency Assessment of Suspected Stroke. PROSPERO 2018 2018, CRD42018087611.