Staff Profile
Professor William Willats
Prof of Molecular Agri-Diagnostics
Background
For a full list of my publications please see my Google Scholar Profile
Publications
- Cuesta-Seijo JA, Nielsen MM, Ruzanski C, Krucewicz K, Beeren SR, Rydhal MG, Yoshimura Y, Striebeck A, Motawia MS, Willats WGT, Palcic MM. In vitro Biochemical Characterization of All Barley Endosperm Starch Synthases. Frontiers in Plant Science 2016, 6, 1265.
- Andersen MCF, Boos I, Marcus SE, Kračun SK, Rydahl MG, Willats WGT, Knox JP, Clausen MH. Characterization of the LM5 pectic galactan epitope with synthetic analogues of β-1,4-d-galactotetraose. Carbohydrate Research 2016, 436, 36-40.
- Vendittoa I, Luis AS, Rydahl M, Schückel J, Fernandes VO, Vidal-Melgosa S, Bule P, Goyal A, Pires VMR, Dourado CG, Ferreira LMA, Coutinho PM, Henrissat B, Knox JP, Baslé A, Najmudin S, Gilbert HJ, Willats WGT, Fontes CMGA. Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition. Proceedings of the National Academy of Sciences of the United States of America 2016, 113(26), 7136-7141.
- Andersen MCF, Kracun SK, Rydahl MG, Willats WGT, Clausen MH. Synthesis of β-1,4-Linked Galactan Side-Chains of Rhamnogalacturonan I. Chemistry: A European Journal 2016, 22(33), 11543-11548.
- Kračun SK, Schückel J, Westereng B, Thygesen LG, Monrad RN, Eijsink VG, Willats WGT. A new generation of versatile chromogenic substrates for high-throughput analysis of biomass-degrading enzymes. Biotechnology for Biofuels 2015, 8, 70.
- Vidal-Melgosa S, Pedersen HL, Schückel J, Arnal G, Dumon C, Amby DB, Monrad RN, Westereng B, Willats WG. A new versatile microarray-based method for high throughput screening of carbohydrate-active enzymes. The Journal of Biological Chemistry 2015, 290(14), 9020-9036.
- Hernandez-Gomez MC, Rydahl MG, Rogowski A, Morland C, Cartmell A, Crouch L, Labourel A, Fontes CMGA, Willats WGT, Gilbert HJ, Knox JP. Recognition of xyloglucan by the crystalline cellulose-binding site of a family 3a carbohydrate-binding module. FEBS Letters 2015, 589(18), 2297-2303.
- Umu ÖC, Frank JA, Fangel JU, Oostindjer M, daSilva CS, Bolhuis EJ, Bosch G, Willats WG, Pope PB, Diep DB. Resistant starch diet induces change in the swine microbiome and a predominance of beneficial bacterial populations. Microbiome 2015, 3(1), 16.
- Rossez Y, Holmes A, Lodberg-Pedersen H, Birse L, Marshall J, Willats WGT, Toth IK, Holden NJ. Escherichia coli Common Pilus (ECP) Targets Arabinosyl Residues in Plant Cell Walls to Mediate Adhesion to Fresh Produce Plants. The Journal of Biological Chemistry 2014, 289(49), 34349-34365.
- Agger JW, Isaksen T, Várnai A, Vidal-Melgosa S, Willats WG, Ludwig R, Horn SJ, Eijsink VG, Westereng B. Discovery of LPMO activity on hemicelluloses shows the importance of oxidative processes in plant cell wall degradation. Proceedings of the National Academy of Sciences of the United States of America 2014, 111(17), 6287-6292.
- Marriott PE, Sibout R, Lapierre C, Fangel JU, Willats WG, Hofte H, Gómez LD, McQueen-Mason S. Range of cell-wall alterations enhance saccharification in Brachypodium distachyon mutants. Proceedings of the National Academy of Sciences of the United States of America 2014, 111(40), 14601-14606.
- Malinovsky FG, Fangel JU, Willats WG. The role of the cell wall in plant immunity. Frontiers in Plant Science 2014, 5, 178.
- Mravec J, Kracun SK, Rydahl MG, Westereng B, Miart F, Clausen MH, Fangel JU, Daugaard M, Van Cutsem P, De Fine Licht HH, Höfte H, Malinovsky FG, Domozych DS, Willats WG. Tracking developmentally regulated post-synthetic processing of homogalacturonan and chitin using reciprocal oligosaccharide probes. Development 2014, 141(24), 4841-4850.
- Sørensen I, Rose JKC, Doyle JJ, Domozych DS, Willats WG. The charophycean green algae provide insights into the early origins of plant cell walls. Plant signaling & behavior 2012, 7(1), 1-3.
- Pedersen HL, Fangel JU, McCleary B, Ruzanski C, Rydahl MG, Ralet MC, Farkas V, von Schantz L, Marcus SE, Andersen MC, Field R, Ohlin M, Knox JP, Clausen MH, Willats WGT. Versatile High Resolution Oligosaccharide Microarrays for Plant Glycobiology and Cell Wall Research. The Journal of Biological Chemistry 2012, 287(47), 39429-39438.
- Marcus SE, Blake AW, Benians TAS, Lee KJD, Poyser C, Donaldson L, Leroux O, Rogowski A, Petersen HL, Boraston A, Gilbert HJ, Willats WGT, Knox JP. Restricted access of proteins to mannan polysaccharides in intact plant cell walls. Plant Journal 2010, 64(2), 191-203.
- Smallwood M, Yates EA, Willats WGT, Martin H, Knox JP. Immunochemical comparison of membrane-associated and secreted arabinogalactan-proteins in rice and carrot. Planta 198(3):452-459 1996, 198(3), 452-459.
- Venditto I, Luis AS, Rydahl MG, Schuckel J, Fernandes VO, Melgosa SV, Bule P, Goyal A, Pires VMR, Dourado CG, Ferreira LMA, Coutinho PM, Henrissat B, Knox JP, Basle A, Najmudin S, Gilbert HJ, Willats WG, Fontes CMGA. The complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition. In: 2016 Annual Meeting of the Society for Glycobiology. 2016, New Orleans, Louisiana: Oxford University Press.
- Torode TA, O'Neill R, Marcus SE, Cornuault V, Pose S, Lauder RP, Kračun SK, Rydahl MG, Andersen MCF, Willats WGT, Braybrook SA, Townsend BJ, Clausen MH, Knox JP. Branched Pectic Galactan in Phloem-Sieve-Element Cell Walls: Implications for Cell Mechanics. Plant Physiology 2018, 176(2), 1547-1558.
- Salmean AA, Guillouzo A, Duffieux D, Jam M, Matard-Mann M, Larocque R, Pedersen HL, Michel G, Czjzek M, Willats WGT, Herve C. Double blind microarray-based polysaccharide profiling enables parallel identification of uncharacterized polysaccharides and carbohydrate-binding proteins with unknown specificities. Scientific Reports 2018, 8(1), 2500.
- Solden LM, Naas AE, Roux S, Daly RA, Collins WB, Nicora CD, Purvine SO, Hoyt DW, Schückel J, Jorgensen B, Willats W, Spalinger DE, Firkins JL, Lipton MS, Sullivan MB, Pope PB, Wrighton KC. Interspecies cross-feeding orchestrates carbon degradation in the rumen ecosystem. Nature Microbiology 2018, 3, 1274-1284.
- Sequeira S, Kavanaugh D, MacKenzie DA, Suligoj T, Walpole S, Leclaire C, Gunning AP, Latousakis D, Willats WGT, Angulo J, Dong C, Juge N. Structural basis for the role of serine-rich repeat proteins from Lactobacillus reuteri in gut microbe–host interactions. Proceedings of the National Academy of Sciences 2018, 115(12), E2706-E2715.
- Andersen MCF, Boos I, Kinnaert C, Awan SI, Pedersen HL, Kracun SK, Lanz G, Rydahl MG, Kjaerulff L, Hakansson M, Kimbung R, Logan DT, Gotfredsen CH, Willats WGT, Clausen MH. Synthesis of branched and linear 1,4-linked galactan oligosaccharides. Organic and Biomolecular Chemistry 2018, 16(7), 1157-1162.
- Fangel JU, Eiken J, Sierksma A, Schols HA, Willats WGT, Harholt J. Tracking polysaccharides through the brewing process. Carbohydrate Polymers 2018, 196, 465-473.
- Mravec J, Kracun SK, Rydahl MG, Westereng B, Pontiggia D, De Lorenzo G, Domozych DS, Willats WGT. An oligogalacturonide-derived molecular probe demonstrates the dynamics of calcium-mediated pectin complexation in cell walls of tip-growing structures. Plant Journal 2017, 91(3), 534-546.
- Mravec J, Kracun SK, Zemlyanskaya E, Rydahl MG, Guo X, Picmanova M, Sorensen KK, Ruzicka K, Willats WGT. Click chemistry-based tracking reveals putative cell wall-located auxin binding sites in expanding cells. Scientific Reports 2017, 7(1), 15988.
- Zietsman AJJ, Moore JP, Fangel JU, Willats WGT, Vivier MA. Combining hydrothermal pretreatment with enzymes de-pectinates and exposes the innermost xyloglucan-rich hemicellulose layers of wine grape pomace. Food Chemistry 2017, 232, 340-350.
- Rydahl MG, Kracun SK, Fangel JU, Michel G, Guillouzo A, Genicot S, Mravec J, Harholt J, Wilkens C, Motawia MS, Svensson B, Tranquet O, Ralet M-C, Jorgensen B, Domozych DS, Willats WGT. Development of novel monoclonal antibodies against starch and ulvan - Implications for antibody production against polysaccharides with limited immunogenicity. Scientific Reports 2017, 7, 9326.
- O'Neill EC, Kuhaudomlarp S, Rejzek M, Fangel JU, Alagesan K, Kolarich D, Willats WGT, Field RA. Exploring the Glycans of Euglena gracilis. Biology 2017, 6(4), 45.
- Salmean AA, Duffieux D, Harholt J, Qin F, Michel G, Czjzek M, Willats WGT, Herve C. Insoluble (1 → 3), (1 → 4)-β-Dglucan is a component of cell walls in brown algae (Phaeophyceae) and is masked by alginates in tissues. Scientific Reports 2017, 7, 2880.
- Mravec J, Guo X, Hansen AR, Schuckel J, Kracun SK, Mikkelsen MD, Mouille G, Johansen IE, Ulvskov P, Domozych DS, Willats WGT. Pea border cell maturation and release involve complex cell wall structural dynamics. Plant Physiology 2017, 174(2), 1051-1066.
- Andersen MCF, Boos I, Ruprecht C, Willats WGT, Pfrengle F, Clausen MH. Synthesis and Application of Branched Type II Arabinogalactans. Journal of Organic Chemistry 2017, 82(23), 12066-12084.
- Schuckel J, Kracun SK, Willats WGT. High-throughput screening of carbohydrate-degrading enzymes using novel insoluble chromogenic substrate assay kits. Journal of Visualized Experiments 2016, 2016(115), e54286.