Dr Vasilios Andriotis
Lecturer in Metabolic Biochemistry
- Email: email@example.com
- Telephone: +44(0)1912 084510
- Address: Biology - School of Natural and Environmental Sciences
Newcastle-Upon-Tyne, NE1 7RU
- 2017 – Lecturer. Biology - School of Natural and Environmental Sciences, Newcastle University, Newcastle-upon-Tyne, UK
- 2011 – Research Associate. Dept. Metabolic Biology/Biological Chemistry, John Innes Centre, Norwich, UK
- 2008 – Post-doc. CNAP-School of Biology, University of York, York, UK
- 2005 – Post-doc. Dept. Metabolic Biology, John Innes Centre, Norwich, UK
- 2002 – Post-doc.The Sainsbury Laboratory, Norwich, UK
- 2002 – Ph.D. School of Plant Sciences, University of Reading, UK
- 1998 – M.Sc. Crop Physiology, Department of Agricultural Botany, University of Reading, UK
- 1997 – B.Sc. Agriculture and Plant Biology, School of Agriculture, Aristotle University of Thessaloniki, Greece
- Lecturer in Metabolic Biochemistry
- PARTNERS Assessed Summer School - Biological Sciences strand (Co-ordinator)
Plant Physiology, New Phytologist, Biochemical Society Transactions, Molecular Plant Pathology, Planta, Gene Reports
International Association of Sexual Plant Reproduction Research (IASPRR)
Google Scholar page: https://scholar.google.co.uk/citations?user=KLlZ60MAAAAJ
Our expertise is in plant primary metabolism, particularly seed biology and biochemical genetics. We are using molecular and chemical genetics, biochemistry and bioimaging to dissect the link between metabolism and growth in developing and in germinating seeds and seedlings.
We study two fundamental aspects of plant biology:
- how carbohydrate availability coordinates with growth during embryogenesis to regulate seed set, embryo morphogenesis and viability, and
- what post-germination processes in the seedling control root growth and development for successful establishment of the new plant.
We aim to develop an integrated view of seed development and seed germination to inform novel breeding strategies for improved seed quality and yield, essential for food security.
The lab is located at the School of Natural and Environmental Sciences - Devonshire Building. We are part of the Plant and Microbial Sciences Research Group, within the Bioeconomy research focus area of the Biology cluster of the School (http://www.ncl.ac.uk/nes/research/biology/plantandmicrobialsciences/#ourresearch). We are also affiliated with the Newcastle University Centre for Synthetic Biology and the Bioeconomy (http://www.ncl.ac.uk/csbb/).
The lab is always happy to host Stage 3 undergraduate, as well as taught post-graduate students for lab-based projects. We welcome informal enquiries about potential PhD projects related to our research from talented and enthusiastic researchers/students. Please contact Vasilios Andriotis with a CV and research interests to discuss opportunities to join the lab.
- BIO1010 - Biology in Action (Semesters 1 and 2, Stage 1)
- BIO1019 - Introductory Biochemistry for Biologists (Semesters 1 and 2; Stage 1; Module Leader)
- BIO2021 - Employability skills for Biologists (Stage 2)
- BIO3197 - Biological Literature Review (Stage 3)
- BIO3198 - Biological Information Project (Stage 3)
- BIO3199 - Biological Research Project (Stage 3)
- BIO8096 - M.Sc. Industrial and Commercial Biotechnology (Thesis)
March 2018: nominated for NUSU TEA2018 award in the "Outstanding contribution to teaching (SAgE)" category.
- Rugen M, Vernet MJL, Hantouti L, Soenens A, Andriotis VME, Rejzek M, Brett P, van den Berg RJBHN, Aerts JMFG, Overkleeft HS, Field RA. A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals. Scientific Reports 2018, 8, 16421.
- Rugen MD, Andriotis VME, Field RA. Small-Molecule Probes of Plant Glycopolymer Metabolism. In: Reedijk, J, ed. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Elsevier, 2017.
- Andriotis VM, Rejzek M, Barclay E, Rugen MD, Field RA, Smith AM. Cell wall degradation is required for normal starch mobilisation in barley endosperm. Scientific Reports 2016, 6(1), 33215.
- Andriotis VME, Rejzek M, Rugen MD, Svensson B, Smith AM, Field RA. Iminosugar inhibitors of carbohydrate active enzymes that underpin cereal grain germination and endosperm metabolism. Biochemical Society Transactions 2016, 44(1), 159-165.
- Andriotis VM, Saalbach G, Waugh R, Field RA, Smith AM. The Maltase Involved in Starch Metabolism in Barley Endosperm Is Encoded by a Single Gene. PLoS ONE 2016, 11(3), e0151642.
- Andriotis VM, Pike MJ, Schwarz SL, Rawsthorne S, Wang TL, Smith AM. Altered starch turnover in the maternal plant has major effects on Arabidopsis fruit growth and seed composition. Plant Physiology 2012, 160(3), 1175-1186.
- Dave A, Hernández ML, He Z, Andriotis VM, Vaistij FE, Larson TR, Graham IA. 12-oxo-phytodienoic acid accumulation during seed development represses seed germination in Arabidopsis. Plant Cell 2011, 23(2), 583-599.
- Andriotis VME, Kruger NJ, Pike MJ, Smith AM. Plastidial glycolysis in developing Arabidopsis embryos. New Phytologist 2010, 185, 649-662.
- Andriotis VME, Pike MJ, Bunnewell S, Hills MJ, Smith AM. The plastidial glucose 6-phosphate/phosphate antiporter GPT1 is essential for morphogenesis in Arabidopsis embryos. Plant Journal 2010, 64, 128-139.
- Andriotis VME, Pike MJ, Kular B, Rawsthorne S, Smith AM. Starch turnover in developing oilseed embryos. New Phytologist 2010, 187, 791-804.