Staff Profile
Dr Clare Lendrem
Research Associate
- Email: clare.lendrem@ncl.ac.uk
- Telephone: +44 (0) 191 208 3709
- Address: Dr Clare Lendrem CStat
Statistical Methodologist
NIHR Newcastle In Vitro Diagnostics Co-operative
Translational and Clinical Research Institute
Room M2.088
2nd Floor William Leech Building
Newcastle University
Framlington Place
Newcastle upon Tyne
NE2 4HH
Publications
- Price CI, Shaw L, Dixit A, Graziadio S, Lendrem C, Mitra D, Rodgers H, Sutcliffe L, White P. Asymmetrical Bioimpedance in the Anterior Circulation for Urgent Stratification of suspected Stroke (ABACUS Stroke): study protocol for a diagnostic accuracy study. Diagnostic and Prognostic Research 2020, 4, 2.
- Allen AJ, Gonzalez-Ciscar A, Lendrem C, Suklan J, Allen K, Bell A, Baxter F, Crulley S, Fairlie L, Hardy D, Johnston L, McKenna J, Richards N, Shovlin G, Simmister C, Waugh S, Woodsford P, Graziadio S, Power M, Simpson AJ, Kumar P, Eastham K, Brodlie M. Diagnostic and economic evaluation of a point-of-care test for respiratory syncytial virus. ERJ Open Research 2020, 6(3), 00018-2020.
- Hunter E, Price DA, Murphy E, Schim van der Loeff I, Baker KF, Lendrem D, Lendrem C, Schmid ML, Pareja-Cebrian L, Welch A, Payne BAI, Duncan CJA. First experience of COVID-19 screening of health-care workers in England. The Lancet 2020, 395(10234), e77-e78.
- Graziadio S, Winter A, Lendrem BC, Suklan J, Jones WS, Urwin SG, O'Leary RA, Dickinson R, Halstead A, Kurowska K, Green K, Sims A, Simpson AJ, Power HM, Allen AJ. How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development. Micromachines 2020, 11(3), 291.
- McMeekin P, Lendrem DW, Lendrem BC, Pratt AG, Peck R, Isaacs JD, Jones D. Schrödinger's pipeline and the outsourcing of pharmaceutical innovation. Drug Discovery Today 2020, 25(3), 480-484.
- Lendrem BC, Lendrem DW, Pratt AG, Naamane N, McMeekin P, Ng W-F, Allen AJ, Power M, Isaacs JD. Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic. Pharmaceutical Statistics 2019, 18(6), 632-635.
- Tarn JR, Howard-Tripp N, Lendrem DW, Mariette X, Saraux A, Devauchelle-Pensec V, Seror R, Skelton AJ, James K, McMeekin P, Al-Ali S, Hackett KL, Lendrem BC, Hargreaves B, Casement J, Mitchell S, Bowman SJ, Price E, Pease CT, Emery P, Lanyon P, Hunter J, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, Johnsen SJA, Norheim KB, Omdal R, Stocken D, Everett C, Fernandez C, Isaacs JD, Gottenberg J-E, Ng WF, French ASSESS cohort, UK Primary Sjogren's Syndrome Registry. Symptom-based stratification of patients with primary Sjögren’s syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials. Lancet Rheumatology 2019, 1(2), e85-e94.
- Atarod S, Norden J, Bibby LA, Janin A, Ratajczak P, Lendrem C, Pearce KF, Wang XN, O'Reilly S, Van Laar JM, Collin M, Dickinson AM, Crossland RE. Differential MicroRNA Expression Levels in Cutaneous Acute Graft-versus-Host Disease. Frontiers in Immunology 2018, 9, 1485.
- Crossland RE, Norden J, Juric MK, Green K, Pearce KF, Lendrem C, Greinix HT, Dickinson AM. Expression of Serum microRNAs is Altered During Acute Graft-versus-Host Disease. Frontiers in Immunology 2017, 8, 308.
- Boieri M, Ulvmoen A, Sudworth A, Lendrem C, Collin M, Dickinson AM, Kveberg L, Inngjerdingen M. IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo. OncoImmunology 2017, 6(3), e1274478.
- Crossland RE, Norden J, Juric MK, Pearce KF, Lendrem C, Bibby LA, Collin M, Greinix HT, Dickinson AM. Serum and Extracellular Vesicle MicroRNAs miR-423, miR-199, and miR-93* As Biomarkers for Acute Graft-versus-Host Disease. Frontiers in Immunology 2017, 8, 1446.
- Atarod S, Ahmed MA, Lendrem C, Pearce KP, Cope W, Norden J, Wang X, Collin M, Dickinson AM. MiR-146a and miR-155 expression levels in acute graft-versus-host disease incidence. Frontiers in Immunology (Alloimmunity and Transplantation) 2016, 7, 56.
- Lendrem DW, Lendrem BC, Linsley M, Rowland-Jones R, D'Agostino F, Owen MR, Isaacs JD. Teaching Examples for the Design of Experiments: Geographical Sensitivity and the Self-Fulfilling Prophecy. Pharmaceutical Statistics 2016, 15(1), 90-92.
- Atarod S, Pearce K, Norden J, Lendrem C, Crossland R, Wang X, Sviland L, Janin A, Collin M, Dickinson A. Differential microRNA expressions in cutaneous acute graft-versus-host disease. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT). 2015, Istanbul, Turkey.
- Lendrem DW, Lendrem BC, Woods D, Rowland-Jones R, Burke M, Chatfield M, Isaacs JD, Owen MR. Lost in Space: Design of Experiments and Scientific Exploration in a Hogarth Universe. Drug Discovery Today 2015, 20(11), 1365-1371.
- Atarod S, Ahmed M, Lendrem C, Pearce K, Cope W, Norden J, Wang X, Collin M, Dickinson A. MiR-146a and miR-155 expression levels in allogeneic haematopoietic stem cell transplantation patients is predictive of acute graft-versus-host incidence. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Lendrem DW, Lendrem BC, Peck RW, Senn SJ, Day S, Isaacs JD. Progression-seeking bias and rational optimism in research and development. Nature Reviews Drug Discovery 2015, 14, 219-221.
- Peck RW, Lendrem DW, Grant I, Lendrem BC, Isaacs JD. Why is it hard to terminate failing projects in pharmaceutical R&D?. Nature Reviews Drug Discovery 2015, 14, 1-2.
- Lendrem DW, Senn SJ, Lendrem BC, Isaacs JD. R&D Productivity Rides Again?. Pharmaceutical Statistics 2014.
- Lendrem D, Lendrem BC. The Development Speed Paradox: Can increasing development speed reduce R&D productivity?. Drug Discovery Today 2014, 19(3), 209-214.
- Lendrem DW, Lendrem BC. Torching the Haystack: Modelling fast-fail strategies in drug development. Drug Discovery Today 2013, 18(7-8), 331-336.