Staff Profile
Dr Diana Papini
Research Associate
- Email: diana.papini@ncl.ac.uk
- Telephone: 01912085475
- Address: Newcastle University Biosciences Institute (NUBI)
Chromosome biology and the Cell Cycle Team
Jonathan Higgins laboratory
Newcastle University
Medical School
Framlington Place
Newcastle upon Tyne,
NE2 4HH - United Kingdom
RESEARCH INTERESTS:
My research interests are Cell Division, mitosis, chromosome segregation, lagging chromosomes, aneuploidy and chromosome instability (CIN).
SKILLS AND EXPERTISE:
Cell and molecular biology, live and fix high resolution microscopy, super-resolution microscopy (STED and iSIM), and mammalian cell culture including generation of stably expressing fluorescence cell lines.
Protein expression and purification for activity assay (i.e. GEF/kinases proteins) by using Baculovirus system.
TEACHING
During my Postdoctoral I have supervised and mentored several BSc Graduate students, and summer/erasmus students.
At the moment, together with Prof Jon Higgins and Christine Harrison, I am co-supervisor of 3 years Ph.D student funded by The Andrew Walker Cancer Studentship (sponsored by JGW Patterson Foundation).
- Papini D, Fant X, Ogawa H, Desban N, Samejima K, Feizbakhsh O, Askin B, Ly T, Earnshaw WC, Ruchaud S. Cell cycle-independent furrowing triggered by phosphomimetic mutations of the INCENP STD motif requires Plk1. Journal of Cell Science 2019, 132(21), jcs234401.
- Papini D. First Person. Journal of Cell Science 2019, 132(21), jcs240473.
- Papini D, Langemeyer L, Abad MA, Kerr A, Samejima I, Eyers PA, Jeyaprakash AA, Higgins JMG, Barr FA, Earnshaw WC. TD-60 links RalA GTPase function to the CPC in mitosis. Nature Communications 2015, 6, 7678.