Skip to main content

Module

MMB8046 : Drug Delivery and Nanomedicine

  • Offered for Year: 2021/22
  • Module Leader(s): Dr Wing Man Lau
  • Lecturer: Professor Moein Moghimi, Dr Keng Wooi Ng
  • Owning School: FMS Graduate School
  • Teaching Location: Newcastle City Campus
Semesters
Semester 1 Credit Value: 20
ECTS Credits: 10.0

Aims

The module aims to develop the student's knowledge and understanding of the scientific principles of medicine design, development and manufacture. Students will develop the ability to formulate potential novel therapeutic compounds into world-class medicine to address current market needs and propose a sound strategy to do so. It covers the technologies to design, develop and analyse micro and nano-scale materials, systems and devices. Industrial expertise will offer students an insight into pharmaceutical product development.

Outline Of Syllabus

The module covers the following areas, delivered through a series of lectures and interactive face-to-face seminars.

-Biological barriers for drug delivery
-Routes of drug administration
-Drug formulation design and development
-Targeted drug delivery systems and carriers
-Medicines manufacturing and quality control
-Latest advances in drug delivery and targeting
-Personalised medicine
-Pharmaceutical nanotechnology and nanomedicines
-Delivery of biopharmaceuticals

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture101:0010:00Present in person (PIP): Lectures
Guided Independent StudyAssessment preparation and completion175:0075:00Preparation and submission for in-course assessment
Guided Independent StudyDirected research and reading150:0050:00Notes from lectures and reading
Scheduled Learning And Teaching ActivitiesSmall group teaching52:0010:00Present in person (PIP): Tutorials
Scheduled Learning And Teaching ActivitiesSmall group teaching22:004:00Present in person (PIP): Surgery
Scheduled Learning And Teaching ActivitiesSmall group teaching13:003:00Present in person (PIP): Seminars
Scheduled Learning And Teaching ActivitiesSmall group teaching13:003:00Present in person (PIP): Presentation
Guided Independent StudyStudent-led group activity43:0012:00Student-led seminars and meetings
Guided Independent StudyIndependent study133:0033:00Independent study
Total200:00
Teaching Rationale And Relationship

Theoretical content will be provided by lectures and provide a framework on which to construct further guided independent learning. Weekly interactive seminars will involve collaborative problem based activities that will encourage students to apply and build on the previous week’s learning and facilitate deeper learning on current research and development of advanced drug formulation and delivery through social interaction. Tutorial, seminars and student-lead activities also provide an opportunity to develop other skills including interpersonal skill, oral communication, collaboration, critical appraisal and information literacy. Surgery sessions provide extra opportunities for individual learning support that tailor to more specific individual learning needs.

All the teaching sessions are intended to be delivered in-person on campus. However, if the public health situation restricts in-person teaching, these teaching sessions will be delivered remotely.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Other Assessment
Description Semester When Set Percentage Comment
Case study1M65Scientific literature review and prepare a formulation design proposal (max 2500 words)
Report1M35Complete an individual report describing case study formulation design (max 1000 words)
Formative Assessments
Description Semester When Set Comment
Oral Presentation1MPresent in person Oral presentation in small groups (15 minutes)
Assessment Rationale And Relationship

The coursework will allow the students to show that they have fully understood all of the elements required in order to formulate an enhanced drug delivery system. Coursework is preferred as it provides a mechanism for the students to show that they are able to integrate the separate elements together to develop a specific drug formulation design.

Each student will be given a case based on a currently unmet pharmaceutical formulation need. Students will be expected to carry out a literature review to present the current knowledge and, based on that, to derive a proposal to meet the formulation need. Knowledge and skills will also be formatively assessed by small group presentation of a strategy relating to a new formulation development, followed by a question and answer session. This formative assessment will provide an opportunity for further feedback on their formulation design proposal. Each student will then submit a summative written plan to describe their chosen formulation design and how the chosen designed be tested. These tasks have been designed to prepare students for a typical working environment where team work and diplomacy are as important as knowledge.

Should public health circumstances dictate that it is necessary the oral presentation would be moved to an online alternative.

Reading Lists

Timetable