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CME2027 : Process Development Science and Analysis

  • Offered for Year: 2023/24
  • Module Leader(s): Dr Katarina Novakovic
  • Lecturer: Dr Stevin Pramana
  • Owning School: Engineering
  • Teaching Location: Newcastle City Campus
Semester 1 Credit Value: 10
ECTS Credits: 5.0


The aim of the module is to provide overview of the complexity of real chemical systems relevant to successful process development, i.e. conversion of research synthesis into a manufacturing process. The goal is to aid knowledge needed for evaluation of the effect of choices made in developing a synthesis route. Lectures will explain the logic and significance of critical thinking behind multidisciplinary approach required for successful chemical process development by focusing on major points where chemical and process engineering meet. The range of analytical methods and the complexities encountered in measurements and data generation will be shown.

Outline Of Syllabus

Science of process development: Elements required (synthetic organic chemistry, analytical chemistry, physical organic chemistry, chemical engineering, statistical design, physical science, material science, hazard studies); Route selection and measure of process complexity: number of phases, chemical complexity, physical and dynamic complexity; Atom efficiency; Pre-reaction equilibria; Competing reactions and options for influencing selectivity; Multiphase reactions, coupling of chemical and mass transfer rates; Scale up, phase characteristics, chemistry and physical interactions.

Analytical Methods for process/product characterisation: A variety of analytical methods and procedures for the analysis of feedstocks, process and products for selected processes will be discussed. Where appropriate the analysis of side reactions in the processes will be covered. Particularly, spectroscopy (including IR and Raman), separations using chromatography and atomic emission/absorption aspects will be discussed.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion116:0016:00Exam revision
Guided Independent StudyAssessment preparation and completion11:301:30Exam
Scheduled Learning And Teaching ActivitiesLecture231:0023:00Present in person lectures
Guided Independent StudyAssessment preparation and completion11:301:30Formative test
Scheduled Learning And Teaching ActivitiesSmall group teaching101:0010:00Present in person tutorials
Guided Independent StudyIndependent study148:0048:00Review lecture material, tutorials, revisions and extended reading.
Teaching Rationale And Relationship

The predominance of lectures is appropriate for the module. The tutorial sessions provide an opportunity for the
students to practise the numerical methods required for calculations as well as put taught content into a broader
context of a chemical engineering discipline. Throughout the module, students are being prepared for the
assessment and given opportunity to practice each of the elements assessed.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination901A100Timetabled exam in controlled environment
Formative Assessments
Description Semester When Set Comment
Computer assessment1MOnline test to assist learning and preparation for exam - 90 minutes.
Assessment Rationale And Relationship

The final exam tests the knowledge of the students on the concepts taught in the lectures.

Reading Lists