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Module

BMD2017 : Bacterial Cell and Molecular Biology (Inactive)

  • Inactive for Year: 2025/26
  • Module Leader(s): Dr Richard Daniel
  • Co-Module Leader: Dr Ling Juan Wu
  • Lecturer: Dr Katarzyna Mickiewicz, Dr Yulia Yuzenkova, Professor Nicholas Jakubovics, Dr Kevin Whitley, Professor Bert van den Berg, Professor Henrik Strahl von Schulten, Professor Paula Salgado, Dr Alistair Brown, Professor Heath Murray, Dr Charles Winterhalter, Professor Nikolay Zenkin, Dr Sergey Melnikov
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semesters

Your programme is made up of credits, the total differs on programme to programme.

Semester 2 Credit Value: 20
ECTS Credits: 10.0
European Credit Transfer System

Aims

The aim of this module is to provide an overview of the basic biological processes essential for bacterial growth and survival, and how these are exploited by antibiotics including:

Bacterial model system biology



Bacterial development and related gene expression

Molecular targets of antimicrobial agents

Genetic manipulation in bacteria and exploitation of bacterial properties

Outline Of Syllabus

Topics covered by this module include:



1 – Essential Bacterial cell biology, including bacterial cell structure, metabolism, growth requirements, model systems and microbial interactions (e.g. biofilms).

2 – Regulation of bacterial gene expression and its importance in, for example, developmental pathways, cell differentiation (e.g. sporulation), environmental sensing and pathogenicity.

3- Bacterial cell cycle: including growth and division, cell wall synthesis, DNA replication, genome segregation, DNA transfer, recombination and plasmids.

4 - Applications of genetic manipulation in bacteria, such as gene function analysis and metabolic engineering.

5 - Bacteriophage infection, resistance and applications

6 – Cellular processes targeted and exploited by antibiotics

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture201:0020:00Lectures
Scheduled Learning And Teaching ActivitiesSmall group teaching31:003:00Seminars. Preparation for assessments
Scheduled Learning And Teaching ActivitiesWorkshops22:004:00Group workshops - guided discussion
Guided Independent StudyIndependent study1731:00173:00Includes assessment preparation and completion, directed research and reading and student-led group activity
Total200:00
Teaching Rationale And Relationship

Lectures will provide an overview of the subject areas and direct independent study



Seminars / Small group teaching will encourage contextualisation of taught material through discussion. Small group teaching provides support for students in their preparation for the assessment.



Workshops: will provide skills training and assessment guidance, while developing teamwork and communication skills. Workshops will also provide support for students in their preparation for the assessment.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Other Assessment
Description Semester When Set Percentage Comment
Oral Presentation2M40In pairs; 10min presentation
Research proposal2M60Individual; 2000 words max
Formative Assessments

Formative Assessment is an assessment which develops your skills in being assessed, allows for you to receive feedback, and prepares you for being assessed. However, it does not count to your final mark.

Description Semester When Set Comment
Case study2MCase Study Proposal: A group generated brief generic outline with an indication of each area to be focused on as an individual contribution
Assessment Rationale And Relationship

Case Study proposal (formative assessment) – will identify and justify a pathway for study, direct students toward relevant literature and facilitate collaborative interaction and division of work for independent study. Feedback will aid completion of the assessments.



Oral Presentation will assess understanding of the lecture material, ability to apply it to a relevant project, ability to present information orally and ability to work effectively in a small group/pair. Feedback will aid completion of the final assessment assignment.



Research proposal: will assess ability to integrate information and present it effectively in written format

Reading Lists

Timetable