Skip to main content

Module

BMD2018 : Mitochondrial Biology and Function (Inactive)

  • Inactive for Year: 2025/26
  • Module Leader(s): Dr Thomas Nicholls
  • Co-Module Leader: Dr Uwe Richter
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semesters

Your programme is made up of credits, the total differs on programme to programme.

Semester 2 Credit Value: 20
ECTS Credits: 10.0
European Credit Transfer System

Aims

The aim of this module is to:

Introduce the roles of mitochondria in cellular metabolism

Establish a basic understanding of the role of the mitochondrial genome and how it is expressed

Understand the cell biology and dynamics of mitochondria within human cells

Outline Of Syllabus

Topics covered by this module include:



Mitochondrial origins and evolution

Mitochondrial energy metabolism

Mitochondrial gene maintenance and expression

Mitochondrial structure and cell biology

Mitochondria in cell signalling

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture201:0020:00Lectures
Guided Independent StudyAssessment preparation and completion120:0020:00Preparation and writing of data interpretation assessment
Scheduled Learning And Teaching ActivitiesPractical25:0010:00Wet lab using cell lines with mitochondrial dysfunction.
Scheduled Learning And Teaching ActivitiesWorkshops12:002:00Graphical abstract creation guidance session
Guided Independent StudyIndependent study1148:00148:00Writing up lecture notes, reading and revision
Total200:00
Teaching Rationale And Relationship

Lectures introduce the material and provide the bulk of knowledge to allow students to meet the learning outcomes. Lectures will include links for additional material to help guide independent study.

The practical will introduce key research skills and encourage critical interpretation of research data, which will also contribute towards preparation for in-course assessment.

A workshop will provide guidance on critical appraisal of research papers and the creation of graphical abstracts.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Digital Examination1202A60Invigilated Inspera exam. Paper interpretation exercise. Maximum 10 questions
Other Assessment
Description Semester When Set Percentage Comment
Report2M40Data interpretation report - Students interpret data from practical, as well as complementary provided data, on cell lines with different mitochondrial defects, and write a report on the likely genetic causes (maximum 1500 words).
Formative Assessments

Formative Assessment is an assessment which develops your skills in being assessed, allows for you to receive feedback, and prepares you for being assessed. However, it does not count to your final mark.

Description Semester When Set Comment
Prob solv exercises2MOnline Quizzes: Series of online Canvas quizzes to be used to consolidate knowledge from the taught material
Assessment Rationale And Relationship

The data interpretation assesses students’ ability to interpret scientific results and incorporate aspects of learning from the taught material and from independent study.

A formal exam will assess the students’ overall understanding of the content of the taught material as well as their ability to apply knowledge to a research paper on a topic relevant to the material.

Formative online quizzes will help support student’s understanding of key details relating to mitochondria.

Reading Lists

Timetable