Skip to main content

Module

BMD3016 : Microbiota and Pathogens in Fundamental Research and the Clinic (Inactive)

  • Inactive for Year: 2025/26
  • Module Leader(s): Professor Robert Hirt
  • Co-Module Leader: Dr David Bolam
  • Lecturer: Professor Christopher Stewart, Professor Janet Quinn, Dr Anjam Khan, Dr Carys Watts, Dr Kate Beckham, Professor Jeffrey Pearson
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semesters

Your programme is made up of credits, the total differs on programme to programme.

Semester 1 Credit Value: 20
ECTS Credits: 10.0
European Credit Transfer System

Aims

The module aims to develop knowledge and understanding of the fundamental importance in human health and disease of host-microbe interactions at mucosal surfaces with a focus the following four key points:

Fundamentals of mucosal immunology of the digestive, urogenital and the respiratory tracts

The role of the gut microbiota in both health and disease, including selected common chronic diseases

A selection of common bacterial, microbial eukaryotic and viral pathogens and how they interact with the human microbiota and immune system

A selection of prophylactic and therapeutic approaches to combat microbial pathogens

Outline Of Syllabus

The module will cover the following topics:

The multifaceted and ubiquitous importance of the gut microbiota in human heath

Fundamentals of microbiota-mucosal immune system interactions and their importance in resistance to pathogens

The use of comparative genomics and related omics in fundamental and clinical research to study the causal links between the microbiota and pathogens with selected acute and chronic diseases

Contrast the biology of selected extracellular and intracellular pathogens and the corresponding mucosal immunological responses to these pathogens

Selected pathogenic bacteria, fungi, parasitic protozoa and viruses infecting the digestive, urogenital or respiratory tracts

Vaccination strategies and drug treatment options and the challenges of drug resistance and development for selected common pathogens

The use of AI in research, with a focus on literature search and interpretation of complex data

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture201:0020:00Lectures
Scheduled Learning And Teaching ActivitiesSmall group teaching12:002:00Seminar 2. Feedback on coursework and general Q&A session.
Scheduled Learning And Teaching ActivitiesSmall group teaching11:001:00Seminar 1: Module overview
Scheduled Learning And Teaching ActivitiesWorkshops23:006:00Workshop (computer lab). AI and literature search workshops on selected topics relating to microbiota and pathogens and data analysis
Guided Independent StudyIndependent study1171:00171:00Includes: Assessment preparation and completion, directed research and reading
Total200:00
Teaching Rationale And Relationship

Lectures will provide students with key information (K1-3).

Workshops will develop students’ skills in literature search, critically interpret the research literature and contribute to increased understanding of the material through discussion of journal articles (S1-2). Workshops will also include Q&A sessions, and will help the student in preparing for coursework and formal examination (S3).

Seminars will provide module overview, coursework feedback and further opportunity for Q&As

Guided Independent study will allow students to extend their knowledge through reading of journal articles and other recommended references required for the writing of the short essay and figure/table generation (S2, S3).

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Written Examination1202A60closed-book 2 essays questions from a choice of 4, 60 mins per question
Other Assessment
Description Semester When Set Percentage Comment
Written exercise1M40Short essay/report: Open book essay (2000 words) based on whole group activity that aims to test and develop critical thinking and analytical skills, as well as knowledge and understanding of what has been taught and practiced during the workshops
Assessment Rationale And Relationship

Essay (exam and course-work) : The essay writing, including compulsory generation of 2 illustrations and use of 1 table to synthetize data and complex concepts will test students' knowledge, understanding, written communication and illustration generation skills.

Reading Lists

Timetable