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NES8802 : Drug Metabolism and Toxicology

  • Offered for Year: 2024/25
  • Module Leader(s): Professor Mike Waring
  • Lecturer: Dr Kate Harris
  • Owning School: Natural and Environmental Sciences
  • Teaching Location: Newcastle City Campus

Your programme is made up of credits, the total differs on programme to programme.

Semester 1 Credit Value: 10
ECTS Credits: 5.0
European Credit Transfer System


To introduce the principles of pharmacokinetics, drug metabolism and toxicology; to understand the importance of optimising these parameters in drug discovery; to understand the chemical basis of drug metabolism and its importance in drug discovery; to equip students with a knowledge and understanding of the mechanism of toxicity of drug molecules and other the environmental toxins

Outline Of Syllabus

Pharmacokinetics and drug metabolism (Professor M Waring)
Principles of pharmacokinetics
Processes and mechanisms of drug metabolism
Selected case studies in drug metabolism

Toxicology (Dr Kate Madden)
Principles of Toxicology and toxicokinetics
Critical toxicological issues for drug discovery
Allergens and reactive metabolites
Ion channels – hERG and acetyl choline signalling

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion120:0020:00Revision for end of Semester 1 examination
Guided Independent StudyAssessment preparation and completion210:0020:00Online assessments - Structured literature exercise: case study and literature reading
Guided Independent StudyAssessment preparation and completion121:0012:00Online materials via Canvas
Scheduled Learning And Teaching ActivitiesLecture121:0012:00PiP lectures
Guided Independent StudyAssessment preparation and completion12:002:00End of Semester examination
Guided Independent StudyIndependent study134:0034:00Independent study
Teaching Rationale And Relationship

Students acquire knowledge and understanding through online lecture content and live module talks. Problem-solving skills are practiced in module talks and in private study.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination1201A50PiP exam
Other Assessment
Description Semester When Set Percentage Comment
Computer assessment1M50Online assessment
Formative Assessments

Formative Assessment is an assessment which develops your skills in being assessed, allows for you to receive feedback, and prepares you for being assessed. However, it does not count to your final mark.

Description Semester When Set Comment
Prob solv exercises1MOnline canvas quiz
Assessment Rationale And Relationship

The exam will test the student’s knowledge and understanding of the coursework as well as information literacy and presentation skills.

Formative assessment to allow student to test their understanding of module so far.

Study Abroad students may request to take their exam before the semester 1 exam period, in which case the format of the paper may differ from that shown in the MOF. Study Abroad students should contact the school to discuss this.

Reading Lists