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Module

BGM2056 : DNA Replication, recombination and Repair

  • Offered for Year: 2020/21
  • Module Leader(s): Dr Simon Whitehall
  • Lecturer: Professor Heath Murray
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semesters
Semester 2 Credit Value: 10
ECTS Credits: 5.0

Aims

1. To provide a sound understanding of the molecular mechanisms underlying the replication, repair and recombination of DNA and to demonstrate the unique importance of the accuracy of these processes.

2. To provide a framework for understanding the different types of DNA damage, the mechanisms by which they are repaired and the diseases that result from defects in these repair processes.

Outline Of Syllabus

This module provides an understanding of the following key DNA-dependent processes:

accurate replication of the genome and recombination;
mechanisms of genetic variation;
repair of DNA damage;
results of failure to correct DNA damage (e.g. mutation, genetic instability, cancer).
development of genetics diseases (e.g. developmental disorders, cancer predisposition and premature ageing)

Teaching Methods

Module leaders are revising this content in light of the Covid 19 restrictions.
Revised and approved detail information will be available by 17 August.

Assessment Methods

Module leaders are revising this content in light of the Covid 19 restrictions.
Revised and approved detail information will be available by 17 August.

Reading Lists

Timetable