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Module

PED3005 : Advanced Pharmacogenetics

  • Offered for Year: 2021/22
  • Module Leader(s): Professor Ann Daly
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semesters
Semester 1 Credit Value: 10
ECTS Credits: 5.0

Aims

To provide information on how genetic factors affect the metabolism of foreign compounds and drug receptor
interactions.

To develop knowledge on the importance of inter-individual variability in drug metabolism in the drug
development process and in therapeutics.

To discuss current views on the relationship between pharmacogenetic polymorphisms and disease
susceptibility and potential approaches to drug design using pharmacogenomics.
To provide an introduction to molecular epidemiology.

To develop knowledge of the molecular basis of polymorphisms in drug metabolizing enzymes,
including the cytochromes P450, the glutathione S-transferases and N-acetyltransferases as well as
polymorphisms in drug receptors and other drug targets.

Outline Of Syllabus

See above.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture141:0014:00PIP
Guided Independent StudyAssessment preparation and completion11:001:00PIP - EMI assessment
Guided Independent StudyIndependent study185:0085:00Writing up lecture notes, revision and general reading.
Total100:00
Teaching Rationale And Relationship

Lectures will define the scope of the course and communicate knowledge as a basis for further study. This is an advanced course involving reading of research as well as advanced textbooks.



Public Health Contingency:
All lectures and assessments can/will move online either as synchronous online delivery.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Written Examination902A80Invigilated exam. Answer 2 from 4 questions.
Other Assessment
Description Semester When Set Percentage Comment
Prob solv exercises1M20Invigilated EMI (1 hour duration)
Assessment Rationale And Relationship

The EMI assesses student knowledge and understanding of course material.

FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.



Public health contingency:
Examination will move to (online) – Open Book Essay (1 essay from a choice of 2) 5-7 day completion period.
Invigilated EMI will move to (online) – timed Canvas EMI (60 mins)

Reading Lists

Timetable