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Module

MMB8015 : Applied Immunobiology of Human Disease

  • Offered for Year: 2020/21
  • Module Leader(s): Dr Catharien Hilkens
  • Lecturer: Dr Amy Anderson, Professor Andrew Gennery, Professor Sophie Hambleton, Professor John Isaacs, Professor Kevin Marchbank, Professor John Kirby, Professor Simi Ali, Dr Andrew Filby, Professor David Jones, Dr Lei Huang
  • Owning School: FMS Graduate School
  • Teaching Location: Newcastle City Campus
Semesters
Semester 1 Credit Value: 20
ECTS Credits: 10.0

Aims

The purpose of this module is to provide an up-to-date overview and introduction to selected aspects of Immunobiology. The module will comprise a series of lectures on recent developments, with an emphasis on understanding the supportive biological concepts. This module aims to address a major area of current medical research and to provide students with an understanding of the strengths and weakness of both the current subject knowledge in this area and the practical approaches to it. This module is designed to be multi-disciplinary, drawing upon the specialized expertise and research strengths of academic staff drawn from the Faculty of Medical Sciences. It will provide a strong platform for those students aiming to pursue research projects in cellular or molecular immunology.

Outline Of Syllabus

The syllabus contains the following topics:

• Basic concepts in immunology
• T cell responses in health and disease
• Generation of B cell immunity
• General features and mechanisms of immunologic tolerance
• Regulation of immunity and tolerance by dendritic cells
• Cell migration in the immune system
• Transplantation and graft rejection
• Immunodeficiency disorders
• Autoimmunity: mechanisms and treatment
• Tumour Immunobiology
• Manipulation of innate immunity for immunotherapy
• Immunological defence mechanisms in infection
• New developments in cytometry-based technologies – applications in immunology
• Immunological Biomarkers: role in diagnostics, prognostics and theragnostics

Teaching Methods

Please note that module leaders are reviewing the module teaching and assessment methods for Semester 2 modules, in light of the Covid-19 restrictions. There may also be a few further changes to Semester 1 modules. Final information will be available by the end of August 2020 in for Semester 1 modules and the end of October 2020 for Semester 2 modules.

Teaching Activities
Category Activity Number Length Student Hours Comment
Structured Guided LearningLecture materials141:0014:00Non-synchronous online
Guided Independent StudyAssessment preparation and completion146:0046:00Preparation for and completion of a graphical presentation
Guided Independent StudyAssessment preparation and completion170:0070:00Preparation of 2000 word Essay
Scheduled Learning And Teaching ActivitiesSmall group teaching91:009:00Present in person: Seminars on a variety of topics to complement the lecture materials
Guided Independent StudyReflective learning activity160:0060:00Reading and updating on subject using references from lecture materials, RECAP and other sources
Scheduled Learning And Teaching ActivitiesDrop-in/surgery11:001:00Present in person: questions in relation to the assessments
Total200:00
Teaching Rationale And Relationship

Lecture materials delivered online will provide the students with a specific knowledge as a platform for private study. These lecture materials and small group teaching will encourage the students to reflect both individually and in small groups on the state of knowledge in research in applied immunobiology. All of these activities relate directly to the learning outcomes above.

Assessment Methods

Please note that module leaders are reviewing the module teaching and assessment methods for Semester 2 modules, in light of the Covid-19 restrictions. There may also be a few further changes to Semester 1 modules. Final information will be available by the end of August 2020 in for Semester 1 modules and the end of October 2020 for Semester 2 modules.

The format of resits will be determined by the Board of Examiners

Other Assessment
Description Semester When Set Percentage Comment
Essay1M602000 words
Written exercise1M40Generation of 1 powerpoint slide plus notes
Assessment Rationale And Relationship

The essay will test students' detailed knowledge and critical understanding of a selected area of applied immunology. The ‘single slide summary’ assessment will test the students’ ability to succinctly and clearly summarise a selected aspect of the immune response within a single PowerPoint slide, making use of graphics and text boxes

Reading Lists

Timetable