Skip to main content


MMB8035 : Diabetes

  • Offered for Year: 2022/23
  • Module Leader(s): Dr Catherine Arden
  • Lecturer: Dr Jolanta Weaver, Miss Alison Barnes, Prof. Mark Walker, Prof. Philip Home, Dr Carl Hulston, Professor James Shaw, Professor Quentin Anstee, Dr Nicola Leech, Dr Daniel West
  • Owning School: FMS Graduate School
  • Teaching Location: Newcastle City Campus
Semester 1 Credit Value: 20
ECTS Credits: 10.0


The module aims to provide an introduction to clinical aspects of diabetes mellitus and its complications, based on an understanding of the underlying basic metabolic control processes, and to build knowledge and understanding of diabetes care and research, including an increased awareness of the clinical research tools available for the study of the disease and its complications.

Outline Of Syllabus

The taught component of the module is delivered through lectures, seminars and practical sessions. The topics covered include: the genetics of diabetes; genetic epidemiology, bioinformatics and epigenetics; glucose and lipid metabolism in the fed an fasted state and their perturbation in diabetes; biochemical mechanisms of insulin secretion; insulin resistance; assessment of beta cell function; exercise in diabetes; prevention of type 2 diabetes at the population and individual level; prediction of type 1 diabetes and treatment by immunotherapeutic intervention; transplantation and regenerative medicine approaches for diabetes; factors contributing to the development of complications in diabetes; vascular studies in diabetes; liver disease in diabetes; designing, monitoring and conducting clinical trials; the use of technology in diabetes care.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture21:002:00Synchronous online lectures
Guided Independent StudyAssessment preparation and completion155:0055:00Preparing for presentation and examination
Scheduled Learning And Teaching ActivitiesLecture171:0017:00Present in person (PIP): Lectures
Scheduled Learning And Teaching ActivitiesPractical11:001:00Present in person (PIP): Practical Sessions on insulin resistance measurements
Scheduled Learning And Teaching ActivitiesSmall group teaching31:003:00Present in person (PIP): Seminars in small groups
Scheduled Learning And Teaching ActivitiesSmall group teaching14:004:00Present in person: Oral assessment
Scheduled Learning And Teaching ActivitiesSmall group teaching11:001:00Present in person (PIP): Group oral presentations on clinical trial design
Guided Independent StudyReflective learning activity132:0032:00Additional reading and reflective learning
Guided Independent StudyIndependent study185:0085:00Preparing notes from lectures and additional reading
Teaching Rationale And Relationship

The interactive small group teaching and lectures will provide the students with current specialist knowledge on which to build in independent learning. The seminars will encourage students to reflect and question individually and in groups providing a basis for critical appraisal, innovative thinking about diabetes and study design. The practical sessions will provide opportunity to observe and discuss specific clinical research methodologies and to interpret data. All of these activities relate directly to the learning outcomes above.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination601A60Present in person Examination: One hour paper with a choice of 3 essay questions. Students will answer one questions only
Other Assessment
Description Semester When Set Percentage Comment
Prof skill assessmnt1M40Present in person Individual Presentation: 10 minutes & 5 for questions on a current paper in diabetes research
Formative Assessments
Description Semester When Set Comment
Oral Presentation1MPresent in person Group Presentation 10 mins plus 5 mins Q & A
Assessment Rationale And Relationship

The exam will test the student’s knowledge base, comprehension and ability to discuss the subject critically.

The oral presentation based on appraisal of scientific literature tests application of knowledge, understanding and ability to critically assess and interpret scientific work. These activities will also assess generic skills of written and oral communication and presentation.

The formative group presentation is run to help students understand how to design a clinical trial.

Reading Lists