Skip to main content

Module

BGM1004 : Genetics

  • Offered for Year: 2020/21
  • Module Leader(s): Dr Jeremy Brown
  • Lecturer: Mr Gareth Breese, Professor Brian Morgan, Professor Deborah Henderson, Prof. Sir John Burn, Dr Simon Whitehall, Professor T. Martin Embley, Dr Damian Parry, Professor Colin Harwood
  • Other Staff: Dr Simon Bamforth, Dr Michael Jackson, Dr Catherine Meplan, Dr Alison Day, Dr Helen Phillips, Dr Gavin Hudson, Professor David Lydall, Dr Laura Maringele
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semesters
Semester 1 Credit Value: 15
ECTS Credits: 8.0

Aims

The aims of this module are to;
• introduce the fundamental principles of Mendelian genetics, population genetics and current concepts of molecular genetics applied to bacteria and eukaryotes required by all bioscience students;
• provide an opportunity for students to interpret genetic information and work through problems in seminars, and relate their knowledge of genetics to laboratory classes in associated modules;
• increase awareness of human genetic diseases and the application of analytical techniques to their diagnosis and potential treatment.
• introduce some of the molecular and genetic techniques being used in the postgenomic
era of genetics as well as recent advances in genetic analysis including the use of model organisms
• provide sufficient knowledge and understanding of the subject to inform student choice to study genetics in phase 2 of the degree.

Outline Of Syllabus

Lectures and seminars will cover the following topics:
• Evolutionary genetics: prebiotic chemistry; ribozymes as molecular fossils; molecular phylogenetics and population genetics.
• Molecular genetics: introduction to bacterial genetics; structure of the bacterial chromosome; comparative genomics; DNA replication and fidelity.
• Eukaryote and Human Genetics: model eukaryotic organisms for genetic analysis; organization of eukaryotic genomes; mitosis and meiosis; sex determination, eukaryotic genes and transcripts; inheritance; recombination & genetic diversity; genome evolution & multigene families.
• Developmental and Medical Genetics: genetic analysis of human disease; modern methods of mapping susceptibility alleles; yeast as a human disease model; clinical genetics of complex diseases; ethics in Genetics

Teaching Methods

Please note that module leaders are reviewing the module teaching and assessment methods for Semester 2 modules, in light of the Covid-19 restrictions. There may also be a few further changes to Semester 1 modules. Final information will be available by the end of August 2020 in for Semester 1 modules and the end of October 2020 for Semester 2 modules.

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion11:001:00Formative class tests
Structured Guided LearningLecture materials201:0020:00Remaining lectures. Non-synchronous online
Scheduled Learning And Teaching ActivitiesSmall group teaching31:003:00Seminars offered as PIP to 1/3 of the cohort for each seminar. Remainder as synchronous online
Scheduled Learning And Teaching ActivitiesDrop-in/surgery30:301:30Synchronous Q&A sessions, cohort split into 3 with each group having 30,minutes
Guided Independent StudyIndependent study1118:30118:30Writing up lecture notes, revision and general reading.
Scheduled Learning And Teaching ActivitiesModule talk61:006:00Lectures 1-3 and 24-26. Synchronous online
Total150:00
Teaching Rationale And Relationship

1. Module talks and lecture materials will define the scope of the course and communicate basic knowledge as a basis for further study.

2. Seminars will encourage students to develop their understanding of the subject and interpersonal communication skills. They provide an opportunity for students to ask questions and exchange ideas in a small group setting. Skills practiced include critical thinking, numeracy, communication & team working.

3. Private study is used for self-directed learning and includes: reading lecture notes and texts; preparation for seminars; using learning resources on the Web. Skills practiced include critical thinking, active learning, numeracy, planning and organisation and independence.

Assessment Methods

Please note that module leaders are reviewing the module teaching and assessment methods for Semester 2 modules, in light of the Covid-19 restrictions. There may also be a few further changes to Semester 1 modules. Final information will be available by the end of August 2020 in for Semester 1 modules and the end of October 2020 for Semester 2 modules.

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
PC Examination901A100Online timed computer based exam (remote) MCQ/Quiz format (expected completion time 90 minutes).
Formative Assessments
Description Semester When Set Comment
Computer assessment1MOnline timed computer based exam (remote) timed MCQ exam (formative)
Assessment Rationale And Relationship

The end of semester MCQ assesses knowledge and understanding of the course material. The formative MCQ questions will help students assess their knowledge and understanding of course material as well as familiarise students with the format of an MCQ exam.

FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submission dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.

Reading Lists

Timetable