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BGM2062 : Advanced Protein Analysis

  • Offered for Year: 2019/20
  • Module Leader(s): Dr Joseph Gray
  • Lecturer: Dr Simon Cockell, Dr Jeremy Brown, Dr Paula Salgado, Professor Jeremy Lakey
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Newcastle City Campus
Semester 2 Credit Value: 10
ECTS Credits: 5.0


This module is designed to equip students with an understanding of modern laboratory-based protein analysis techniques, training in the use of protein data analysis programs, experience in producing and delivering a scientific presentation and writing an extended scientific essay.

Outline Of Syllabus

•       Mass spectrometry and proteomics
•       Bioinformatics
•       Measurement of protein-protein interactions and protein stability
•       Low and high resolution structural biology

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion13:003:00Oral Presentation
Scheduled Learning And Teaching ActivitiesLecture131:0013:00Lectures
Scheduled Learning And Teaching ActivitiesPractical24:008:00IT Practical
Scheduled Learning And Teaching ActivitiesSmall group teaching11:001:00Seminar
Guided Independent StudyIndependent study175:0075:00N/A
Teaching Rationale And Relationship

Lectures are used to introduce a number of key protein ‘handling’ methodologies and principles and practicalities of advanced data analysis.
The seminar will be used to provide feedback on student performance in assessment.
The practical sessions in the IT cluster will give students an opportunity to generate data from the analysis of proteins and use dedicated protein analysis software. These data will then be written up and analysed in conjunction with additional provided data which can be incorporated and presented in the various assessments. The practical session is important to demonstrate the lab/computer interface and develop student’s skills in producing, finding, collating and assimilating scientific data.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Other Assessment
Description Semester When Set Percentage Comment
Computer assessment2M35Computer-based practical report and data analysis (1,500-2,000 words)
Case study2M25Oral presentation (5 mins + 5 mins questions)
Essay2M40Extended essay (2,000 words)
Assessment Rationale And Relationship

The oral presentation will require each student to present a 5 minute presentation to their peers and answer questions from the audience. Each student will be given a different biochemical topic randomly allocated.
The practical report provides the students with an opportunity to write a formal lab report and will incorporate data and results from specialist software programs.
The extended essay will provide students with the opportunity to explore a particular topic covered in the module in greater depth and stimulates wider reading.

Reading Lists