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CME8127 : Bioprocess Engineering

  • Offered for Year: 2022/23
  • Module Leader(s): Professor Jarka Glassey
  • Lecturer: Dr Marloes Peeters
  • Owning School: Engineering
  • Teaching Location: Newcastle City Campus
Semester 1 Credit Value: 10
ECTS Credits: 5.0


This module extends the biochemical engineering knowledge of students by providing basic understanding of the latest developments in bioprocess development, modelling, monitoring and control. To provide chemical engineers with a background knowledge in the area of bioprocess development with emphasis on biopharma , latest research developments in bioprocess modelling and control. These areas are exceedingly sought after by the (bio)pharmaceutical industries.

Outline Of Syllabus

Quality by Design and Process Analytical Technologies as a demonstration of structured approach to bioprocess development, aseptic sampling, latest measurement devices for biomass concentration analyses, data-based modelling techniques in bioprocess modelling, process development, supervision and control.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture151:0015:00N/A
Guided Independent StudyAssessment preparation and completion251:0025:00Preparation and completion of report
Guided Independent StudyAssessment preparation and completion131:0031:00Preparation and delivery of group presentations
Scheduled Learning And Teaching ActivitiesSmall group teaching22:004:00Computer practice
Guided Independent StudyIndependent study125:0025:00Review lecture material, prepare for small group teaching
Teaching Rationale And Relationship

The lectures will introduce concepts of aseptic sampling, measurement methods, data treatment, modelling and application of models in bioprocess development, optimisation, monitoring and control.
Research on the report topic will provide experience of advanced process development and report preparation Alternatives will be offered to students unable to be present-in-person due to the prevailing C-19 circumstances. Students should consult their individual timetable for up-to-date delivery information.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Oral Presentation151M40Group presentation on advanced monitoring and development of bioprocesses,15mins. Question posing/handling included in the mark.
Other Assessment
Description Semester When Set Percentage Comment
Report1M60Group Bioprocess development assignment, maximum 3000 words plus graphs.
Assessment Rationale And Relationship

The oral presentation will test the students’ knowledge and understanding of the module, their ability to critically review a range of literature sources and explain specific concepts of advanced monitoring and development techniques to wider audience. Critical review of literature is an important skills in preparation for Research project (positively commented on by External Examiner and discussed with UG Dean). Given the effort required, this needs to be summative.
Assignment report will assess the remaining skills outcomes. No adjustment required for Covid-19 (in-course assessed).

Reading Lists